1DS4
| CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, PH 6, 100K | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | 登録日 | 2000-01-07 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
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1DSG
| CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 5, ROOM TEMPERATURE. | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | 登録日 | 2000-01-07 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
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1DSP
| CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 7, ROOM TEMPERATURE. | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | 登録日 | 2000-01-07 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
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1DSE
| CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, WITH PHOSPHATE BOUND, PH 6, 100K | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PHOSPHATE ION, ... | 著者 | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | 登録日 | 2000-01-07 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
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1DSO
| CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 6, ROOM TEMPERATURE. | 分子名称: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | 登録日 | 2000-01-07 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
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1DJ1
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1DJ5
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6YJ4
| Structure of Yarrowia lipolytica complex I at 2.7 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | 著者 | Hirst, J, Grba, D. | 登録日 | 2020-04-02 | 公開日 | 2020-08-12 | 最終更新日 | 2021-03-17 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation. Nat.Struct.Mol.Biol., 27, 2020
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6YJ5
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7B0N
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5COD
| Bovine heart complex I membrane domain | 分子名称: | NADH-ubiquinone oxidoreductase chain 4, NADH-ubiquinone oxidoreductase chain 5, SDAP, ... | 著者 | Zhu, J, Hirst, J, King, M.S, Yu, M, Leslie, A.G.W, Klipcan, L. | 登録日 | 2015-07-20 | 公開日 | 2015-09-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (6.74 Å) | 主引用文献 | Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments. Proc.Natl.Acad.Sci.USA, 112, 2015
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7B93
| Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ... | 著者 | Chung, I, Hirst, J. | 登録日 | 2020-12-14 | 公開日 | 2021-05-26 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Cork-in-bottle mechanism of inhibitor binding to mammalian complex I. Sci Adv, 7, 2021
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4UQ8
| Electron cryo-microscopy of bovine Complex I | 分子名称: | ACYL CARRIER PROTEIN, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Vinothkumar, K.R, Zhu, J, Hirst, J. | 登録日 | 2014-06-21 | 公開日 | 2014-10-01 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4.95 Å) | 主引用文献 | Architecture of Mammalian Respiratory Complex I. Nature, 515, 2014
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2V07
| Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant | 分子名称: | CYTOCHROME C6, HEME C | 著者 | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | 登録日 | 2007-05-09 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Modulation of heme redox potential in the cytochrome c6 family. J. Am. Chem. Soc., 129, 2007
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2V08
| Structure of wild-type Phormidium laminosum cytochrome c6 | 分子名称: | CHLORIDE ION, CYTOCHROME C6, HEME C, ... | 著者 | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | 登録日 | 2007-05-10 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Modulation of heme redox potential in the cytochrome c6 family. J. Am. Chem. Soc., 129, 2007
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8BA0
| Drosophila melanogaster complex I in the Twisted state (Dm2) | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | 著者 | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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8B9Z
| Drosophila melanogaster complex I in the Active state (Dm1) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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8C2S
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2022-12-22 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA4
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain). | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA5
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 3). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA3
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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8CA1
| Cryo-EM structure of the ACADVL dimer from Mus musculus. | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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7QSD
| Bovine complex I in the active state at 3.1 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-03-02 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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5O31
| Mitochondrial complex I in the deactive state | 分子名称: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Blaza, J.N, Vinothkumar, K.R, Hirst, J. | 登録日 | 2017-05-23 | 公開日 | 2018-01-17 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Structure of the Deactive State of Mammalian Respiratory Complex I. Structure, 26, 2018
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7R42
| Bovine complex I in the presence of IM1761092, active class ii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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