8AQF
 
 | | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | | 分子名称: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | | 著者 | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | | 登録日 | 2022-08-12 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy
To Be Published
|
|
7N95
 | | state 1 of TcdB and FZD2 at pH5 | | 分子名称: | Frizzled-2, Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-16 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N9Q
 | | State 3 of TcdB and FZD2 at pH5 | | 分子名称: | Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-18 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N97
 | | State 2 of TcdB and FZD2 at pH5 | | 分子名称: | Frizzled-2, Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-17 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of the Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N9R
 | | state 4 of TcdB and FZD2 at pH5 | | 分子名称: | Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-18 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N9S
 | | TcdB and frizzled-2 CRD complex | | 分子名称: | Frizzled-2, Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-18 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N9Y
 | | Full-length TcdB and CSPG4 (401-560) complex | | 分子名称: | Chondroitin sulfate proteoglycan 4, Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-18 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
7N8X
 | | Partial C. difficile TcdB and CSPG4 fragment | | 分子名称: | Chondroitin sulfate proteoglycan 4, Toxin B | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2021-06-16 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification
To Be Published
|
|
1EHC
 | | STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY | | 分子名称: | CHEY, SULFATE ION | | 著者 | Jiang, M, Bourret, R, Simon, M, Volz, K. | | 登録日 | 1996-03-05 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.3 A structure of an aspartate to lysine mutant at position 13 of CheY.
J.Biol.Chem., 272, 1997
|
|
8FH3
 | | Human IFT-A complex structures provide molecular insights into ciliary transport | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Tubby-related protein 3, ... | | 著者 | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | | 登録日 | 2022-12-13 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Human IFT-A complex structures provide molecular insights into ciliary transport.
Cell Res., 33, 2023
|
|
8FGW
 | | Human IFT-A complex structures provide molecular insights into ciliary transport | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | | 著者 | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | | 登録日 | 2022-12-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Human IFT-A complex structures provide molecular insights into ciliary transport.
Cell Res., 33, 2023
|
|
7UJJ
 | | Stx2a and DARPin complex | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2022-03-30 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits.
Bioengineering (Basel), 9, 2022
|
|
8U7Y
 | |
8CB2
 | |
8DOL
 | | Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ | | 分子名称: | Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION | | 著者 | Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y. | | 登録日 | 2022-07-13 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ.
Nat Commun, 14, 2023
|
|
1M5Z
 | | The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area | | 分子名称: | AMPA receptor interacting protein | | 著者 | Feng, W, Fan, J, Jiang, M, Shi, Y, Zhang, M. | | 登録日 | 2002-07-11 | | 公開日 | 2002-11-06 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
J.Biol.Chem., 277, 2002
|
|
3FIF
 | | Crystal structure of the ygdR protein from E.coli. Northeast Structural Genomics target ER382A. | | 分子名称: | Uncharacterized ligand, Uncharacterized lipoprotein ygdR | | 著者 | Kuzin, A.P, Su, M, Seetharaman, J, Rossi, P, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J.C, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-12-11 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the ygdR protein from E.coli. Northeast Structural Genomics target ER382A.
To be Published
|
|
8H3T
 | | The crystal structure of AlpH | | 分子名称: | AlpH, GLYCEROL | | 著者 | Zhao, Y, Li, M, Jiang, M, Pan, L.F. | | 登録日 | 2022-10-09 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.866 Å) | | 主引用文献 | O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis.
Nat Commun, 14, 2023
|
|
2NWT
 | | NMR Structure of Protein UPF0165 protein AF_2212 from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83 | | 分子名称: | UPF0165 protein AF_2212 | | 著者 | Singarapu, K.K, Sukumaran, D.K, Parish, D, Atreya, H.S, Liu, G, Eletsky, A, Chen, C.X, Jiang, M, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-11-16 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of Protein Y2212_ARCFU from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83
To be Published
|
|
3NNQ
 | | Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | | 分子名称: | ACETATE ION, N-terminal domain of Moloney murine leukemia virus integrase, ZINC ION | | 著者 | Guan, R, Xiao, R, Acton, T, Jiang, M, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-06-24 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | | 主引用文献 | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.
Proteins, 85, 2017
|
|
4NZG
 | | Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Integrase p46, ... | | 著者 | Guan, R, Jiang, M, Janjua, H, Maglaqui, M, Zhao, L, Xiao, R, Acton, T.B, Everett, J.K, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2013-12-12 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | | 主引用文献 | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.
Proteins, 85, 2017
|
|
2LEK
 | | Solution NMR structure of a Thiamine Biosynthesis (ThiS) Protein RPA3574 from Rhodopseudomonas palustris refined with NH RDCs. Northeast Structural Genomics Consortium target RpR325 | | 分子名称: | Putative thiamin biosynthesis ThiS | | 著者 | Ramelot, T.A, Cort, J.R, Lee, H, Wang, H, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Acton, T.B, Xiao, R, Swapna, G, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-06-16 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of a Thiamine Biosynthesis (ThiS) Protein RPA3574 from Rhodopseudomonas palustris. Northeast Structural Genomics Consortium target RpR325
To be Published
|
|
2JPU
 | | solution structure of NESG target SsR10, Orf c02003 protein | | 分子名称: | Orf c02003 protein | | 著者 | Wu, Y, Singarapu, K.K, Zhang, Q, Eletski, A, Xu, D, Sukumaran, D, Parish, D, Wang, D, Jiang, M, Cunningham, K, Maglaqui, M, Owens, L, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-05-23 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of NESG target SsR10, Orf c02003 protein
To be Published
|
|
2K1G
 | | Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162 | | 分子名称: | Lipoprotein spr | | 著者 | Aramini, J.M, Rossi, P, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-03-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.
Biochemistry, 47, 2008
|
|
2DO8
 | | Solution Structure of UPF0301 protein HD_1794 | | 分子名称: | UPF0301 protein HD_1794 | | 著者 | Zhang, Q, Liu, G, Shastry, R, Jiang, M, Cunningham, K, Ma, L.C, Xiao, R, Acton, T.R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-04-27 | | 公開日 | 2006-05-25 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of UPF0301 protein HD_1794
To be published
|
|
