4JC0
| Crystal structure of Thermotoga maritima holo RimO in complex with pentasulfide, Northeast Structural Genomics Consortium Target VR77 | 分子名称: | IRON/SULFUR PENTA-SULFIDE CONNECTED CLUSTERS, Ribosomal protein S12 methylthiotransferase RimO | 著者 | Forouhar, F, Hussain, M, Seetharaman, J, Fang, Y, Chen, C.X, Cunningham, K, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-20 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases. Nat.Chem.Biol., 9, 2013
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4JGK
| Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 | 分子名称: | evolved variant of a designed serine hydrolase | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-03-01 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.883 Å) | 主引用文献 | Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 To be Published
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4JXI
| Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184 | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, BROMIDE ION, GLYCEROL, ... | 著者 | Kuzin, A, Smith, M.D, Richter, F, Lew, S, Seetharaman, R, Bryan, C, Lech, Z, Kiss, G, Moretti, R, Maglaqui, M, Xiao, R, Kohan, E, Smith, M, Everett, J.K, Nguyen, R, Pande, V, Hilvert, D, Kornhaber, G, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-03-28 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184 To be Published
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4JBC
| Crystal Structure of the computationally designed serine hydrolase 3mmj_2, Northeast Structural Genomics Consortium (NESG) Target OR318 | 分子名称: | PHOSPHATE ION, designed serine hydrolase 3mmj_2 | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Baker, D, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-19 | 公開日 | 2013-03-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | Crystal Structure of the computationally designed serine hydrolase 3mmj_2, Northeast Structural Genomics Consortium (NESG) Target OR318 To be Published
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4J4Z
| Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Designed serine hydrolase variant OSH55.4_H1.2, ... | 著者 | Kuzin, A.P, Lew, S, Rajagopalan, S, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-07 | 公開日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 To be Published
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4JCA
| Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273 | 分子名称: | CITRIC ACID, RUBIDIUM ION, serine hydrolase | 著者 | Kuzin, A.P, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-02-21 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | 主引用文献 | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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4JLL
| Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Tong, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-03-12 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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4K0C
| Crystal Structure of the computationally designed serine hydrolase. Northeast Structural Genomics Consortium (NESG) Target OR317 | 分子名称: | designed serine hydrolase | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-03 | 公開日 | 2013-04-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR317 To be Published
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4KAA
| Crystal structure of the halotag2 protein at the resolution 2.3A, Northeast Structural Genomics Consortium (NESG) target OR150 | 分子名称: | DI(HYDROXYETHYL)ETHER, Haloalkane dehalogenase, SODIUM ION | 著者 | Kuzin, A, Lew, S, Neklesa, T.K, Noblin, D, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Crews, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-22 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.276 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR150 To be Published
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4KAJ
| X-Ray Structure of the complex of Haloalkane dehalogenase HaloTag7 with HALTS, Northeast Structural Genomics Consortium (NESG) Target OR151 | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Kuzin, A, Lew, S, Neklesa, T.K, Noblin, D, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Crews, C.M, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-22 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR151 To be Published
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4KAC
| X-Ray Structure of the complex HaloTag2 with HALTS. Northeast Structural Genomics Consortium (NESG) Target OR150. | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, AMMONIUM ION, Haloalkane dehalogenase, ... | 著者 | Kuzin, A, Lew, S, Neklesa, T.K, Noblin, D, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Crews, C.M, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-22 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.223 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR150 To be Published
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4KYV
| Crystal Structure of dehalogenase HaloTag2 with HALTS at the resolution 1.8A. Northeast Structural Genomics Consortium (NESG) Target OR150 | 分子名称: | N-(2-ethoxy-3,5-dimethylbenzyl)-1H-tetrazol-5-amine, SODIUM ION, dehalogenase HaloTag2 | 著者 | Kuzin, A, Lew, S, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, H, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR150 To be Published
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4KYZ
| Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327 | 分子名称: | Designed protein OR327 | 著者 | Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.492 Å) | 主引用文献 | Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
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4L1J
