1M65
| YCDX PROTEIN | Descriptor: | Hypothetical protein ycdX, SODIUM ION, SULFATE ION, ... | Authors: | Teplyakov, A, Obmolova, G, Khil, P.P, Camerini-Otero, R.D, Gilliland, G.L, Structure 2 Function Project (S2F) | Deposit date: | 2002-07-12 | Release date: | 2003-04-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site PROTEINS: STRUCT.,FUNCT.,GENET., 51, 2003
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1GSQ
| THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS | Descriptor: | GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE | Authors: | Ji, X, Rosenvinge, E.C.V, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1995-01-09 | Release date: | 1995-06-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry, 34, 1995
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2GSQ
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1B4P
| CRYSTAL STRUCTURES OF CLASS MU CHIMERIC GST ISOENZYMES M1-2 AND M2-1 | Descriptor: | L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, PROTEIN (GLUTATHIONE S-TRANSFERASE), SULFATE ION | Authors: | Xiao, G, Chen, J, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1998-12-26 | Release date: | 2003-07-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structures of Class MU Chimeric GST Isoenzymes M1-2 and M2-1 To be Published
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1RUV
| RIBONUCLEASE A-URIDINE VANADATE COMPLEX: HIGH RESOLUTION RESOLUTION X-RAY STRUCTURE (1.3 A) | Descriptor: | RIBONUCLEASE A, TERTIARY-BUTYL ALCOHOL, URIDINE-2',3'-VANADATE | Authors: | Ladner, J.E, Wladkowski, B, Svensson, L.A, Sjolin, L, Gilliland, G.L. | Deposit date: | 1995-07-27 | Release date: | 1997-04-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | X-ray structure of a ribonuclease A-uridine vanadate complex at 1.3 A resolution. Acta Crystallogr.,Sect.D, 53, 1997
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4QHU
| Crystal Structure of IL-17A/Fab6785 complex | Descriptor: | CHLORIDE ION, Fab6785 heavy chain, Fab6785 light chain, ... | Authors: | Luo, J, Gilliland, G.L, Malia, T, Obmolova, G, Teplyakov, A. | Deposit date: | 2014-05-29 | Release date: | 2015-08-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | IL-17A Asymmetry in a Complex with a Neutralizing Antibody Fab6785 Reveals a Potential Mechanism of Receptor Differentiation To be Published
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2A45
| Crystal structure of the complex between thrombin and the central "E" region of fibrin | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Fibrinogen alpha chain, Fibrinogen beta chain, ... | Authors: | Pechik, I, Madrazo, J, Gilliland, G.L, Medved, L. | Deposit date: | 2005-06-27 | Release date: | 2006-05-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry, 45, 2006
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3ULU
| Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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3ULV
| Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.522 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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3ULS
| Crystal structure of Fab12 | Descriptor: | Fab12 heavy chain, Fab12 light chain | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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3QPX
| Crystal structure of Fab C2507 | Descriptor: | CADMIUM ION, CHLORIDE ION, Fab C2507 heavy chain, ... | Authors: | Luo, J, Teplyakov, A, Obmolova, O, Malia, T, Gilliland, G.L. | Deposit date: | 2011-02-14 | Release date: | 2011-08-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Fab C2507 To be Published
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5TLJ
| COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2016-10-11 | Release date: | 2017-02-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Mol. Immunol., 83, 2017
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5TL5
| COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2016-10-10 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of CD27 in complex with a neutralizing noncompeting antibody. Acta Crystallogr F Struct Biol Commun, 73, 2017
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3QPQ
| Crystal structure of ANTI-TLR3 antibody C1068 FAB | Descriptor: | C1068 heavy chain, C1068 light chain, GLYCEROL, ... | Authors: | Luo, J, Obmolova, G, Teplyakov, A, Gilliland, G.L. | Deposit date: | 2011-02-14 | Release date: | 2011-08-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Fab C1068 To be Published
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5TLK
| COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND H2191 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, H2191 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2016-10-11 | Release date: | 2017-02-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Mol. Immunol., 83, 2017
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5UBX
| Crystal structure of a mutant mIgG2b Fc heterodimer in complex with Protein A peptide analog Z34C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2B chain C region, ... | Authors: | Armstrong, A.A, Zwolak, A, Gilliland, G.L. | Deposit date: | 2016-12-21 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Modulation of protein A binding allows single-step purification of mouse bispecific antibodies that retain FcRn binding. MAbs, 9, 2017
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4EUG
| Crystallographic and Enzymatic Studies of an Active Site Variant H187Q of Escherichia Coli Uracil DNA Glycosylase: Crystal Structures of Mutant H187Q and its Uracil Complex | Descriptor: | PROTEIN (GLYCOSYLASE) | Authors: | Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. | Deposit date: | 1998-12-27 | Release date: | 1999-07-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187. Biochemistry, 38, 1999
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5EUG
| CRYSTALLOGRAPHIC AND ENZYMATIC STUDIES OF AN ACTIVE SITE VARIANT H187Q OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE: CRYSTAL STRUCTURES OF MUTANT H187Q AND ITS URACIL COMPLEX | Descriptor: | PROTEIN (GLYCOSYLASE), URACIL | Authors: | Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. | Deposit date: | 1998-12-27 | Release date: | 1999-07-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited. Proteins, 35, 1999
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2F6L
| X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis | Descriptor: | Chorismate mutase | Authors: | Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E. | Deposit date: | 2005-11-29 | Release date: | 2005-12-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. J.Bacteriol., 188, 2006
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3I84
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3IFD
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3I85
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5WK2
| CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, M116 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Gilliland, G.L. | Deposit date: | 2017-07-24 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural insights into chemokine CCL17 recognition by antibody M116. Biochem Biophys Rep, 13, 2018
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5WK3
| CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB | Descriptor: | C-C motif chemokine 17, GLYCEROL, M116 HEAVY CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Gilliland, G.L. | Deposit date: | 2017-07-24 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into chemokine CCL17 recognition by antibody M116. Biochem Biophys Rep, 13, 2018
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3I2C
| Crystal structure of anti-IL-23 antibody CNTO4088 | Descriptor: | CNTO4088 HEAVY CHAIN, CNTO4088 LIGHT CHAIN, GLYCEROL | Authors: | Teplyakov, A, Obmolova, G, Gilliland, G.L. | Deposit date: | 2009-06-29 | Release date: | 2009-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088. Acta Crystallogr.,Sect.F, 66, 2010
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