5VYT

Crystal structure of the WbkC N-formyltransferase (F142A variant) from Brucella melitensis

Summary for 5VYT

• Entry DOI: 10.2210/pdb5vyt/pdb
• Related: 5vyr 5vys
• Descriptor: Gdp-mannose 4,6-dehydratase / gdp-4-amino-4,6-dideoxy-d-mannose formyltransferase, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: brucellosis, deoxysugar, transferase
• Biological source: Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
• Total number of polymer chains: 4
• Total formula weight: 120679.68

Authors

Riegert, A.S.,Chantigian, D.P.,Thoden, J.B.,Holden, H.M. (deposition date: 2017-05-26, release date: 2017-07-05, Last modification date: 2023-10-04)

• Primary citation: Riegert, A.S.,Chantigian, D.P.,Thoden, J.B.,Tipton, P.A.,Holden, H.M.; Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis.; Biochemistry, 56:3657-3668, 2017; PubMed: 28636341; DOI: 10.1021/acs.biochem.7b00494

Experimental method

X-RAY DIFFRACTION (2.2 Å)