3D4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d4w by Molmil](/molmil-images/mine/3d4w) | Crystal structure of Staphylococcal nuclease variant Delta+PHS A109R at cryogenic temperature | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease | Authors: | Harms, M.J, Schlessman, J.L, Garcia-Moreno, E.B. | Deposit date: | 2008-05-15 | Release date: | 2009-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Arginine residues at internal positions in a protein are always charged. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3D6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d6c by Molmil](/molmil-images/mine/3d6c) | Crystal structure of Staphylococcal nuclease variant PHS L38E at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Harms, M.J, Schlessman, J.L, Sue, G.R, Garcia-Moreno, E.B. | Deposit date: | 2008-05-19 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors. J.Mol.Biol., 389, 2009
|
|
3D8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d8g by Molmil](/molmil-images/mine/3d8g) | Crystal structure of Staphylococcal nuclease variant Delta+PHS I72R at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Harms, M.J, Schlessman, J.L, Garcia-Moreno, E.B. | Deposit date: | 2008-05-23 | Release date: | 2009-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Arginine residues at internal positions in a protein are always charged. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3DHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dhq by Molmil](/molmil-images/mine/3dhq) | Crystal structure of Staphylococcal nuclease variant Delta+PHS A90R at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Harms, M.J, Schlessman, J.L, Garcia-Moreno, E.B. | Deposit date: | 2008-06-18 | Release date: | 2009-01-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Arginine residues at internal positions in a protein are always charged. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2RKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rks by Molmil](/molmil-images/mine/2rks) | |
6WN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wn7 by Molmil](/molmil-images/mine/6wn7) | Homo sapiens S100A5 | Descriptor: | CALCIUM ION, Protein S100-A5 | Authors: | Perkins, A, Harms, M.J, Wong, C.E, Wheeler, L.C. | Deposit date: | 2020-04-22 | Release date: | 2020-09-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Learning peptide recognition rules for a low-specificity protein. Protein Sci., 29, 2020
|
|
7UI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ui5 by Molmil](/molmil-images/mine/7ui5) | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9 | Descriptor: | CALCIUM ION, Protein S100-A9 | Authors: | Reardon, P.N, Harman, J.L, Costello, S.M, Warren, G.D, Phillips, S.R, Connor, P.J, Marqusee, S, Harms, M.J. | Deposit date: | 2022-03-28 | Release date: | 2022-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
4LY7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ly7 by Molmil](/molmil-images/mine/4ly7) | Ancestral RNase H | Descriptor: | Ribonuclease H, SULFATE ION | Authors: | Hart, K.M, Harms, M.J, Schmidt, B.H, Elya, C, Thornton, J.W, Marqusee, S. | Deposit date: | 2013-07-30 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Thermodynamic system drift in protein evolution. Plos Biol., 12, 2014
|
|
3HZX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hzx by Molmil](/molmil-images/mine/3hzx) | |
8VL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vl8 by Molmil](/molmil-images/mine/8vl8) | |
4FNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fne by Molmil](/molmil-images/mine/4fne) | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - DOC complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, DESOXYCORTICOSTERONE, ... | Authors: | Ortlund, E.A, Colucci, J.K, Thornton, J, Eick, G, Harms, M. | Deposit date: | 2012-06-19 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Evolution of minimal specificity and promiscuity in steroid hormone receptors. PLoS Genet, 8, 2012
|
|
8FYV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fyv by Molmil](/molmil-images/mine/8fyv) | Salmonella enterica serovar Typhimurium chemoreceptor Tsr (taxis to serine and repellents) ligand-binding domain in complex with l-serine | Descriptor: | CHLORIDE ION, Methyl-accepting chemotaxis protein, SERINE, ... | Authors: | Baylink, A, Gentry-Lear, Z, Glenn, S. | Deposit date: | 2023-01-26 | Release date: | 2024-05-15 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bacterial vampirism mediated through taxis to serum. Elife, 12, 2024
|
|
8G9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g9a by Molmil](/molmil-images/mine/8g9a) | Crystal structure of a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, SULFATE ION, ... | Authors: | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2023-02-21 | Release date: | 2024-02-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. J.Biol.Chem., 300, 2024
|
|
6XHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xhz by Molmil](/molmil-images/mine/6xhz) | Alpha-lytic protease homolog N4 | Descriptor: | N4: hypothetical protein, SULFATE ION | Authors: | Nixon, C.F, Marqusee, S.M, Gee, C.L. | Deposit date: | 2020-06-19 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Exploring the Evolutionary History of Kinetic Stability in the alpha-Lytic Protease Family. Biochemistry, 60, 2021
|
|
4FN9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fn9 by Molmil](/molmil-images/mine/4fn9) | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - Progesterone complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, ... | Authors: | Colucci, J.K, Ortlund, E.A, Thornton, J.W. | Deposit date: | 2012-06-19 | Release date: | 2012-12-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Evolution of minimal specificity and promiscuity in steroid hormone receptors. PLoS Genet., 8, 2012
|
|
7TY1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ty1 by Molmil](/molmil-images/mine/7ty1) | Crystal structure of apo eosinophil cationic protein (ribonuclease 3) from Macaca fascicularis (MfECP) | Descriptor: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, Eosinophil cationic protein, ... | Authors: | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2022-02-11 | Release date: | 2023-08-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. J.Biol.Chem., 300, 2024
|
|
8F5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f5x by Molmil](/molmil-images/mine/8f5x) | Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP) | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Non-secretory ribonuclease, ... | Authors: | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2022-11-15 | Release date: | 2023-11-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. J.Biol.Chem., 300, 2024
|
|