6HV8
Cryo-EM structure of S. cerevisiae Polymerase epsilon deltacat mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008622 | cellular_component | epsilon DNA polymerase complex |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003690 | molecular_function | double-stranded DNA binding |
| B | 0003697 | molecular_function | single-stranded DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006260 | biological_process | DNA replication |
| B | 0006261 | biological_process | DNA-templated DNA replication |
| B | 0008622 | cellular_component | epsilon DNA polymerase complex |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| B | 0042276 | biological_process | error-prone translesion synthesis |
| B | 0043596 | cellular_component | nuclear replication fork |
| B | 0045005 | biological_process | DNA-templated DNA replication maintenance of fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2301 |
| Chain | Residue |
| A | CYS2108 |
| A | CYS2111 |
| A | CYS2130 |
| A | CYS2133 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 2302 |
| Chain | Residue |
| A | CYS2164 |
| A | ARG2166 |
| A | CYS2167 |
| A | CYS2179 |
| A | CYS2181 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"14747467","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Motif: {"description":"CysB motif","evidences":[{"source":"UniProtKB","id":"P15436","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P15436","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
