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4XQF
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BU of 4xqf by Molmil
Tailspike protein mutant E372Q (delta D470/N471) of E. coli bacteriophage HK620
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S.
Deposit date:2015-01-19
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
3FIL
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BU of 3fil by Molmil
Structural and energetic determinants for hyperstable variants of GB1 obtained from in-vitro evolution
Descriptor: CALCIUM ION, Immunoglobulin G-binding protein G
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2008-12-12
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:Dimer Formation of a Stabilized Gbeta1 Variant: A Structural and Energetic Analysis
J.Mol.Biol., 391, 2009
4URR
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BU of 4urr by Molmil
Tailspike protein of Sf6 bacteriophage bound to Shigella flexneri O- antigen octasaccharide fragment
Descriptor: 1,2-ETHANEDIOL, BIFUNCTIONAL TAIL PROTEIN, MANGANESE (II) ION, ...
Authors:Gohlke, U, Heinemann, U, Seckler, R, Barbirz, S.
Deposit date:2014-07-01
Release date:2015-07-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein-Polysaccharide Interactions.
J.Am.Chem.Soc., 138, 2016
1NEG
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BU of 1neg by Molmil
Crystal Structure Analysis of N-and C-terminal labeled SH3-domain of alpha-Chicken Spectrin
Descriptor: AZIDE ION, Spectrin alpha chain, brain
Authors:Mueller, U, Buessow, K, Diehl, A, Niesen, F.H, Nyarsik, L, Heinemann, U.
Deposit date:2002-12-11
Release date:2003-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags
J.STRUCT.FUNCT.GENOM., 4, 2003
1ONI
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BU of 1oni by Molmil
Crystal structure of a human p14.5, a translational inhibitor reveals different mode of ligand binding near the invariant residues of the Yjgf/UK114 protein family
Descriptor: 14.5 kDa translational inhibitor protein, BENZOIC ACID
Authors:Manjasetty, B.A, Delbrueck, H, Mueller, U, Erdmann, M.F, Heinemann, U.
Deposit date:2003-02-28
Release date:2003-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Homo sapiens protein hp14.5.
Proteins, 54, 2004
5IFW
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BU of 5ifw by Molmil
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Tether containing UBX domain for GLUT4, Transitional endoplasmic reticulum ATPase
Authors:Roske, Y, Heinemann, U.
Deposit date:2016-02-26
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun, 7, 2016
2JJZ
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BU of 2jjz by Molmil
Crystal Structure of Human Iba2, orthorhombic crystal form
Descriptor: ACETATE ION, CHLORIDE ION, IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2, ...
Authors:Schulze, J.O, Quedenau, C, Roske, Y, Turnbull, A, Mueller, U, Heinemann, U, Buessow, K.
Deposit date:2008-05-15
Release date:2009-07-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Characterization of Human Iba Proteins.
FEBS J., 275, 2008
5IFS
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BU of 5ifs by Molmil
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Roske, Y, Arumughan, A, Heinemann, U, Wanker, E.
Deposit date:2016-02-26
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun, 7, 2016
7NDH
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BU of 7ndh by Molmil
Crystal structure of ZC3H12C PIN domain
Descriptor: 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, SODIUM ION
Authors:Garg, A, Heinemann, U.
Deposit date:2021-02-01
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
7NDJ
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BU of 7ndj by Molmil
Crystal structure of ZC3H12C PIN-CCCH Zn Finger domain with RNA heptamer
Descriptor: 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, RNA (5'-R(*UP*UP*AP*UP*UP*AP*U)-3'), ...
Authors:Garg, A, Heinemann, U.
Deposit date:2021-02-01
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
7NDI
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BU of 7ndi by Molmil
Crystal structure of ZC3H12C PIN domain with Mg2+ Ion
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Probable ribonuclease ZC3H12C, ...
Authors:Garg, A, Heinemann, U.
Deposit date:2021-02-01
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.875 Å)
Cite:PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
7NDK
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BU of 7ndk by Molmil
Crystal structure of ZC3H12C PIN catalytic mutant
Descriptor: Probable ribonuclease ZC3H12C, SODIUM ION
Authors:Garg, A, Heinemann, U.
Deposit date:2021-02-01
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
2OKN
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BU of 2okn by Molmil
Crystal Strcture of Human Prolidase
Descriptor: HYDROGENPHOSPHATE ION, MANGANESE (II) ION, Xaa-Pro dipeptidase
Authors:Mueller, U, Niesen, F.H, Roske, Y, Goetz, F, Behlke, J, Buessow, K, Heinemann, U, Protein Structure Factory (PSF)
Deposit date:2007-01-17
Release date:2007-02-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of Human Prolidase: The Molecular Basis of PD Disease.
To be Published
4ZP3
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BU of 4zp3 by Molmil
AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA
Descriptor: A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Goetz, F, Roske, Y, Faelber, K, Zuehlke, K, Autenrieth, K, Kreuchwig, A, Krause, G, Herberg, F.W, Daumke, O, Heinemann, U, Klussmann, E.
