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5DKP
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BU of 5dkp by Molmil
Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.
Descriptor: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION, SODIUM ION, ...
Authors:Goodreid, J.D, Janetzko, J, Santa Maria Jr, J.P, Wong, K, Leung, E, Eger, B.T, Bryson, S, Pai, E.F, Gray-Owen, S.D, Walker, S, Houry, W.A, Batey, R.A.
Deposit date:2015-09-03
Release date:2016-01-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity.
J.Med.Chem., 59, 2016
7K9Z
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BU of 7k9z by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 298 Fab Heavy Chain, 298 Fab Light Chain, ...
Authors:Newton, J.C, Kucharska, I, Rujas, E, Cui, H, Julien, J.P.
Deposit date:2020-09-29
Release date:2020-10-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Nat Commun, 12, 2021
4RDR
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BU of 4rdr by Molmil
Structure of the bacterial Zn-transporter ZnuD from Neisseria meningitidis (locked conformation bound to zinc and cadmium ions)
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, CADMIUM ION, ...
Authors:Calmettes, C, Moraes, T.F.
Deposit date:2014-09-19
Release date:2015-08-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.
Nat Commun, 6, 2015
4RDT
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BU of 4rdt by Molmil
Structure of the bacterial Zn-transporter ZnuD from Neisseria meningitidis (flexible conformation bound to a zinc ion)
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, GLYCEROL, SULFATE ION, ...
Authors:Calmettes, C, El Bakkouri, M, Moraes, T.F.
Deposit date:2014-09-19
Release date:2015-08-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.
Nat Commun, 6, 2015
4RVW
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BU of 4rvw by Molmil
Structure of the bacterial Zn-transporter ZnuD from Neisseria meningitidis (soaked with 20 micromolar Zinc)
Descriptor: SULFATE ION, ZINC ION, ZnuD
Authors:Calmettes, C, Moraes, T.F.
Deposit date:2014-11-28
Release date:2015-08-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.477 Å)
Cite:The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.
Nat Commun, 6, 2015
6W9T
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BU of 6w9t by Molmil
Crystal structure of Neisseria meningitidis ClpP protease complex with small molecule activator ACP1-06
Descriptor: ATP-dependent Clp protease proteolytic subunit, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide, POTASSIUM ION
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2020-03-23
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Development of Antibiotics That Dysregulate the Neisserial ClpP Protease.
Acs Infect Dis., 6, 2020
5TED
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BU of 5ted by Molmil
Effector binding domain of QuiR in complex with shikimate
Descriptor: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, His Tag peptide, Lmo0488 protein
Authors:Prezioso, S.M, Christendat, D.
Deposit date:2016-09-21
Release date:2017-10-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.889 Å)
Cite:Shikimate Induced Transcriptional Activation of Protocatechuate Biosynthesis Genes by QuiR, a LysR-Type Transcriptional Regulator, in Listeria monocytogenes.
J. Mol. Biol., 430, 2018
7RED
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BU of 7red by Molmil
Holo Hemophilin from A. baumannii
Descriptor: Hemophilin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bateman, T.J, Shah, M, Moraes, T.F.
Deposit date:2021-07-12
Release date:2021-11-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii.
Nat Commun, 12, 2021
7RE4
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BU of 7re4 by Molmil
Apo Hemophilin from A. baumannii
Descriptor: Hemophilin
Authors:Bateman, T.J, Shah, M, Moraes, T.F.
Deposit date:2021-07-12
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii.
Nat Commun, 12, 2021
7REA
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BU of 7rea by Molmil
Apo Hemophilin from A. baumannii
Descriptor: Hemophilin
Authors:Bateman, T.J, Shah, M, Moraes, T.F.
Deposit date:2021-07-12
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii.
Nat Commun, 12, 2021
8SZN
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BU of 8szn by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12
Descriptor: 2-{bis[5-(trifluoromethyl)pyridin-2-yl]phosphoryl}-2-methyl-N-(2-{[2-(trifluoromethyl)phenyl]sulfanyl}ethyl)propanamide, ATP-dependent Clp protease proteolytic subunit
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2023-05-30
Release date:2024-09-18
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
J.Med.Chem., 67, 2024
8SZM
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BU of 8szm by Molmil
Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12
Descriptor: 2-{bis[5-(trifluoromethyl)pyridin-2-yl]phosphoryl}-2-methyl-N-(2-{[2-(trifluoromethyl)phenyl]sulfanyl}ethyl)propanamide, ATP-dependent Clp protease proteolytic subunit
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2023-05-30
Release date:2024-09-18
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
J.Med.Chem., 67, 2024

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PDB entries from 2024-11-06

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