| Three dimensional structure of mutant D143A of human HD domain-containing protein 2, Northeast Structural Genomics Consortium (NESG) Target HR6723 | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, HD domain-containing protein 2, ... | 著者 | Kuzin, A, Su, M, Yakunin, A, Beloglazova, O, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Brown, G, Flick, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-06-03 | 公開日 | 2013-06-19 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.824 Å) | 主引用文献 | Three dimensional structure of mutant D143A of human HD
domain-containing protein 2, Northeast Structural Genomics Consortium (NESG) Target HR6723 To be Published
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4KYB
| Crystal Structure of de novo designed serine hydrolase OSH55.14_E3, Northeast Structural Genomics Consortium Target OR342 | 分子名称: | Designed Protein OR342, PHOSPHATE ION | 著者 | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Lee, D, Raja, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-28 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.909 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR342 To be Published
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4L7W
| Crystal structure mutant H77A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 | 分子名称: | HD domain-containing protein 2, MAGNESIUM ION | 著者 | Kuzin, A, Su, M, Yakunin, A, Beloglazova, N, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Brown, G, Flick, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-06-14 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.305 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target HR6723 To be Published
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4KY3
| Three-dimensional Structure of the orthorhombic crystal of computationally designed insertion domain , Northeast Structural Genomics Consortium (NESG) Target OR327 | 分子名称: | designed protein OR327 | 著者 | Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-28 | 公開日 | 2013-06-19 | 最終更新日 | 2016-02-17 | 実験手法 | X-RAY DIFFRACTION (2.964 Å) | 主引用文献 | Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
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4L6E
| Crystal Structure of the RanBD1 fourth domain of E3 SUMO-protein ligase RanBP2. Northeast Structural Genomics Consortium (NESG) Target HR9193b | 分子名称: | E3 SUMO-protein ligase RanBP2 | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Mao, L, Xiao, R, Maglaqui, M, Kogan, S, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-06-12 | 公開日 | 2013-06-26 | 実験手法 | X-RAY DIFFRACTION (2.496 Å) | 主引用文献 | Crystal Structure of the RanBD1 fourth domain of E3 SUMO-protein ligase RanBP2. To be Published
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4L0R
| Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A. | 分子名称: | Centrosomal protein of 57 kDa | 著者 | Seetharaman, J, Lew, S, Su, M, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-31 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics consortium id HR9027A To be Published
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4L7E
| Three dimensional structure of mutant D78A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, HD domain-containing protein 2, ... | 著者 | Kuzin, A, Su, M, Yakunin, A, Beloglazova, N, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Brown, G, Flick, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-06-13 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.229 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target HR6723 To be Published
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4LNY
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 | 分子名称: | CADMIUM ION, CHLORIDE ION, Engineered Protein OR422 | 著者 | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Sahdev, S, Xiao, R, Maglaqui, M, Kogan, S, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-07-12 | 公開日 | 2013-08-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | 主引用文献 | Crystal Structure of Engineered Protein OR422. To be Published
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4LOA
| X-ray structure of the de-novo design amidase at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target OR398 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, De-novo design amidase | 著者 | Kuzin, A, Lew, S, Vorobiev, S.M, Seetharaman, J, Sahdev, S, Xiao, R, Maglaqui, M, Kogan, S, Khersonsky, O, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-07-12 | 公開日 | 2013-08-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target OR398 To be Published
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4LT9
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR404 | 分子名称: | Engineered Protein OR404 | 著者 | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Sahdev, S, Xiao, R, Kogan, S, Maglaqui, M, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-07-23 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of Engineered Protein OR404. To be Published
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4N6C
| Crystal Structure of the B1RZQ2 protein from Streptococcus pneumoniae. Northeast Structural Genomics Consortium (NESG) Target SpR36. | 分子名称: | BROMIDE ION, uncharacterized protein | 著者 | Vorobiev, S, Seetharaman, J, Patel, D, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-11 | 公開日 | 2013-10-30 | 実験手法 | X-RAY DIFFRACTION (1.548 Å) | 主引用文献 | Crystal Structure of the B1RZQ2 protein from Streptococcus pneumoniae. To be Published
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4N9X
| Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 | 分子名称: | Putative monooxygenase | 著者 | Kuzin, A, Chen, Y, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Owens, L.A, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-21 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 To be Published
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