6KHP
| Crystal structure of Oryza sativa TDC with PLP and tryptamine | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, ACETATE ION, CALCIUM ION, ... | 著者 | Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. | 登録日 | 2019-07-16 | 公開日 | 2020-07-15 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis. J Adv Res, 24, 2020
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6NJD
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6NII
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8HMD
| base module state 2 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HMF
| head module state 2 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HMC
| base module state 1 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HME
| head module state 1 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8JBJ
| Crystal structure of anti-PVRIG Fab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Li, X.L, Song, J. | 登録日 | 2023-05-09 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity. Mabs, 15, 2023
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8JEL
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8JEO
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8JEQ
| Crystal structure of Tiragolumab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 2024
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8JEN
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8JEP
| Crystal structure of Ociperlimab | 分子名称: | antibody heavy chain, antibody light chain | 著者 | Sun, J, Zhang, X.X, Song, J. | 登録日 | 2023-05-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 2024
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1HTV
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6AHU
| Cryo-EM structure of human Ribonuclease P with mature tRNA | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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6AHV
| Crystal structure of human RPP40 | 分子名称: | Ribonuclease P protein subunit p40 | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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6AHR
| Cryo-EM structure of human Ribonuclease P | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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7FAY
| Crystal structure of SARS-CoV-2 main protease in complex with (R)-1a | 分子名称: | (2~{R})-~{N}-[(1~{R})-2-(~{tert}-butylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-~{N}-(4-~{tert}-butylphenyl)-2-oxidanyl-propanamide, 3C-like proteinase | 著者 | Zeng, R, Quan, B.X, Liu, X.L, Lei, J. | 登録日 | 2021-07-08 | 公開日 | 2021-07-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An orally available M pro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron. Nat Microbiol, 7, 2022
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7FAZ
| Crystal structure of the SARS-CoV-2 main protease in complex with Y180 | 分子名称: | (2~{R})-~{N}-dibenzofuran-3-yl-~{N}-[(1~{R})-2-[[(1~{S})-1-(4-fluorophenyl)ethyl]amino]-2-oxidanylidene-1-pyridin-3-yl-ethyl]-2-oxidanyl-propanamide, 3C-like proteinase, SODIUM ION | 著者 | Zeng, R, Quan, B.X, Liu, X.L, Lei, J. | 登録日 | 2021-07-08 | 公開日 | 2021-07-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An orally available M pro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron. Nat Microbiol, 7, 2022
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7DGW
| De novo designed protein H4A2S | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, de novo designed protein H4A2S | 著者 | Xu, Y, Liao, S, Chen, Q, Liu, H. | 登録日 | 2020-11-12 | 公開日 | 2021-11-24 | 最終更新日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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7DGU
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7DMF
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7DKK
| De novo design protein XM2H | 分子名称: | De novo design protein XM2H | 著者 | Bin, H. | 登録日 | 2020-11-24 | 公開日 | 2021-12-08 | 最終更新日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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7DKO
| De novo design protein AM2M | 分子名称: | de novo designed protein AM2M | 著者 | Bin, H. | 登録日 | 2020-11-25 | 公開日 | 2021-12-08 | 最終更新日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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7DGY
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