8J01
 
 | | Human KCNQ2-CaM in complex with CBD and PIP2 | | Descriptor: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | | Authors: | Ma, D, Li, X, Guo, J. | | Deposit date: | 2023-04-09 | | Release date: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
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8IKJ
 | | Cryo-EM structure of the inactive CD97 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta | | Authors: | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y. | | Deposit date: | 2023-02-28 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
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5CB0
 | | Crystal structure and functional implications of the tandem-type universal stress protein UspE from Escherichia coli | | Descriptor: | 3-oxotetradecanoic acid, Universal stress protein E | | Authors: | Xu, Y, Quan, C.S, Jin, X, Jin, L, Kim, J.S, Guo, J, Fan, S, Ha, N.C. | | Deposit date: | 2015-06-30 | | Release date: | 2016-02-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.207 Å) | | Cite: | Crystal structure and functional implications of the tandem-type universal stress protein UspE from Escherichia coli.
Bmc Struct.Biol., 16, 2016
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5F6T
 | | Structure of calexcitin-Gd3+ complex. | | Descriptor: | CALCIUM ION, Calexcitin, GADOLINIUM ATOM | | Authors: | Chataigner, L, Guo, J, Erskine, P.T, Coker, A.R, Wood, S.P, Cooper, J.B. | | Deposit date: | 2015-12-06 | | Release date: | 2015-12-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Binding of Gd(3+) to the neuronal signalling protein calexcitin identifies an exchangeable Ca(2+)-binding site.
Acta Crystallogr.,Sect.F, 72, 2016
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3P2M
 | | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis | | Descriptor: | POSSIBLE HYDROLASE | | Authors: | Zheng, X.D, Guo, J, Xu, L, Li, H, Zhang, D, Zhang, K, Sun, F, Wen, T, Liu, S, Pang, H. | | Deposit date: | 2010-10-03 | | Release date: | 2011-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
Plos One, 6, 2011
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5GOV
 | | Crystal Structure of MCR-1, a phosphoethanolamine transferase, extracellular domain | | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | Authors: | Hu, M, Guo, J, Chen, S, Hao, Q. | | Deposit date: | 2016-07-29 | | Release date: | 2016-12-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance.
Sci Rep, 6, 2016
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7F6G
 | | Cryo-EM structure of human angiotensin receptor AT1R in complex Gq proteins and Sar1-AngII | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin receptor AT1R, CHOLESTEROL, ... | | Authors: | Zhang, D, Xu, L, Zhan, Y, Guo, J, Zhang, H. | | Deposit date: | 2021-06-25 | | Release date: | 2023-03-29 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into angiotensin receptor signaling modulation by balanced and biased agonists.
Embo J., 42, 2023
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5JK4
 | | Phosphate-Binding Protein from Stenotrophomonas maltophilia. | | Descriptor: | Alkaline phosphatase, PHOSPHATE ION | | Authors: | Keegan, R, Waterman, D, Hopper, D, Coates, L, Guo, J, Coker, A.R, Erskine, P.T, Wood, S.P, Cooper, J.B. | | Deposit date: | 2016-04-25 | | Release date: | 2016-05-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | The 1.1 angstrom resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.
Acta Crystallogr D Struct Biol, 72, 2016
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3DX2
 | | Golgi mannosidase II complex with MANNOSTATIN B | | Descriptor: | (1R,2R,3R,4S,5R)-4-amino-5-[(R)-methylsulfinyl]cyclopentane-1,2,3-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | Authors: | Kuntz, D.A, Zhong, W, Guo, J, Rose, D.R, Boons, G.-J. | | Deposit date: | 2008-07-23 | | Release date: | 2009-07-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A.
Chembiochem, 10, 2009
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8I5M
 | | Rat Kir4.1 in complex with PIP2 | | Descriptor: | ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Zhao, C, Guo, J. | | Deposit date: | 2023-01-26 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses
To Be Published
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8I5N
 | | Rat Kir4.1 in complex with PIP2 and Lys05 | | Descriptor: | ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Zhao, C, Guo, J. | | Deposit date: | 2023-01-26 | | Release date: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses
To Be Published
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8IOY
 | | Structure of ATP7B C983S/C985S/D1027A mutant with AMP-PNP | | Descriptor: | Copper-transporting ATPase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Yang, G, Xu, L, Guo, J, Wu, Z. | | Deposit date: | 2023-03-13 | | Release date: | 2023-04-26 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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8IRL
 | | Apo state of Arabidopsis AZG1 at pH 7.4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | | Authors: | Xu, L, Guo, J. | | Deposit date: | 2023-03-19 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRN
 | | 6-BAP bound state of Arabidopsis AZG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-BENZYL-9H-PURIN-6-AMINE | | Authors: | Xu, L, Guo, J. | | Deposit date: | 2023-03-19 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRP
 | | kinetin bound state of Arabidopsis AZG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE | | Authors: | Xu, L, Guo, J. | | Deposit date: | 2023-03-19 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRM
 | | Endogenous substrate adenine bound state of Arabidopsis AZG1 at pH 5.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Adenine/guanine permease AZG1 | | Authors: | Xu, L, Guo, J. | | Deposit date: | 2023-03-19 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRO
 | | trans-Zeatin bound state of Arabidopsis AZG1 at pH7.4 | | Descriptor: | (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | | Authors: | Xu, L, Guo, J. | | Deposit date: | 2023-03-19 | | Release date: | 2024-01-17 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8JMA
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8JMH
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8JMI
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8JME
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8JM9
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4NVQ
 | | Human G9a in Complex with Inhibitor A-366 | | Descriptor: | 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Sweis, R.F, Pliushchev, M, Brown, P.J, Guo, J, Li, F, Maag, D, Petros, A.M, Soni, N.B, Tse, C, Vedadi, M, Michaelides, M.R, Chiang, G.G, Pappano, W.N. | | Deposit date: | 2013-12-05 | | Release date: | 2014-01-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
ACS Med Chem Lett, 5, 2014
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3KH8
 | | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | | Descriptor: | MaoC-like dehydratase | | Authors: | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | | Deposit date: | 2009-10-30 | | Release date: | 2010-11-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici
To be Published
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4P9G
 | | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. | | Descriptor: | 2,4'-dihydroxyacetophenone dioxygenase, CARBONATE ION, FE (III) ION, ... | | Authors: | Keegan, R, Lebedev, A, Erskine, P, Guo, J, Wood, S.P, Hopper, D.J, Cooper, J.B. | | Deposit date: | 2014-04-03 | | Release date: | 2014-09-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP
Acta Crystallogr.,Sect.D, 70, 2014
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