4V95
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![BU of 4v95 by Molmil](/molmil-images/mine/4v95) | Crystal structure of YAEJ bound to the 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A. | Deposit date: | 2012-01-27 | Release date: | 2014-07-09 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science, 335, 2012
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5HCR
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![BU of 5hcr by Molmil](/molmil-images/mine/5hcr) | Crystal structure of antimicrobial peptide Oncocin 10wt bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2016-01-04 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5HCQ
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![BU of 5hcq by Molmil](/molmil-images/mine/5hcq) | Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2016-01-04 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5HAU
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![BU of 5hau by Molmil](/molmil-images/mine/5hau) | Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2015-12-30 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5HD1
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![BU of 5hd1 by Molmil](/molmil-images/mine/5hd1) | Crystal structure of antimicrobial peptide Pyrrhocoricin bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2016-01-04 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5J8B
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![BU of 5j8b by Molmil](/molmil-images/mine/5j8b) | Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Lin, J, Steitz, T.A. | Deposit date: | 2016-04-07 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Elongation factor 4 remodels the A-site tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5HCP
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![BU of 5hcp by Molmil](/molmil-images/mine/5hcp) | Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2016-01-04 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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4W2E
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![BU of 4w2e by Molmil](/molmil-images/mine/4w2e) | Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Lin, J, Steitz, T.A. | Deposit date: | 2014-06-04 | Release date: | 2014-10-01 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome. Science, 345, 2014
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4Z8C
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![BU of 4z8c by Molmil](/molmil-images/mine/4z8c) | Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Roy, R.N, Lomakin, I.B, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2015-04-08 | Release date: | 2015-05-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat.Struct.Mol.Biol., 22, 2015
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8G7S
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![BU of 8g7s by Molmil](/molmil-images/mine/8g7s) | |
8G7Q
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![BU of 8g7q by Molmil](/molmil-images/mine/8g7q) | |
8G7R
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![BU of 8g7r by Molmil](/molmil-images/mine/8g7r) | |
8G7P
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![BU of 8g7p by Molmil](/molmil-images/mine/8g7p) | |
4WQF
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![BU of 4wqf by Molmil](/molmil-images/mine/4wqf) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G and fusidic acid in the post-translocational state | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Lin, J, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2014-10-21 | Release date: | 2015-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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4WPO
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![BU of 4wpo by Molmil](/molmil-images/mine/4wpo) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Lin, J, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2014-10-20 | Release date: | 2015-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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4WQU
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![BU of 4wqu by Molmil](/molmil-images/mine/4wqu) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G trapped by the antibiotic dityromycin | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Lin, J, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2014-10-22 | Release date: | 2015-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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4WQY
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![BU of 4wqy by Molmil](/molmil-images/mine/4wqy) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Lin, J, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2014-10-22 | Release date: | 2015-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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8RDV
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![BU of 8rdv by Molmil](/molmil-images/mine/8rdv) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RDW
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![BU of 8rdw by Molmil](/molmil-images/mine/8rdw) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RD8
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![BU of 8rd8 by Molmil](/molmil-images/mine/8rd8) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-07 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8EKC
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![BU of 8ekc by Molmil](/molmil-images/mine/8ekc) | |
8EV6
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![BU of 8ev6 by Molmil](/molmil-images/mine/8ev6) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2022-10-19 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.946 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EV7
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![BU of 8ev7 by Molmil](/molmil-images/mine/8ev7) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2022-10-19 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8FZD
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![BU of 8fzd by Molmil](/molmil-images/mine/8fzd) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZE
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![BU of 8fze by Molmil](/molmil-images/mine/8fze) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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