4LEI
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4LDP
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3TSA
| Spinosyn Rhamnosyltransferase SpnG | 分子名称: | MAGNESIUM ION, NDP-rhamnosyltransferase, alpha-D-glucopyranose | 著者 | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | 登録日 | 2011-09-12 | 公開日 | 2012-02-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
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3UYK
| Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone | 分子名称: | (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-2,13-dihydroxy-14-methyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-1H-as-indaceno[3,2-d]oxacyclododecine-7,15-dione, MAGNESIUM ION, NDP-rhamnosyltransferase, ... | 著者 | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | 登録日 | 2011-12-06 | 公開日 | 2012-02-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
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3UYL
| Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate | 分子名称: | MAGNESIUM ION, NDP-rhamnosyltransferase, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | 登録日 | 2011-12-06 | 公開日 | 2012-02-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG. Biochemistry, 51, 2012
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6VNA
| Pden_1323 | 分子名称: | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding protein | 著者 | Isiorho, E.A, Mansoorabadi, S.O. | 登録日 | 2020-01-29 | 公開日 | 2021-02-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A noncanonical heme oxygenase specific for the degradation of c-type heme. J.Biol.Chem., 296, 2021
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7SHQ
| Structure of a functional construct of eukaryotic elongation factor 2 kinase in complex with calmodulin. | 分子名称: | CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase, ... | 著者 | Piserchio, A, Isiorho, E.A, Jeruzalmi, D, Dalby, K.N, Ghose, R. | 登録日 | 2021-10-11 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase. Sci Adv, 8, 2022
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4PNE
| Crystal Structure of the [4+2]-Cyclase SpnF | 分子名称: | MALONATE ION, Methyltransferase-like protein, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Fage, C.D, Isiorho, E.A, Liu, Y.-N, Liu, H.-W, Keatinge-Clay, A.T. | 登録日 | 2014-05-23 | 公開日 | 2015-02-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition. Nat.Chem.Biol., 11, 2015
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8GM5
| Functional construct of the Eukaryotic elongation factor 2 kinase bound to Calmodulin, ADP and to the A-484954 inhibitor and showing two conformations for the 498-520 loop | 分子名称: | 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R. | 登録日 | 2023-03-24 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor. J.Biol.Chem., 299, 2023
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8GM4
| Functional construct of the Eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor | 分子名称: | 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R. | 登録日 | 2023-03-24 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor. J.Biol.Chem., 299, 2023
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8FNY
| Nucleotide-bound structure of a functional construct of eukaryotic elongation factor 2 kinase. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R. | 登録日 | 2022-12-28 | 公開日 | 2023-05-03 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin. Proc.Natl.Acad.Sci.USA, 120, 2023
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8FO6
| Nucleotide-free structure of a functional construct of eukaryotic elongation factor 2 kinase. | 分子名称: | CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase, ... | 著者 | Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R. | 登録日 | 2022-12-29 | 公開日 | 2023-05-03 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin. Proc.Natl.Acad.Sci.USA, 120, 2023
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7V6H
| Crystal Structure of the SpnL | 分子名称: | Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D. | 登録日 | 2021-08-20 | 公開日 | 2021-12-29 | 実験手法 | X-RAY DIFFRACTION (3.054 Å) | 主引用文献 | Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A. J.Am.Chem.Soc., 143, 2021
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8G4A
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