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5SYT
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BU of 5syt by Molmil
Crystal Structure of ZMPSTE24
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CAAX prenyl protease 1 homolog, ...
著者Clark, K, Jenkins, J.L, Fedoriw, N, Dumont, M.E, Membrane Protein Structural Biology Consortium (MPSBC)
登録日2016-08-11
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors.
Protein Sci., 26, 2017
5W0H
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BU of 5w0h by Molmil
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
分子名称: Splicing factor U2AF 65 kDa subunit
著者Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
登録日2017-05-30
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5W0G
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BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
著者Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
登録日2017-05-30
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
2RBF
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BU of 2rbf by Molmil
Structure of the ribbon-helix-helix domain of Escherichia coli PutA (PutA52) complexed with operator DNA (O2)
分子名称: Bifunctional protein putA, DNA (5'-D(*DTP*DT*DTP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DCP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DGP*DAP*DAP*DAP*DGP*DGP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DAP*DAP*DA)-3')
著者Tanner, J.J.
登録日2007-09-18
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.
J.Mol.Biol., 381, 2008
6PJV
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BU of 6pjv by Molmil
Structure of Human Sonic Hedgehog in complex with Zinc and Magnesium
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Bonn-Breach, R.B, Jenkins, J.L, Wedekind, J.E.
登録日2019-06-28
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design.
Acta Crystallogr D Struct Biol, 75, 2019
4CI1
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BU of 4ci1 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
4CI2
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BU of 4ci2 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to lenalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Lenalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
4CI3
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BU of 4ci3 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Pomalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
8FLK
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BU of 8flk by Molmil
Cryo-EM structure of STING oligomer bound to cGAMP and NVS-STG2
分子名称: 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, cGAMP
著者Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y.
登録日2022-12-21
公開日2023-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Activation of human STING by a molecular glue-like compound.
Nat.Chem.Biol., 20, 2024
8FLM
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BU of 8flm by Molmil
Cryo-EM structure of STING oligomer bound to cGAMP, NVS-STG2 and C53
分子名称: 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, ...
著者Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y.
登録日2022-12-21
公開日2023-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Activation of human STING by a molecular glue-like compound.
Nat.Chem.Biol., 20, 2024
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