6TBP
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6T71
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6TAW
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6T49
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6T2X
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6T3G
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6T4S
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6T5D
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6TAL
| 3C-like protease from Southampton virus complexed with FMOPL000227a. | Descriptor: | 5-ethyl-1,3,4-thiadiazol-2-amine, DIMETHYL SULFOXIDE, Genome polyprotein, ... | Authors: | Guo, J, Cooper, J.B. | Deposit date: | 2019-10-29 | Release date: | 2020-08-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors. J Struct Biol X, 4, 2020
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5BPX
| Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP. | Descriptor: | 2,4'-dihydroxyacetophenone dioxygenase, ACETATE ION, FE (III) ION, ... | Authors: | Guo, J, Erskine, P, Wood, S.P, Cooper, J.B. | Deposit date: | 2015-05-28 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Extension of resolution and oligomerization-state studies of 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP. Acta Crystallogr.,Sect.F, 71, 2015
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5TUA
| structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1 | Descriptor: | BARIUM ION, CALCIUM ION, SODIUM ION, ... | Authors: | Guo, J, Zeng, W, Jiang, Y. | Deposit date: | 2016-11-05 | Release date: | 2017-01-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Tuning the ion selectivity of two-pore channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5E1J
| Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | Descriptor: | BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1 | Authors: | Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y. | Deposit date: | 2015-09-29 | Release date: | 2015-12-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.308 Å) | Cite: | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana. Nature, 531, 2016
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5DZU
| Structure of potato cathepsin D inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease inhibitor 11, ... | Authors: | Guo, J, Erskine, P, Coker, A.R, Wood, S.P, Cooper, J.B. | Deposit date: | 2015-09-26 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structure of a Kunitz-type potato cathepsin D inhibitor. J.Struct.Biol., 192, 2015
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4LP9
| Endothiapepsin complexed with Phe-reduced-Tyr peptide. | Descriptor: | Endothiapepsin, GLYCEROL, SULFATE ION, ... | Authors: | Guo, J, Cooper, J.B, Wood, S.P. | Deposit date: | 2013-07-15 | Release date: | 2014-01-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The structure of endothiapepsin complexed with a Phe-Tyr reduced-bond inhibitor at 1.35 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 70, 2014
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4IX3
| Crystal structure of a Stt7 homolog from Micromonas algae | Descriptor: | MAGNESIUM ION, MsStt7d protein | Authors: | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | Deposit date: | 2013-01-24 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4J1L
| Mutant Endotoxin TeNT | Descriptor: | Tetanus toxin, ZINC ION | Authors: | Guo, J, Pan, X, Zhao, Y, Chen, S. | Deposit date: | 2013-02-01 | Release date: | 2014-02-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Engineering Clostridia Neurotoxins with elevated catalytic activity Toxicon, 74, 2013
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4IX5
| Crystal structure of a Stt7 homolog from Micromonas algae in complex with AMP-PNP | Descriptor: | MAGNESIUM ION, MsStt7d protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | Deposit date: | 2013-01-24 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4IX6
| Crystal structure of a Stt7 homolog from Micromonas algae soaked with ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MsStt7d protein | Authors: | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | Deposit date: | 2013-01-24 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4IX4
| Crystal structure of a Stt7 homolog from Micromonas algae in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MsStt7d protein | Authors: | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | Deposit date: | 2013-01-24 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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7CBG
| Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor | Descriptor: | (2S,3R)-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-2-(methylamino)-3-oxidanyl-butanamide, Threonine--tRNA ligase, ZINC ION | Authors: | Guo, J, Chen, B, Zhou, H. | Deposit date: | 2020-06-12 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors. Eur.J.Med.Chem., 207, 2020
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7CBI
| Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor | Descriptor: | 1,2-ETHANEDIOL, 5-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)pentyl (2~{S},3~{R})-2-azanyl-3-oxidanyl-butanoate, GLYCEROL, ... | Authors: | Guo, J, Chen, B, Zhou, H. | Deposit date: | 2020-06-12 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors. Eur.J.Med.Chem., 207, 2020
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7CBH
| Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor | Descriptor: | Threonine--tRNA ligase, ZINC ION, [(E)-4-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)but-2-enyl] (2S,3R)-2-azanyl-3-oxidanyl-butanoate | Authors: | Guo, J, Chen, B, Zhou, H. | Deposit date: | 2020-06-12 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors. Eur.J.Med.Chem., 207, 2020
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6BCL
| cryo-EM structure of TRPM4 in apo state with long coiled coil at 3.5 angstrom resolution | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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6BCJ
| cryo-EM structure of TRPM4 in apo state with short coiled coil at 3.1 angstrom resolution | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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6BCQ
| cryo-EM structure of TRPM4 in ATP bound state with long coiled coil at 3.3 angstrom resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily M member 4 | Authors: | Guo, J, She, J, Chen, Q, Bai, X, Jiang, Y. | Deposit date: | 2017-10-20 | Release date: | 2017-12-13 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structures of the calcium-activated, non-selective cation channel TRPM4. Nature, 552, 2017
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