7RA9
 
 | | Designed StabIL-2 seq1 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Interleukin-2, PHOSPHATE ION | | 著者 | Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C. | | 登録日 | 2021-06-30 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7S2S
 | | nanobody bound to Interleukin-2Rbeta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ... | | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | | 登録日 | 2021-09-03 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
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7S2R
 | | nanobody bound to IL-2Rg | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | | 登録日 | 2021-09-03 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
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3PEE
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4OFD
 | | Crystal Structure of mouse Neph1 D1-D2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of IRRE-like protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OFI
 | | Crystal Structure of Duf (Kirre) D1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Kin of irre, isoform A, ... | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OQW
 | | Crystal structure of mCardinal far-red fluorescent protein | | 分子名称: | Fluorescent protein FP480 | | 著者 | Burg, J.S, Chu, J, Lam, A.J, Lin, M.Z, Garcia, K.C. | | 登録日 | 2014-02-10 | | 公開日 | 2014-03-12 | | 最終更新日 | 2014-05-14 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein.
Nat.Methods, 11, 2014
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4OF3
 | | Crystal Structure of SYG-1 D1-D2, Glycosylated | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Protein SYG-1, isoform b, ... | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OFP
 | | Crystal Structure of SYG-2 D3-D4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein SYG-2 | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-15 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OF8
 | | Crystal Structure of Rst D1-D2 | | 分子名称: | GLYCEROL, Irregular chiasm C-roughest protein, SODIUM ION | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OF7
 | | Crystal Structure of SYG-1 D1, Crystal Form 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein SYG-1, isoform b, ... | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OFY
 | | Crystal Structure of the Complex of SYG-1 D1-D2 and SYG-2 D1-D4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL MERCURY ION, ... | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-15 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OF6
 | | Crystal Structure of SYG-1 D1, Crystal form 1 | | 分子名称: | 1,2-ETHANEDIOL, Protein SYG-1, isoform b, ... | | 著者 | Ozkan, E, Garcia, K.C. | | 登録日 | 2014-01-14 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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4OF0
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4OFK
 | | Crystal Structure of SYG-2 D4 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Ozkan, E, Borek, D, Otwinowski, Z, Garcia, K.C. | | 登録日 | 2014-01-15 | | 公開日 | 2014-02-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis.
Cell(Cambridge,Mass.), 156, 2014
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3QIB
 | | Crystal structure of the 2B4 TCR in complex with MCC/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 beta chain, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | | 登録日 | 2011-01-26 | | 公開日 | 2011-04-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
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4P2Q
 | | Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c2 peptide, 5cc7 T-cell receptor alpha chain, ... | | 著者 | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | | 登録日 | 2014-03-04 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
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3QB7
 | | Interleukin-4 mutant RGA bound to cytokine receptor common gamma | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | | 著者 | Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C. | | 登録日 | 2011-01-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.245 Å) | | 主引用文献 | Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.
Nat.Chem.Biol., 8, 2012
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4P2R
 | | Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c1 peptide, 5cc7 T-cell receptor alpha chain, ... | | 著者 | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | | 登録日 | 2014-03-04 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.295 Å) | | 主引用文献 | Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
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4P2O
 | | Crystal structure of the 2B4 TCR in complex with 2A/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A peptide, 2B4 T-cell receptor alpha chain, ... | | 著者 | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | | 登録日 | 2014-03-04 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | | 主引用文献 | Deconstructing the Peptide-MHC Specificity of T Cell Recognition.
Cell, 157, 2014
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3QJH
 | | The crystal structure of the 5c.c7 TCR | | 分子名称: | 5c.c7 alpha chain, 5c.c7 beta chain | | 著者 | Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | | 登録日 | 2011-01-28 | | 公開日 | 2011-04-27 | | 最終更新日 | 2011-08-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
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3QJF
 | | Crystal structure of the 2B4 TCR | | 分子名称: | 2B4 alpha chain, 2B4 beta chain | | 著者 | Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | | 登録日 | 2011-01-28 | | 公開日 | 2011-04-27 | | 最終更新日 | 2011-08-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
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3QB1
 | | Interleukin-2 mutant D10 | | 分子名称: | Interleukin-2 | | 著者 | Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C. | | 登録日 | 2011-01-12 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
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3QIU
 | | Crystal structure of the 226 TCR in complex with MCC/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ... | | 著者 | Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | | 登録日 | 2011-01-27 | | 公開日 | 2011-04-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
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3QIW
 | | Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ... | | 著者 | Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | | 登録日 | 2011-01-27 | | 公開日 | 2011-04-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
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