4JVI
Crystal structure of PqsR co-inducer binding domain of Pseudomonas aeruginosa with inhibitor 3NH2-7Cl-C9QZN
Summary for 4JVI
Entry DOI | 10.2210/pdb4jvi/pdb |
Related | 4JVC 4JVD |
Descriptor | Transcriptional regulator MvfR, 3-amino-7-chloro-2-nonylquinazolin-4(3H)-one (3 entities in total) |
Functional Keywords | co-inducer binding, dna, cytoplasmic, transcription regulator-inhibitor complex, transcription regulator/inhibitor |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 24610.32 |
Authors | Ilangovan, A.,Williams, P.,Emsley, J. (deposition date: 2013-03-25, release date: 2013-08-07, Last modification date: 2024-03-20) |
Primary citation | Ilangovan, A.,Fletcher, M.,Rampioni, G.,Pustelny, C.,Rumbaugh, K.,Heeb, S.,Camara, M.,Truman, A.,Chhabra, S.R.,Emsley, J.,Williams, P. Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). Plos Pathog., 9:e1003508-e1003508, 2013 Cited by PubMed: 23935486DOI: 10.1371/journal.ppat.1003508 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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