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6PLU
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BU of 6plu by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, desensitized state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ...
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-01-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM0
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BU of 6pm0 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, super-open state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLQ
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BU of 6plq by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM1
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BU of 6pm1 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM3
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BU of 6pm3 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, closed state
Descriptor: 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM4
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BU of 6pm4 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM5
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BU of 6pm5 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, desensitized state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM2
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BU of 6pm2 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state
Descriptor: 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PM6
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BU of 6pm6 by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state
Descriptor: GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLP
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BU of 6plp by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
6PLW
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BU of 6plw by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state
Descriptor: GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yu, J, Zhu, H, Gouaux, E.
Deposit date:2019-07-01
Release date:2021-02-10
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
4MM4
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BU of 4mm4 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with paroxetine
Descriptor: CHLORIDE ION, Paroxetine, SODIUM ION, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM8
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BU of 4mm8 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (R)-fluoxetine
Descriptor: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMF
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BU of 4mmf by Molmil
Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol
Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM9
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BU of 4mm9 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with fluvoxamine
Descriptor: Fluvoxamine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM5
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BU of 4mm5 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMB
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BU of 4mmb by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMD
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BU of 4mmd by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM7
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BU of 4mm7 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMC
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BU of 4mmc by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with desvenlafaxine
Descriptor: 4-[(1R)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MMA
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BU of 4mma by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with clomipramine
Descriptor: 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MM6
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BU of 4mm6 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4MME
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BU of 4mme by Molmil
Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol
Descriptor: (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ...
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4NTW
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BU of 4ntw by Molmil
Structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014
4NTY
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BU of 4nty by Molmil
Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ...
Authors:Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E.
Deposit date:2013-12-02
Release date:2014-02-19
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
Cell(Cambridge,Mass.), 156, 2014

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PDB entries from 2024-05-01

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