5VYR
| Crystal structure of the WbkC formyl transferase from Brucella melitensis | Descriptor: | (6R)-2-amino-6-methyl-5,6,7,8-tetrahydropteridin-4(3H)-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Riegert, A.S, Chantigian, D.P, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-05-26 | Release date: | 2017-07-05 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis. Biochemistry, 56, 2017
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5UIN
| X-ray structure of the W305A variant of the FdtF N-formyltransferase from salmonella enteric O60 | Descriptor: | CHLORIDE ION, Formyltransferase, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | Authors: | Woodford, C.R, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-01-14 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular architecture of an N-formyltransferase from Salmonella enterica O60. J. Struct. Biol., 200, 2017
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5UIL
| X-ray structure of the FdtF N-formyltransferase from Salmonella enterica O60 in complex with TDP-Fuc3N and tetrahydrofolate | Descriptor: | (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, Formyltransferase, N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... | Authors: | Woodford, C.R, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-01-14 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular architecture of an N-formyltransferase from Salmonella enterica O60. J. Struct. Biol., 200, 2017
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5TIC
| X-ray structure of wild-type E. coli Acyl-CoA thioesterase I at pH 5 | Descriptor: | Acyl-CoA thioesterase I, CHLORIDE ION | Authors: | Thoden, J.B, Holden, H.M, Grisewood, M.J, Hernandez Lozada, N.J, Gifford, N.P, Mendez-Perez, D, Schoenberger, H.A, Allan, M.F, Pfleger, B.F, Marines, C.D. | Deposit date: | 2016-10-02 | Release date: | 2017-04-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Computational Redesign of Acyl-ACP Thioesterase with Improved Selectivity toward Medium-Chain-Length Fatty Acids. ACS Catal, 7, 2017
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5TID
| X-ray structure of acyl-CoA thioesterase I, TesA, mutant M141L/Y145K/L146K at pH 5 in complex with octanoic acid | Descriptor: | Acyl-CoA thioesterase I, OCTANOIC ACID (CAPRYLIC ACID) | Authors: | Thoden, J.B, Holden, H.M, Grisewood, M.J, Hernandez Lozada, N.J, Gifford, N.P, Mendez-Perez, D, Schoenberger, H.A, Allan, M.F, Pfleger, B.F, Marines, C.D. | Deposit date: | 2016-10-02 | Release date: | 2017-04-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Computational Redesign of Acyl-ACP Thioesterase with Improved Selectivity toward Medium-Chain-Length Fatty Acids. ACS Catal, 7, 2017
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5VYT
| Crystal structure of the WbkC N-formyltransferase (F142A variant) from Brucella melitensis | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase, ... | Authors: | Riegert, A.S, Chantigian, D.P, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-05-26 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis. Biochemistry, 56, 2017
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5W71
| X-ray structure of BtrR from Bacillus circulans in the presence of the 2-DOS external aldimine | Descriptor: | CHLORIDE ION, L-glutamine:2-deoxy-scyllo-inosose aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Zachman-Brockmeyer, T.R, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-06-19 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin. Protein Sci., 26, 2017
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5VYU
| Crystal structure of the WbkC N-formyltransferase from Brucella melitensis in complex with GDP-perosaminea and N-10-formyltetrahydrofolate | Descriptor: | GDP-perosamine, GUANOSINE-5'-DIPHOSPHATE, Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase, ... | Authors: | Riegert, A.S, Chantigian, D.P, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-05-26 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis. Biochemistry, 56, 2017
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7JID
| Crystal structure of the L780 UDP-rhamnose synthase from Acanthamoeba polyphaga mimivirus | Descriptor: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-L-Rhamnose Synthase, ... | Authors: | Bockhaus, N.J, Ferek, J.D, Thoden, J.B, Holden, H.M. | Deposit date: | 2020-07-23 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The high-resolution structure of a UDP-L-rhamnose synthase from Acanthamoeba polyphaga Mimivirus. Protein Sci., 29, 2020
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1JDB
| CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE, CHLORIDE ION, ... | Authors: | Thoden, J.B, Holden, H.M, Wesenberg, G, Raushel, F.M, Rayment, I. | Deposit date: | 1997-03-25 | Release date: | 1998-06-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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1PTA
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1MMD
| TRUNCATED HEAD OF MYOSIN FROM DICTYOSTELIUM DISCOIDEUM COMPLEXED WITH MGADP-BEF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Fisher, A.J, Holden, H.M, Rayment, I. | Deposit date: | 1995-03-21 | Release date: | 1996-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-. Biochemistry, 34, 1995
