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1BAK
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BU of 1bak by Molmil
SIGNAL TRANSDUCTION PLECKSTRIN HOMOLOGY DOMAIN OF G-PROTEIN COUPLED RECEPTOR KINASE 2 (BETA-ADRENERGIC RECEPTOR KINASE 1), C-TERMINAL EXTENDED, NMR, 20 STRUCTURES
分子名称: G-PROTEIN COUPLED RECEPTOR KINASE 2
著者Fushman, D, Cowburn, D.
登録日1997-11-21
公開日1998-02-25
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits.
J.Biol.Chem., 273, 1998
2MWS
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BU of 2mws by Molmil
Structure of the complex of ubiquitin and the ubiquitin-like (UBL) domain of Ddi1
分子名称: DNA damage-inducible protein 1, Ubiquitin
著者Fushman, D, Nowicka, U, Walker, O.
登録日2014-11-23
公開日2015-03-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
8F1F
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BU of 8f1f by Molmil
Structure of K48-linked tri-ubiquitin in complex with cyclic peptide
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Non-proteinogenic cyclic peptide (inhibitor), ...
著者Lubkowski, J, Fushman, D, Lemma, B.
登録日2022-11-05
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14, 2023
1A6S
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BU of 1a6s by Molmil
M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES
分子名称: GAG POLYPROTEIN
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D.
登録日1998-03-02
公開日1998-10-14
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus
J.Mol.Biol., 279, 1998
1C4B
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BU of 1c4b by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(RD-262)
分子名称: PROTEIN (CYCLO(RD-262))
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
登録日1999-08-02
公開日1999-08-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997
8E7O
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BU of 8e7o by Molmil
CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN
分子名称: SULFATE ION, Ubiquitin
著者Lemma, B.E, Fushman, D.
登録日2022-08-24
公開日2022-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14, 2023
1XBH
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BU of 1xbh by Molmil
A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262)
分子名称: PROTEIN (CYCLO(L-262))
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D.
登録日1999-02-17
公開日1999-02-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer
J.Am.Chem.Soc., 119, 1997
2BGF
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BU of 2bgf by Molmil
NMR structure of Lys48-linked di-ubiquitin using chemical shift perturbation data together with RDCs and 15N-relaxation data
分子名称: DI-UBIQUITIN
著者Van Dijk, A.D.J, Fushman, D, Bonvin, A.M.J.J.
登録日2004-12-22
公開日2005-08-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Various Strategies of Using Residual Dipolar Couplings in NMR-Driven Protein Docking: Application to Lys48-Linked Di-Ubiquitin and Validation Against 15N-Relaxation Data
Proteins: Struct., Funct., Bioinf., 60, 2005
1DDB
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BU of 1ddb by Molmil
STRUCTURE OF MOUSE BID, NMR, 20 STRUCTURES
分子名称: PROTEIN (BID)
著者Mcdonnell, J.M, Fushman, D, Milliman, C, Korsmeyer, S.J, Cowburn, D.
登録日1999-02-19
公開日1999-08-30
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists.
Cell(Cambridge,Mass.), 96, 1999
7UV5
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BU of 7uv5 by Molmil
The crystal structure of Papain-Like Protease of SARS CoV-2, C111S/D286N mutant, in complex with a Lys48-linked di-ubiquitin
分子名称: 1,2-ETHANEDIOL, Papain-like protease nsp3, Ubiquitin, ...
著者Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2022-04-29
公開日2022-05-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
5EMZ
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BU of 5emz by Molmil
Crystal structure of K48-linked diubiquitin with F45W mutation in the proximal unit
分子名称: Polyubiquitin-B, SULFATE ION
著者Nakasone, M.A, Paukstelis, P.J, Fushman, D.