Deposit date:2015-05-07
Release date:2016-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Biochem.J., 473, 2016
1XCR
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BU of 1xcr by Molmil
Crystal Structure of Longer Splice Variant of PTD012 from Homo sapiens reveals a novel Zinc-containing fold
Descriptor: ACETIC ACID, ZINC ION, hypothetical protein PTD012
Authors:Manjasetty, B.A, Fieber-Erdmann, M, Roske, Y, Goetz, F, Buessow, K, Heinemann, U.
Deposit date:2004-09-03
Release date:2005-09-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold
Protein Sci., 15, 2006
5MR7
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BU of 5mr7 by Molmil
Crystal structure of the DBD domain of human Grhl2
Descriptor: Grainyhead-like protein 2 homolog
Authors:Schuetz, A, Ming, Q, Roske, Y, Heinemann, U.
Deposit date:2016-12-21
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
5MPH
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BU of 5mph by Molmil
Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
Descriptor: Grainyhead-like protein 1 homolog, IODIDE ION
Authors:Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
Deposit date:2016-12-16
Release date:2018-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.337 Å)
Cite:Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
5MPF
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BU of 5mpf by Molmil
Structural Basis of Gene Regulation by the Grainyhead Transcription Factor Superfamily
Descriptor: DNA (5'-D(*AP*AP*AP*AP*CP*CP*GP*GP*TP*TP*TP*T)-3'), Grainyhead-like protein 1 homolog
Authors:Ming, Q, Roske, Y, Schuetz, A, Walentin, K, Ibraimi, I, Schmidt-Ott, K.M, Heinemann, U.
Deposit date:2016-12-16
Release date:2018-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.918 Å)
Cite:Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Nucleic Acids Res., 46, 2018
1AQ0
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BU of 1aq0 by Molmil
BARLEY 1,3-1,4-BETA-GLUCANASE IN MONOCLINIC SPACE GROUP
Descriptor: 1,3-1,4-BETA-GLUCANASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION
Authors:Mueller, J.J, Thomsen, K.K, Heinemann, U.
Deposit date:1997-08-05
Release date:1998-02-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of barley 1,3-1,4-beta-glucanase at 2.0-A resolution and comparison with Bacillus 1,3-1,4-beta-glucanase.
J.Biol.Chem., 273, 1998
1B67
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BU of 1b67 by Molmil
CRYSTAL STRUCTURE OF THE HISTONE HMFA FROM METHANOTHERMUS FERVIDUS
Descriptor: PROTEIN (HISTONE HMFA), SULFATE ION
Authors:Decanniere, K, Sandman, K, Reeve, J.N, Heinemann, U.
Deposit date:1999-01-19
Release date:2000-01-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structures of recombinant histones HMfA and HMfB from the hyperthermophilic archaeon Methanothermus fervidus.
J.Mol.Biol., 303, 2000
1B6W
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BU of 1b6w by Molmil
CRYSTAL STRUCTURE OF THE SELENOMETHIONINE VARIANT OF HISTONE HMFB FROM METHANOTHERMUS FERVIDUS
Descriptor: PROTEIN (HISTONE HMFB)
Authors:Decanniere, K, Sandman, K, Reeve, J.N, Heinemann, U.
Deposit date:1999-01-19
Release date:2000-01-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of recombinant histones HMfA and HMfB from the hyperthermophilic archaeon Methanothermus fervidus.
J.Mol.Biol., 303, 2000
3PR6
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BU of 3pr6 by Molmil
Crystal structure analysis of yeast TRAPP associate protein Tca17
Descriptor: CHLORIDE ION, GLYCEROL, TRAPP-associated protein TCA17
Authors:Wang, C, Gohlke, U, Heinemann, U.
Deposit date:2010-11-29
Release date:2011-11-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the yeast TRAPP-associated protein Tca17.
Febs J., 281, 2014
1E6E
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BU of 1e6e by Molmil
ADRENODOXIN REDUCTASE/ADRENODOXIN COMPLEX OF MITOCHONDRIAL P450 SYSTEMS
Descriptor: ADRENODOXIN, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mueller, J.J, Lapko, A, Bourenkov, G, Ruckpaul, K, Heinemann, U.
Deposit date:2000-08-15
Release date:2001-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Adrenodoxin Reductase-Adrenodoxin Complex Structure Suggests Electron Transfer Path in Steroid Biosynthesis.
J.Biol.Chem., 276, 2001
1A7W
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BU of 1a7w by Molmil
CRYSTAL STRUCTURE OF THE HISTONE HMFB FROM METHANOTHERMUS FERVIDUS
Descriptor: CHLORIDE ION, HISTONE HMFB, ZINC ION
Authors:Decanniere, K, Sandman, K, Reeve, J.N, Heinemann, U.
Deposit date:1998-03-18
Release date:1999-03-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of recombinant histones HMfA and HMfB from the hyperthermophilic archaeon Methanothermus fervidus.
J.Mol.Biol., 303, 2000
2ONQ
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BU of 2onq by Molmil
Gbeta1 stabilization by in vitro evolution and computational design
Descriptor: Immunoglobulin G-binding protein G
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2007-01-24
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
J.Mol.Biol., 373, 2007

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