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6UH5
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BU of 6uh5 by Molmil
Structural basis of COMPASS eCM recognition of the H2Bub nucleosome
Descriptor: Bre2, DNA (146-MER), H3 N-terminus, ...
Authors:Hsu, P.L, Shi, H, Zheng, N.
Deposit date:2019-09-26
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
6CHG
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BU of 6chg by Molmil
Crystal structure of the yeast COMPASS catalytic module
Descriptor: H3, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ...
Authors:Hsu, P.L, Li, H, Zheng, N.
Deposit date:2018-02-22
Release date:2018-08-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.985 Å)
Cite:Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.
Cell, 174, 2018
6UGM
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BU of 6ugm by Molmil
Structural basis of COMPASS eCM recognition of an unmodified nucleosome
Descriptor: Bre2, DNA (146-MER), H3 N-terminus, ...
Authors:Hsu, P.L, Shi, H, Zheng, N.
Deposit date:2019-09-26
Release date:2019-11-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
4M3O
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BU of 4m3o by Molmil
Crystal structure of K.lactis Rtr1 NTD
Descriptor: KLLA0F12672p, ZINC ION
Authors:Hsu, P.L, Yang, W, Zheng, N, Varani, G.
Deposit date:2013-08-06
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
6EEY
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BU of 6eey by Molmil
Crystal structure of human Scribble PDZ4 R1110G Mutant
Descriptor: Protein scribble homolog
Authors:Janezic, E.M, Hsu, P, Hague, C.
Deposit date:2018-08-15
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.145 Å)
Cite:Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands.
Sci Rep, 9, 2019
6B3X
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BU of 6b3x by Molmil
Crystal structure of CstF-50 in complex with CstF-77
Descriptor: Cleavage stimulation factor subunit 1, Cleavage stimulation factor subunit 3
Authors:Yang, W, Hsu, P, Yang, F, Song, J.E, Varani, G.
Deposit date:2017-09-25
Release date:2017-11-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.
Nucleic Acids Res., 46, 2018
6OF7
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BU of 6of7 by Molmil
Crystal structure of the CRY1-PER2 complex
Descriptor: Cryptochrome-1, Period circadian protein homolog 2
Authors:Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L.
Deposit date:2019-03-28
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Elife, 9, 2020
7SZR
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BU of 7szr by Molmil
NIK bound to inhibitor G02792917
Descriptor: 1-(3-{[(1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2-azabicyclo[3.1.0]hexan-4-yl]ethynyl}phenyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION
Authors:Liau, N.P.D, Hymowitz, S.G.
Deposit date:2021-11-29
Release date:2023-06-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
Bioorg.Med.Chem.Lett., 89, 2023

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