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5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
8DWY
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BU of 8dwy by Molmil
Chikungunya VLP in complex with neutralizing Fab CHK-265 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHK-265 heavy chain, CHK-265 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWX
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BU of 8dwx by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.C01 heavy chain, 506.C01 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DWW
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BU of 8dww by Molmil
Chikungunya VLP in complex with neutralizing Fab 506.A08 (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 506.A08 heavy chain, 506.A08 light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2022-08-02
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.
Sci Transl Med, 15, 2023
8DAN
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BU of 8dan by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.74 Å)
Cite:Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion
To Be Published
8DAQ
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BU of 8daq by Molmil
CryoEM structure of Western equine encephalitis virus VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2022-06-13
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion
To Be Published
5FFL
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BU of 5ffl by Molmil
Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2015-12-18
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Discovery of a proteinaceous cellular receptor for a norovirus.
Science, 353, 2016
6N08
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BU of 6n08 by Molmil
Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-11-06
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.916 Å)
Cite:Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2)
to be published
6MYM
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BU of 6mym by Molmil
Crystal structure of hemagglutinin from influenza virus A/Phillipines/2/1982 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-11-01
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of hemagglutinin from influenza virus A/Phillipines/2/1982 (H3N2)
To be published
6E47
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BU of 6e47 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid
Descriptor: 1,2-ETHANEDIOL, CMRF35-like molecule 1, GLYCOCHENODEOXYCHOLIC ACID, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-07-16
Release date:2018-09-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E48
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BU of 6e48 by Molmil
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
Descriptor: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-07-16
Release date:2018-09-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1ZOX
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BU of 1zox by Molmil
CLM-1 Mouse Myeloid Receptor Extracellular Domain
Descriptor: CLM-1
Authors:Nelson, C.N, Burton, R.L, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-05-15
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Mouse CLM-1 Ectodomain
To be Published
1ZTX
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BU of 1ztx by Molmil
West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab
Descriptor: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody
Authors:Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H.
Deposit date:2005-05-27
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of West Nile virus neutralization by a therapeutic antibody.
Nature, 437, 2005
7MKL
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BU of 7mkl by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
7MKM
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BU of 7mkm by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-38 Fv heavy chain, SARS2-38 Fv light chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-04-24
Release date:2021-05-12
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Immunity, 54, 2021
6V4O
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BU of 6v4o by Molmil
Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6V4N
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BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-11-28
Release date:2020-10-07
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6W37
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BU of 6w37 by Molmil
STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
Descriptor: ORF7a protein
Authors:Nelson, C.A, Minasov, G, Shuvalova, L, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-03-09
Release date:2020-04-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN
To be published
6C74
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BU of 6c74 by Molmil
Crystal Structure of Murine CD300lf in complex with phosphocholine
Descriptor: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.358 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C6Q
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BU of 6c6q by Molmil
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1XAU
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BU of 1xau by Molmil
STRUCTURE OF THE BTLA ECTODOMAIN
Descriptor: B- and T-lymphocyte attenuator, CADMIUM ION
Authors:Nelson, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-08-26
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.
J.Immunol., 180, 2008
5KVG
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BU of 5kvg by Molmil
Zika specific antibody, ZV-67, bound to ZIKA envelope DIII
Descriptor: CHLORIDE ION, ZIKA Envelope DIII, ZV-67 Antibody Fab Heavy Chain, ...
Authors:Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-14
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVF
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BU of 5kvf by Molmil
Zika specific antibody, ZV-64, bound to ZIKA envelope DIII
Descriptor: GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ...
Authors:Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-14
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVE
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BU of 5kve by Molmil
Zika specific antibody, ZV-48, bound to ZIKA envelope DIII
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Genome polyprotein, ...
Authors:Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-14
Release date:2016-08-10
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016
5KVD
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BU of 5kvd by Molmil
Zika specific antibody, ZV-2, bound to ZIKA envelope DIII
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ...
Authors:Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-07-14
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis of Zika Virus-Specific Antibody Protection.
Cell, 166, 2016

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