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1CE8
| CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, INOSINIC ACID, ... | Authors: | Thoden, J.B, Raushel, F.M, Holden, H.M. | Deposit date: | 1999-03-18 | Release date: | 1999-07-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The binding of inosine monophosphate to Escherichia coli carbamoyl phosphate synthetase. J.Biol.Chem., 274, 1999
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1CS0
| Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... | Authors: | Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. | Deposit date: | 1999-08-16 | Release date: | 1999-12-10 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
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1DV1
| STRUCTURE OF BIOTIN CARBOXYLASE (APO) | Descriptor: | BIOTIN CARBOXYLASE, PHOSPHATE ION | Authors: | Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. | Deposit date: | 2000-01-19 | Release date: | 2000-06-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
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1DPM
| THREE-DIMENSIONAL STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE WITH BOUND SUBSTRATE ANALOG DIETHYL 4-METHYLBENZYLPHOSPHONATE | Descriptor: | DIETHYL 4-METHYLBENZYLPHOSPHONATE, FORMIC ACID, PHOSPHOTRIESTERASE, ... | Authors: | Vanhooke, J.L, Benning, M.M, Raushel, F.M, Holden, H.M. | Deposit date: | 1996-02-13 | Release date: | 1997-08-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of the zinc-containing phosphotriesterase with the bound substrate analog diethyl 4-methylbenzylphosphonate. Biochemistry, 35, 1996
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1EF9
| THE CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE COMPLEXED WITH 2S-CARBOXYPROPYL COA | Descriptor: | 2-CARBOXYPROPYL-COENZYME A, METHYLMALONYL COA DECARBOXYLASE | Authors: | Benning, M.M, Haller, T, Gerlt, J.A, Holden, H.M. | Deposit date: | 2000-02-07 | Release date: | 2000-05-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli. Biochemistry, 39, 2000
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1EK6
| STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, TETRAMETHYLAMMONIUM ION, ... | Authors: | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | Deposit date: | 2000-03-06 | Release date: | 2000-05-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase. Biochemistry, 39, 2000
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1DV2
| The structure of biotin carboxylase, mutant E288K, complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE | Authors: | Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. | Deposit date: | 2000-01-19 | Release date: | 2000-06-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
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1FRD
| MOLECULAR STRUCTURE OF THE OXIDIZED, RECOMBINANT, HETEROCYST (2FE-2S) FERREDOXIN FROM ANABAENA 7120 DETERMINED TO 1.7 ANGSTROMS RESOLUTION | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, HETEROCYST [2FE-2S] FERREDOXIN | Authors: | Jacobson, B.L, Chae, Y.K, Markley, J.L, Rayment, I, Holden, H.M. | Deposit date: | 1993-04-14 | Release date: | 1994-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular structure of the oxidized, recombinant, heterocyst [2Fe-2S] ferredoxin from Anabaena 7120 determined to 1.7-A resolution. Biochemistry, 32, 1993
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1FMV
| CRYSTAL STRUCTURE OF THE APO MOTOR DOMAIN OF DICTYOSTELLIUM MYOSIN II | Descriptor: | CHLORIDE ION, MYOSIN II HEAVY CHAIN | Authors: | Bauer, C.B, Holden, H.M, Thoden, J.B, Smith, R, Rayment, I. | Deposit date: | 2000-08-18 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain. J.Biol.Chem., 275, 2000
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1EK5
| STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE IN COMPLEX WITH NAD+ | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE 4-EPIMERASE | Authors: | Thoden, J.B, Wohlers, T.M, Fridovich-Keil, J.L, Holden, H.M. | Deposit date: | 2000-03-06 | Release date: | 2000-05-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase. Biochemistry, 39, 2000
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1FMW
| CRYSTAL STRUCTURE OF THE MGATP COMPLEX FOR THE MOTOR DOMAIN OF DICTYOSTELIUM MYOSIN II | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MYOSIN II HEAVY CHAIN | Authors: | Bauer, C.B, Holden, H.M, Thoden, J.B, Smith, R, Rayment, I. | Deposit date: | 2000-08-18 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain. J.Biol.Chem., 275, 2000
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1BSL
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1BXG
| PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND BETA-PHENYLPROPIONATE | Descriptor: | HYDROCINNAMIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHENYLALANINE DEHYDROGENASE, ... | Authors: | Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. | Deposit date: | 1998-10-02 | Release date: | 1999-05-18 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism. Biochemistry, 38, 1999
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