2BZM
| Solution structure of the primary host recognition region of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N. | 登録日 | 2005-08-18 | 公開日 | 2006-03-22 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure. J.Biol.Chem., 281, 2006
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4AXP
| NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. | 分子名称: | 12 KDA HEAT SHOCK PROTEIN | 著者 | Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A. | 登録日 | 2012-06-13 | 公開日 | 2012-08-08 | 最終更新日 | 2018-01-24 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast. Plos One, 7, 2012
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2JGX
| Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y) | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | 登録日 | 2007-02-16 | 公開日 | 2007-03-20 | 最終更新日 | 2018-05-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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2JGW
| Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H) | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | 登録日 | 2007-02-16 | 公開日 | 2007-03-20 | 最終更新日 | 2018-05-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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3OXU
| Complement components factor H CCP19-20 and C3d in complex | 分子名称: | Complement C3, GLYCEROL, HF protein | 著者 | Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. | 登録日 | 2010-09-22 | 公開日 | 2011-02-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for engagement by complement factor H of C3b on a self surface. Nat.Struct.Mol.Biol., 18, 2011
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3R62
| Structure of complement regulator Factor H mutant, T1184R. | 分子名称: | Complement factor H, GLYCEROL | 著者 | Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P. | 登録日 | 2011-03-21 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Crystallographic determination of the disease-associated T1184R variant of the complement Factor H. Acta Crystallogr.,Sect.D, 67, 2011
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2V8E
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ... | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | 登録日 | 2007-08-07 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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4B2S
| Solution structure of CCP modules 11-12 of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | 登録日 | 2012-07-17 | 公開日 | 2012-10-17 | 最終更新日 | 2013-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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4B2R
| Solution structure of CCP modules 10-11 of complement factor H | 分子名称: | COMPLEMENT FACTOR H | 著者 | Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. | 登録日 | 2012-07-17 | 公開日 | 2012-10-10 | 最終更新日 | 2019-09-25 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
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2KMS
| Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | 分子名称: | Complement factor H | 著者 | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | 登録日 | 2009-08-04 | 公開日 | 2009-11-03 | 最終更新日 | 2020-02-26 | 実験手法 | SOLUTION NMR | 主引用文献 | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module J.Mol.Biol., 395, 2010
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2KMG
| The structure of the KlcA and ArdB proteins show a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro | 分子名称: | KlcA | 著者 | Serfiotis-Mitsa, D, Herbert, A.P, Roberts, G.A, Soares, D.C, White, J.H, Blakely, G.W, Uhrin, D, Dryden, D.T.F. | 登録日 | 2009-07-28 | 公開日 | 2009-12-29 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro Nucleic Acids Res., 38, 2010
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2LV7
| Solution structure of Ca2+-bound CaBP7 N-terminal doman | 分子名称: | CALCIUM ION, Calcium-binding protein 7 | 著者 | Mccue, H.V, Patel, P, Herbert, A.P, Lian, L, Burgoyne, R.D, Haynes, L.P. | 登録日 | 2012-06-29 | 公開日 | 2012-09-26 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the Ca2+-bound N-terminal Domain of CaBP7: A REGULATOR OF GOLGI TRAFFICKING. J.Biol.Chem., 287, 2012
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2RLQ
| NMR structure of CCP modules 2-3 of complement factor H | 分子名称: | Complement factor H | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | 登録日 | 2007-07-29 | 公開日 | 2008-02-19 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2RLP
| NMR structure of CCP modules 1-2 of complement factor H | 分子名称: | Complement factor H | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | 登録日 | 2007-07-28 | 公開日 | 2008-02-19 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2UWN
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | 登録日 | 2007-03-22 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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3RJ3
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3SW0
| Structure of the C-terminal region (modules 18-20) of complement regulator Factor H | 分子名称: | Complement factor H, GLYCEROL, PHOSPHATE ION | 著者 | Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P. | 登録日 | 2011-07-13 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH). Plos One, 7, 2012
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4ONT
| Ternary host recognition complex of complement factor H, C3d, and sialic acid | 分子名称: | Complement C3d fragment, Complement factor H, GLYCEROL, ... | 著者 | Blaum, B.S, Stehle, T.S. | 登録日 | 2014-01-29 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for sialic acid-mediated self-recognition by complement factor H. Nat.Chem.Biol., 11, 2015
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2WCY
| NMR solution structure of factor I-like modules of complement C7. | 分子名称: | COMPLEMENT COMPONENT C7 | 著者 | Phelan, M.M, Thai, C.T, Soares, D.C, Ogata, R.T, Barlow, P.N, Bramham, J. | 登録日 | 2009-03-17 | 公開日 | 2009-05-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement. J.Biol.Chem., 284, 2009
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