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2BTI
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BU of 2bti by Molmil
Structure-function studies of the RmsA CsrA post-transcriptional global regulator protein family reveals a class of RNA-binding structure
分子名称: ACETATE ION, CARBON STORAGE REGULATOR HOMOLOG, SULFATE ION
著者Heeb, S, Kuehne, S.A, Bycroft, M, Crivii, S, Allen, M.D, Haas, D, Camara, M, Williams, P.
登録日2005-05-31
公開日2006-01-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional Analysis of the Post-Transcriptional Regulator Rsma Reveals a Novel RNA-Binding Site.
J.Mol.Biol., 355, 2006
6TPR
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BU of 6tpr by Molmil
PqsR (MvfR) bound to inhibitory compound 40
分子名称: 2-[(5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-~{N}-(4-pyridin-2-yloxyphenyl)ethanamide, Transcriptional regulator MvfR
著者Richardson, W.K, Emsley, J.
登録日2019-12-14
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm GrownPseudomonas aeruginosa.
Front Chem, 8, 2020
8Q5K
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BU of 8q5k by Molmil
PqsR coinducer binding domain of Pseudomonas aeruginosa with ligand 2t : 2-(4-(3-((6-chloro-1-(2-methoxyethyl)-1H-benzo[d]imidazol-2-yl)amino)-2-hydroxypropoxy)phenyl)acetonitrile
分子名称: 1,2-ETHANEDIOL, 2-[4-[(2~{S})-3-[[6-chloranyl-1-(2-methoxyethyl)benzimidazol-2-yl]amino]-2-oxidanyl-propoxy]phenyl]ethanenitrile, Multiple virulence factor regulator MvfR
著者Markham-Lee, Z.J, Emsley, J.
登録日2023-08-09
公開日2024-01-17
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Design, Synthesis, and Evaluation of New 1 H -Benzo[ d ]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections.
J.Med.Chem., 67, 2024
8Q5L
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BU of 8q5l by Molmil
PqsR coinducer binding domain of Pseudomonas aeruginosa with ligand 2f: 2-(4-(3-((6-chloro-1-isopropyl-1H-benzo[d]imidazol-2-yl)amino)-2-hydroxypropoxy)phenyl)acetonitrile
分子名称: 2-[4-[(2~{S})-3-[(6-chloranyl-1-propan-2-yl-benzimidazol-2-yl)amino]-2-oxidanyl-propoxy]phenyl]ethanenitrile, Transcriptional regulator MvfR
著者Markham-Lee, Z.J, Emsley, J.
登録日2023-08-09
公開日2024-01-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design, Synthesis, and Evaluation of New 1 H -Benzo[ d ]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections.
J.Med.Chem., 67, 2024
4JVD
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BU of 4jvd by Molmil
Crystal structure of PqsR coinducer binding domain of Pseudomonas aeruginosa with ligand NHQ
分子名称: 2-nonylquinolin-4(1H)-one, Transcriptional regulator MvfR
著者Ilangovan, A, Emsley, J, Williams, P.
登録日2013-03-25
公開日2013-08-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR).
Plos Pathog., 9, 2013
4JVI
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BU of 4jvi by Molmil
Crystal structure of PqsR co-inducer binding domain of Pseudomonas aeruginosa with inhibitor 3NH2-7Cl-C9QZN
分子名称: 3-amino-7-chloro-2-nonylquinazolin-4(3H)-one, Transcriptional regulator MvfR
著者Ilangovan, A, Williams, P, Emsley, J.
登録日2013-03-25
公開日2013-08-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR).
Plos Pathog., 9, 2013
4JVC
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BU of 4jvc by Molmil
Crystal structure of PqsR co-inducer binding domain
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Transcriptional regulator MvfR
著者Ilangovan, A, Emsley, J, Williams, P.
登録日2013-03-25
公開日2013-08-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR).
Plos Pathog., 9, 2013
4KJI
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BU of 4kji by Molmil
Novel re-arrangement of an RsmA/cSRa family protein to create a structurally distinct new RNA-binding family member
分子名称: RsmN, a RNA-binding protein of Regulator of Secondary Metabolism, RsmZ-2
著者Li, C.
登録日2013-05-03
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN.
Structure, 21, 2013
4KRW
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BU of 4krw by Molmil
Novel re-arrangement of an RsmA/cSRa family protein to create a structurally distinct new RNA-binding family member
分子名称: IODIDE ION, RsmN, a RNA-binding protein of Regulator of Secondary Metabolism
著者Li, C.
登録日2013-05-17
公開日2013-09-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN.
Structure, 21, 2013

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件を2024-05-01に公開中

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