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5WH1
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BU of 5wh1 by Molmil
Apo form of the C-terminal region of human Transcription Factor IIB
Descriptor: SULFATE ION, Transcription initiation factor IIB
Authors:Bratkowski, M.A, Liu, X.
Deposit date:2017-07-14
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.
J. Biol. Chem., 293, 2018
5GHY
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BU of 5ghy by Molmil
Crystal structure of beta-lactamase PenP mutant-E166H in complex with cephaloridine as "post-acylation" intermediate
Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase
Authors:Pan, X, Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
4WRS
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BU of 4wrs by Molmil
Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor.
Descriptor: 3-{6-[(4R)-6-azaspiro[2.5]oct-4-yloxy]pyrazin-2-yl}-5-(2,6-difluorophenyl)-1H-indazole, GLYCEROL, Serine/threonine-protein kinase pim-1
Authors:Mohr, C.
Deposit date:2014-10-25
Release date:2015-02-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
5GHZ
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BU of 5ghz by Molmil
Crystal structure of beta-lactamase PenP mutant-E166H in complex with cephaloridine as "pre-deacylation" intermediate
Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase
Authors:Pan, X, Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
5GHX
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BU of 5ghx by Molmil
Crystal structure of beta-lactamase PenP mutant-E166H
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Beta-lactamase
Authors:Pan, X, Zhao, Y.
Deposit date:2016-06-21
Release date:2017-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
4XGY
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BU of 4xgy by Molmil
GFP based antibody (fluorobody)
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Green fluorescent protein, mAb LCDR3
Authors:Shi, N, Chen, Y.G, Wang, S.H.
Deposit date:2015-01-03
Release date:2015-07-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:The structure of a GFP-based antibody (fluorobody) to TLH, a toxin from Vibrio parahaemolyticus.
Acta Crystallogr.,Sect.F, 71, 2015
7TJE
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BU of 7tje by Molmil
Bacteriophage Q beta capsid protein A38K
Descriptor: Minor capsid protein A1
Authors:Jin, X.
Deposit date:2022-01-16
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Alternative Assembly of Q beta Virus-like Particles
To Be Published
7TJM
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BU of 7tjm by Molmil
Bacteriophage Q beta capsid protein in T3 symmetry
Descriptor: Minor capsid protein A1
Authors:Jin, X.
Deposit date:2022-01-16
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Alternative Assembly of Q beta Virus-like Particles
To Be Published
7TJD
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BU of 7tjd by Molmil
Bacteriophage Q beta capsid protein in T1 symmetry
Descriptor: Minor capsid protein A1
Authors:Jin, X.
Deposit date:2022-01-16
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Alternative Assembly of Q beta Virus-like Particles
To Be Published
7TJG
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BU of 7tjg by Molmil
Bacteriophage Q beta capsid protein, A38K/A40C/D102C in T1 symmetry
Descriptor: Minor capsid protein A1
Authors:Jin, X.
Deposit date:2022-01-16
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.903 Å)
Cite:Alternative Assembly of Q beta Virus-like Particles
To Be Published
4YRB
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BU of 4yrb by Molmil
mouse TDH mutant R180K with NAD+ bound
Descriptor: L-threonine 3-dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, C, Li, F.
Deposit date:2015-03-14
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
4YRA
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BU of 4yra by Molmil
mouse TDH in the apo form
Descriptor: L-threonine 3-dehydrogenase, mitochondrial
Authors:He, C, Li, F.
Deposit date:2015-03-14
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
4YR9
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BU of 4yr9 by Molmil
mouse TDH with NAD+ bound
Descriptor: GLYCEROL, L-threonine 3-dehydrogenase, mitochondrial, ...
Authors:He, C, Li, F.
Deposit date:2015-03-14
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
5J8V
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BU of 5j8v by Molmil
Structure of rabbit ryanodine receptor RyR1 open state activated by calcium ion
Descriptor: Ryanodine receptor 1
Authors:Wang, X, Wei, R, Yin, C, Sun, F.
