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4IG4
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BU of 4ig4 by Molmil
Crystal structure of single mutant thermostable NPPase (N86S) from Geobacillus stearothermophilus
Descriptor: Thermostable NPPase
Authors:Guo, Z, Wang, F, Huang, J, Qiu, R, Yang, Z, Wang, Y, Gong, W, Ji, C.
Deposit date:2012-12-16
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal structure of thermostable NPPase from Geobacillus stearothermophilus
To be Published
4KN8
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BU of 4kn8 by Molmil
Crystal structure of Bs-TpNPPase
Descriptor: Thermostable NPPase
Authors:Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C.
Deposit date:2013-05-09
Release date:2014-04-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
7CMZ
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BU of 7cmz by Molmil
Crystal Structure of BRCT7/8 in Complex with the APS Motif of PHF8
Descriptor: DNA topoisomerase 2-binding protein 1, Histone lysine demethylase PHF8, POTASSIUM ION, ...
Authors:Che, S.Y, Ma, S, Cao, C, Yao, Z, Shi, L, Yang, N.
Deposit date:2020-07-29
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.695 Å)
Cite:PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability.
Sci Adv, 7, 2021
7CMW
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BU of 7cmw by Molmil
Complex structure of PARP1 catalytic domain with pamiparib
Descriptor: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1
Authors:Feng, Y.C, Peng, H, Hong, Y, Liu, Y.
Deposit date:2020-07-29
Release date:2020-12-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.
J.Med.Chem., 63, 2020

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