8A6J
| Nudaurelia capensis omega virus maturation intermediate captured at pH6.25 (insect cell expressed VLPs) | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-06-17 | 公開日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Decoding virus maturation with cryo-EM structures of intermediates To be published
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8A3C
| Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs) | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-06-08 | 公開日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs) To be published
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8AC6
| Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): medium class from symmetry expansion | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-07-05 | 公開日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Decoding virus maturation with cryo-EM structures of intermediates To be published
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8ACH
| Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): large class from symmetry expansion | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-07-05 | 公開日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Decoding virus maturation with cryo-EM structures of intermediates To be published
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8AAY
| Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): small class from symmetry expansion | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-07-04 | 公開日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Decoding virus maturation with cryo-EM structures of intermediates To be published
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7ZPC
| CDK2 in complex 9K-DOS | 分子名称: | Cyclin-dependent kinase 2, ~{N}-(1-methylpyrazol-4-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxamide | 著者 | Watt, J.E, Martin, M.P, Noble, M.E.N. | 登録日 | 2022-04-27 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Build-Couple-Transform: A Paradigm for Lead-like Library Synthesis with Scaffold Diversity. J.Med.Chem., 65, 2022
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8ABT
| Crystal structure of NaLdpA in complex with the product analog Resveratrol | 分子名称: | RESVERATROL, SULFATE ION, SnoaL-like domain-containing protein | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABU
| Crystal structure of NaLdpA mutant H97Q in complex with erythro-DGPD | 分子名称: | (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SnoaL-like domain-containing protein | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABV
| Crystal structure of SpLdpA in complex with erythro-DGPD | 分子名称: | (1R,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, GLYCEROL, ... | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABW
| Crystal structure of SpLdpA in complex with threo-DGPD | 分子名称: | (1R,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SULFATE ION, ... | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8A17
| Human PTPRM domains FN3-4, in spacegroup P3221 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ... | 著者 | Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E. | 登録日 | 2022-05-31 | 公開日 | 2023-03-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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8A1F
| Human PTPRK N-terminal domains MAM-Ig-FN1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. | 登録日 | 2022-06-01 | 公開日 | 2023-03-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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8A16
| Human PTPRM domains FN3-4, in spacegroup P212121 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E. | 登録日 | 2022-05-31 | 公開日 | 2023-03-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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8AFI
| GABARAP in complex with LIR motif of HsATG3 | 分子名称: | ACETATE ION, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ... | 著者 | Farnung, J, Benoit, R.M, Corn, J.E, Bode, J.W. | 登録日 | 2022-07-18 | 公開日 | 2023-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3. Acs Cent.Sci., 9, 2023
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8AYV
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8AIT
| Crystal structure of cutinase PbauzCut from Pseudomonas bauzanensis | 分子名称: | Cutinase, SULFATE ION | 著者 | Zahn, M, Allen, M.D, Pickford, A.R, McGeehan, J.E. | 登録日 | 2022-07-27 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering. ChemSusChem, 16, 2023
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8AIS
| Crystal structure of cutinase PsCut from Pseudomonas saudimassiliensis | 分子名称: | ACETATE ION, Lipase 1 | 著者 | Zahn, M, Allen, M.D, Pickford, A.R, McGeehan, J.E. | 登録日 | 2022-07-27 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering. ChemSusChem, 16, 2023
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8AIR
| Crystal structure of cutinase RgCutII from Rhizobacter gummiphilus | 分子名称: | ACETATE ION, RgCutII | 著者 | Zahn, M, Allen, M.D, Pickford, A.R, McGeehan, J.E. | 登録日 | 2022-07-27 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering. ChemSusChem, 16, 2023
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8AJ8
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8ARL
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8BVQ
| E. coli BAM complex (BamABCDE) bound to darobactin B | 分子名称: | Darobactin-B, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | 著者 | Horne, J.E, Fenn, K.L, Radford, S.E, Ranson, N.A. | 登録日 | 2022-12-05 | 公開日 | 2023-05-24 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CDQ
| Plasmodium falciparum Myosin A full-length, post-rigor state complexed to the inhibitor KNX-002 and Mg.ATP-gamma-S | 分子名称: | 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-~{N}-[(3-thiophen-2-yl-1~{H}-pyrazol-4-yl)methyl]cyclopropan-1-amine, GLYCEROL, ... | 著者 | Moussaoui, D, Robblee, J.P, Robert-Paganin, J, Auguin, D, Fisher, F, Fagnant, P.M, MacFarlane, J.E, Schaletzky, J, Wehri, E, Mueller-Dieckmann, C, Baum, J, Trybus, K.M, Houdusse, A. | 登録日 | 2023-01-31 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design. Nat Commun, 14, 2023
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8F48
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8CW2
| Crystal structure of TDP1 complexed with compound XZ760 | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-({(4R)-7-phenyl-2-[4-(2-{[4-(pyridin-2-yl)phenyl]methoxy}ethyl)phenyl]imidazo[1,2-a]pyridin-3-yl}amino)benzene-1,2-dicarboxylic acid, ... | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | 登録日 | 2022-05-18 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | 主引用文献 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification. Rsc Chem Biol, 4, 2023
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8CVQ
| Crystal structure of TDP1 complexed with compound XZ761 | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid, ... | 著者 | Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | 登録日 | 2022-05-18 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification. Rsc Chem Biol, 4, 2023
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