6HV8

Cryo-EM structure of S. cerevisiae Polymerase epsilon deltacat mutant

Summary for 6HV8

• Entry DOI: 10.2210/pdb6hv8/pdb
• EMDB information: 0287
• Descriptor: DNA polymerase epsilon subunit B, DNA polymerase epsilon catalytic subunit A, ZINC ION (3 entities in total)
• Functional Keywords: polymerase epsilon, dna replication, enzyme, dna polymerase, dna binding protein
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 183524.42

Authors

Goswami, P.,Purkiss, A.,Cheung, A.,Costa, A. (deposition date: 2018-10-10, release date: 2018-12-12)

• Primary citation: Goswami, P.,Abid Ali, F.,Douglas, M.E.,Locke, J.,Purkiss, A.,Janska, A.,Eickhoff, P.,Early, A.,Nans, A.,Cheung, A.M.C.,Diffley, J.F.X.,Costa, A.; Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.; Nat Commun, 9:5061-5061, 2018; PubMed: 30498216; DOI: 10.1038/s41467-018-07417-1

Experimental method

ELECTRON MICROSCOPY (4.4 Å)