8GM4

Functional construct of the Eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor

Summary for 8GM4

Entry DOI	10.2210/pdb8gm4/pdb
Descriptor	Eukaryotic elongation factor 2 kinase, Calmodulin-1, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	elongation factor 2 kinase, eef2, eef2k, eef-2k, calmodulin, translation, a-484954, adp, allostery, translation-transferase complex, signaling protein, translation/transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	77964.13
Authors	Piserchio, A.,Isiorho, E.A.,Dalby, K.N.,Ghose, R. (deposition date: 2023-03-24, release date: 2023-05-31, Last modification date: 2023-10-25)
Primary citation	Piserchio, A.,Isiorho, E.A.,Dalby, K.N.,Ghose, R. Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor. J.Biol.Chem., 299:104813-104813, 2023 Cited by PubMed: 37172726 DOI: 10.1016/j.jbc.2023.104813 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation