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Transmembrane AMPA Receptor Regulatory Protein Subunit Gamma 2
Descriptor:	Voltage-dependent calcium channel gamma-2 subunit
Authors:	Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C.
Deposit date:	2024-01-02
Release date:	2025-01-22
Last modified:	2025-01-29
Method:	ELECTRON MICROSCOPY (2.3 Å)
Cite:	Structure of transmembrane AMPA receptor regulatory protein subunit gamma 2. Nat Commun, 16, 2025

GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 1
Descriptor:	4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, Isoform Flip of Glutamate receptor 2
Authors:	Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C.
Deposit date:	2024-01-05
Release date:	2024-06-05
Last modified:	2024-11-27
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	Allosteric competition and inhibition in AMPA receptors. Nat.Struct.Mol.Biol., 31, 2024

GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2
Descriptor:	4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2
Authors:	Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C.
Deposit date:	2024-01-05
Release date:	2024-06-05
Last modified:	2024-11-27
Method:	ELECTRON MICROSCOPY (4.85 Å)
Cite:	Allosteric competition and inhibition in AMPA receptors. Nat.Struct.Mol.Biol., 31, 2024