6HV8
 
 | | Cryo-EM structure of S. cerevisiae Polymerase epsilon deltacat mutant | | Descriptor: | DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit B, ZINC ION | | Authors: | Goswami, P, Purkiss, A, Cheung, A, Costa, A. | | Deposit date: | 2018-10-10 | | Release date: | 2018-12-12 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
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6SCX
 | | Crystal structure of the catalytic domain of human NUDT12 in complex with 7-methyl-guanosine-5'-triphosphate | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Peroxisomal NADH pyrophosphatase NUDT12 | | Authors: | McCarthy, A.A, Chen, K.M, Wu, H, Li, L, Homolka, D, Gos, P, Fleury-Olela, F, Pillai, R.S. | | Deposit date: | 2019-07-25 | | Release date: | 2020-01-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Cell Rep, 29, 2019
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6QM8
 | | Leishmania tarentolae proteasome 20S subunit apo structure | | Descriptor: | Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ... | | Authors: | Rowland, P, Goswami, P. | | Deposit date: | 2019-02-01 | | Release date: | 2019-04-17 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6QM7
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2IWV
 | | Structure of the monomeric outer membrane porin OmpG in the open and closed conformation | | Descriptor: | CALCIUM ION, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, ... | | Authors: | Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W. | | Deposit date: | 2006-07-04 | | Release date: | 2006-08-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation.
Embo J., 25, 2006
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2IWW
 | | Structure of the monomeric outer membrane porin OmpG in the open and closed conformation | | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, beta-D-glucopyranose, ... | | Authors: | Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W. | | Deposit date: | 2006-07-05 | | Release date: | 2006-08-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation.
Embo J., 25, 2006
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6HV9
 | | S. cerevisiae CMG-Pol epsilon-DNA | | Descriptor: | Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ... | | Authors: | Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A. | | Deposit date: | 2018-10-10 | | Release date: | 2018-12-12 | | Last modified: | 2023-07-05 | | Method: | ELECTRON MICROSCOPY (4.98 Å) | | Cite: | Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
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6GFN
 | | METTL16 MTase domain | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | | Authors: | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | | Deposit date: | 2018-05-01 | | Release date: | 2018-09-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mol. Cell, 71, 2018
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6GT5
 | | METTL16 MTase domain (crystal form 2) | | Descriptor: | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | | Authors: | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | | Deposit date: | 2018-06-15 | | Release date: | 2018-09-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mol. Cell, 71, 2018
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6GFK
 | | delta-N METTL16 MTase domain | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | | Authors: | Chen, K.M, Mendel, M, Homolka, D, McCarthy, A.A, Pillai, R.S. | | Deposit date: | 2018-04-30 | | Release date: | 2018-09-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development.
Mol. Cell, 71, 2018
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7NYQ
 | | Crystal structure of the Mei-P26 NHL domain | | Descriptor: | Meiotic P26, isoform C | | Authors: | Salerno-Kochan, A, Gaik, M, Medenbach, J, Glatt, S. | | Deposit date: | 2021-03-23 | | Release date: | 2022-05-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26.
Life Sci Alliance, 5, 2022
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1CYO
 | | BOVINE CYTOCHROME B(5) | | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Durley, R.C.E, Mathews, F.S. | | Deposit date: | 1994-08-03 | | Release date: | 1994-11-30 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Refinement and structural analysis of bovine cytochrome b5 at 1.5 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
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8OLU
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8RFB
 | | Cryo-EM structure of the R243C mutant of human Prolyl Endopeptidase-Like (PREPL) protein involved in Congenital myasthenic syndrome-22 (CMS22) | | Descriptor: | Prolyl endopeptidase-like | | Authors: | Theodoropoulou, A, Cavani, E, Antanasijevic, A, Marcaida, M.J, Dal Peraro, M. | | Deposit date: | 2023-12-12 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.01 Å) | | Cite: | Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.
JCI Insight, 9, 2024
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8Q8J
 | | Crystal structure of human GPX4-R152H | | Descriptor: | Glutathione peroxidase | | Authors: | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | | Deposit date: | 2023-08-18 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of human GPX4-R152H
To Be Published
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8Q8N
 | | Crystal structure of human GPX4-U46C-I129S-L130S | | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | | Authors: | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | | Deposit date: | 2023-08-18 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
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1GPD
 | | STUDIES OF ASYMMETRY IN THE THREE-DIMENSIONAL STRUCTURE OF LOBSTER D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | | Descriptor: | D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | | Authors: | Moras, D, Olsen, K.W, Sabesan, M.N, Buehner, M, Ford, G.C, Rossmann, M.G. | | Deposit date: | 1975-07-01 | | Release date: | 1977-02-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase.
J.Biol.Chem., 250, 1975
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4GPD
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1IEU
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1IET
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