Deposit date:2016-04-08
Release date:2016-09-14
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1
Cell Res., 26, 2016
8DKF
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BU of 8dkf by Molmil
Antibody DH1030.1 Fab fragment
Descriptor: DH1030.1 Heavy chain, DH1030.1 Light chain
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:DH1030.1 glycan reactive Ab
To Be Published
7DTD
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BU of 7dtd by Molmil
Voltage-gated sodium channel Nav1.1 and beta4
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 1 subunit alpha, ...
Authors:Yan, N, Pan, X, Li, Z, Huang, G.
Deposit date:2021-01-04
Release date:2021-04-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Comparative structural analysis of human Na v 1.1 and Na v 1.5 reveals mutational hotspots for sodium channelopathies.
Proc.Natl.Acad.Sci.USA, 118, 2021
5JFB
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BU of 5jfb by Molmil
Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163
Descriptor: Scavenger receptor cysteine-rich type 1 protein M130
Authors:Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R.
Deposit date:2016-04-19
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
5UEW
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BU of 5uew by Molmil
BRD2 Bromodomain2 with A-1360579
Descriptor: Bromodomain-containing protein 2, N-[3-(4-methoxy-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-phenoxyphenyl]methanesulfonamide
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5UEY
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BU of 5uey by Molmil
BRD4_BD2_A-1412838
Descriptor: 5-[2-(2,4-difluorophenoxy)-5-{[ethyl(dihydroxy)-lambda~4~-sulfanyl]amino}phenyl]-4-ethoxy-1-methylpyridin-2(1H)-one, Bromodomain-containing protein 4
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5UEX
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BU of 5uex by Molmil
BRD4_BD2_A-1497627
Descriptor: 17-{[ethyl(dihydroxy)-lambda~4~-sulfanyl]amino}-11,13-difluoro-2-methyl-6,7,8,9-tetrahydrodibenzo[4,5:7,8][1,6]dioxacyclododecino[3,2-c]pyridin-3(2H)-one, Bromodomain-containing protein 4
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-05-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5UEU
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BU of 5ueu by Molmil
BRD4_BD2_A-1107604
Descriptor: Bromodomain-containing protein 4, methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-05-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5UF0
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BU of 5uf0 by Molmil
BRD4_BD2-A-35165
Descriptor: 2-methyl-5-(methylamino)-6-phenylpyridazin-3(2H)-one, Bromodomain-containing protein 4
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-06-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5UEZ
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BU of 5uez by Molmil
BRD4_BD2_A-1342843
Descriptor: 5-methoxy-2-methyl-6-(2-phenoxyphenyl)pyridazin-3(2H)-one, Bromodomain-containing protein 4
Authors:Park, C.H.
Deposit date:2017-01-03
Release date:2017-05-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.
J. Med. Chem., 60, 2017
5H3J
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BU of 5h3j by Molmil
Crystal structure of Grasp domain of Grasp55 complexed with the Golgin45 C-terminus
Descriptor: Golgi reassembly-stacking protein 2, Golgin-45, ZINC ION
Authors:Shi, N, Zhao, J, Li, B.
Deposit date:2016-10-25
Release date:2017-01-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural Basis for the Interaction between Golgi Reassembly-stacking Protein GRASP55 and Golgin45
J. Biol. Chem., 292, 2017
2PPH
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BU of 2pph by Molmil
solution structure of human MEKK3 PB1 domain
Descriptor: Mitogen-activated protein kinase kinase kinase 3
Authors:Hu, Q, Zhang, J, Wu, J, Shi, Y.
Deposit date:2007-04-30
Release date:2007-05-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Insight into the Binding Properties of MEKK3 PB1 to MEK5 PB1 from Its Solution Structure.
Biochemistry, 46, 2007

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