登録日2015-11-07
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural characterization and practical fluorescence applications of the F45W ubiquitin mutant
To Be Published
1M30
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BU of 1m30 by Molmil
Solution structure of N-terminal SH3 domain from oncogene protein c-Crk
分子名称: Proto-oncogene C-crk
著者Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
登録日2002-06-26
公開日2003-08-05
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M3C
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BU of 1m3c by Molmil
Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk
分子名称: Proto-oncogene C-crk
著者Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
登録日2002-06-27
公開日2003-08-05
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M3B
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BU of 1m3b by Molmil
Solution structure of a circular form of the N-terminal SH3 domain (A134C, E135G, R191G mutant) from oncogene protein c-Crk.
分子名称: Proto-oncogene C-crk
著者Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
登録日2002-06-27
公開日2003-08-05
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M3A
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BU of 1m3a by Molmil
Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk.
分子名称: Proto-oncogene C-crk
著者Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
登録日2002-06-27
公開日2003-08-05
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
6OQ1
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BU of 6oq1 by Molmil
Crystal Structure of Branched K11/K48-Linked Tri-Ubiquitin
分子名称: Ubiquitin
著者Boughton, A.J, Fushman, D.
登録日2019-04-25
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Branching via K11 and K48 Bestows Ubiquitin Chains with a Unique Interdomain Interface and Enhanced Affinity for Proteasomal Subunit Rpn1.
Structure, 28, 2020
6OQ2
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BU of 6oq2 by Molmil
NMR Structure of Branched K11/K48-Linked Tri-Ubiquitin
分子名称: Ubiquitin
著者Boughton, A.J, Fushman, D.
登録日2019-04-25
公開日2019-10-23
最終更新日2020-01-22
実験手法SOLUTION NMR
主引用文献Branching via K11 and K48 Bestows Ubiquitin Chains with a Unique Interdomain Interface and Enhanced Affinity for Proteasomal Subunit Rpn1.
Structure, 28, 2020
2PE9
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BU of 2pe9 by Molmil
NMR Based Structure of the Open Conformation of LYS48-Linked Di-UBiquitin Using Experimental Global Rotational Diffusion Tensor from NMR Relaxation Measurements
分子名称: Ubiquitin
著者Ryabov, Y, Fushman, D.
登録日2007-04-02
公開日2007-07-10
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural assembly of multidomain proteins and protein complexes guided by the overall rotational diffusion tensor.
J.Am.Chem.Soc., 129, 2007
2PEA
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BU of 2pea by Molmil
NMR Based Structure of the Closed Conformation of LYS48-Linked Di-Ubiquitin Using Experimental Global Rotational Diffusion Tensor from NMR Relaxation Measurements
分子名称: Ubiquitin
著者Ryabov, Y, Fushman, D.
登録日2007-04-02
公開日2007-07-10
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural assembly of multidomain proteins and protein complexes guided by the overall rotational diffusion tensor.
J.Am.Chem.Soc., 129, 2007
5UJL
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BU of 5ujl by Molmil
Representative 1-conformer ensembles of K27-linked Ub2 from RDC data
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2017-01-18
公開日2017-10-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
5UJN
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BU of 5ujn by Molmil
Representative 2-conformer ensembles of K27-linked Ub2 from RDC data
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2017-01-18
公開日2018-08-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
7RBR
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BU of 7rbr by Molmil
The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with a Lys48-linked di-ubiquitin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Papain-like protease, ...
著者Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-07-06
公開日2021-09-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
3NS8
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BU of 3ns8 by Molmil
Crystal structure of an open conformation of Lys48-linked diubiquitin at pH 7.5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ubiquitin
著者Zhang, D, LaRonde-LeBlanc, N, Fushman, D.
登録日2010-07-01
公開日2011-07-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
7S6O
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BU of 7s6o by Molmil
The crystal structure of Lys48-linked di-ubiquitin
分子名称: ACETATE ION, Ubiquitin
著者Osipiuk, J, Tesar, C, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A.
登録日2021-09-14
公開日2021-09-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
2JY5
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BU of 2jy5 by Molmil
NMR structure of Ubiquilin 1 UBA domain
分子名称: Ubiquilin-1
著者Zhang, D, Raasi, S, Fushman, D.
登録日2007-12-06
公開日2008-03-18
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008

 

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