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Structure of the A138T promiscuous mutant of the EcoRI restriction endonuclease bound to its cognate recognition site.
Descriptor:	DNA (5'-D(TPCPGPCPGPAPAPTPTPCPGPCP*G)-3'), Type II restriction enzyme EcoRI
Authors:	Sapienza, P.J, Rosenberg, J.M, Jen-Jacobson, L.
Deposit date:	2007-02-21
Release date:	2007-10-23
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Structural and thermodynamic basis for enhanced DNA binding by a promiscuous mutant EcoRI endonuclease. Structure, 15, 2007

Crystal structure of the ternary EcoRV-DNA-Lu complex with cleaved DNA substrate.
Descriptor:	1,2-ETHANEDIOL, DNA (5'-D(APAPAPGPAPTP)-3'), DNA (5'-D(APTPCPTPTPTP)-3'), ...
Authors:	Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L.
Deposit date:	2016-01-15
Release date:	2016-11-09
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016

Crystal structure of the ternary EcoRV-DNA-Lu complex with uncleaved DNA substrate. Lanthanide binding to EcoRV-DNA complex inhibits cleavage.
Descriptor:	1,2-ETHANEDIOL, DNA (5'-D(APAPAPGPAPTPAPTPCPTPTPT)-3'), LUTETIUM (III) ION, ...
Authors:	Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L.
Deposit date:	2015-12-09
Release date:	2016-11-09
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.76 Å)
Cite:	Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016