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3VD7
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BU of 3vd7 by Molmil
E. coli (lacZ) beta-galactosidase (N460S) in complex with galactotetrazole
Descriptor: (5R, 6S, 7S, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VDB
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BU of 3vdb by Molmil
E. coli (lacZ) beta-galactosidase (N460T) in complex with galactonolactone
Descriptor: Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VDA
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BU of 3vda by Molmil
E. coli (lacZ) beta-galactosidase (N460T)
Descriptor: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD5
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BU of 3vd5 by Molmil
E. coli (lacZ) beta-galactosidase (N460S)
Descriptor: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
3VD4
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BU of 3vd4 by Molmil
E. coli (lacZ) beta-galactosidase (N460D) in complex with IPTG
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
Authors:Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys., 521, 2012
6WCV
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BU of 6wcv by Molmil
Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase
Descriptor: (3S,5S,9R,20R,21R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,20, 21-pentahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-oic acid 3,5-dioxide (non-preferred name), Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2020-03-31
Release date:2020-07-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Tartryl-CoA inhibits succinyl-CoA synthetase
Acta Crystallogr.,Sect.F, 76, 2020
2NRC
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BU of 2nrc by Molmil
C28A Mutant of Succinyl-CoA:3-Ketoacid CoA Transferase from Pig Heart
Descriptor: Succinyl-CoA:3-ketoacid-coenzyme A transferase 1
Authors:Tammam, S.D, Fraser, M.E.
Deposit date:2006-11-01
Release date:2007-09-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Identification of the Cysteine Residue Exposed by the Conformational Change in Pig Heart Succinyl-CoA:3-Ketoacid Coenzyme A Transferase on Binding Coenzyme A.
Biochemistry, 46, 2007
2NRB
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BU of 2nrb by Molmil
C28S Mutant of Succinyl-CoA:3-Ketoacid CoA Transferase from Pig Heart
Descriptor: CHLORIDE ION, Succinyl-CoA:3-ketoacid-coenzyme A transferase 1
Authors:Tammam, S.D, Fraser, M.E.
Deposit date:2006-11-01
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of the Cysteine Residue Exposed by the Conformational Change in Pig Heart Succinyl-CoA:3-Ketoacid Coenzyme A Transferase on Binding Coenzyme A.
Biochemistry, 46, 2007
7JMK
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BU of 7jmk by Molmil
GTP-specific succinyl-CoA synthetase complexed with Mg-GDP in space group P32
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2020-08-01
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
7JKR
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BU of 7jkr by Molmil
GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPNP, phosphohistidine loop pointing towards nucleotide binding site
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2020-07-28
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
7JFP
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BU of 7jfp by Molmil
GTP-specific succinyl-CoA synthetase complexed with Mg-GDP, phosphohistidine loop pointing towards nucleotide binding site
Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2020-07-17
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
7JJ0
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BU of 7jj0 by Molmil
GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPCP
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2020-07-24
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase
Acta Crystallogr.,Sect.D, 77, 2021
7LI0
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BU of 7li0 by Molmil
Crystal structure of apo Moraxella catarrhalis ferric binding protein A in an open conformation
Descriptor: CARBONATE ION, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Chan, C, Ng, D, Fraser, M.E, Schryvers, A.B.
Deposit date:2021-01-26
Release date:2022-02-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens.
Biometals, 2022
7LI1
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BU of 7li1 by Molmil
Crystal structure of holo Moraxella catarrhalis ferric binding protein A in an open conformation
Descriptor: CARBONATE ION, FE (III) ION, Fe(3+) ABC transporter substrate-binding protein
Authors:Chan, C, Ng, D, Fraser, M.E, Schryvers, A.B.
Deposit date:2021-01-26
Release date:2022-02-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens.
Biometals, 2022
6NO3
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BU of 6no3 by Molmil
ADP bound to V113bL mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.939 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO6
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BU of 6no6 by Molmil
K46bE&K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: Succinate--CoA ligase [ADP-forming] subunit beta
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO1
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BU of 6no1 by Molmil
ADP bound to K46bE mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Succinate--CoA ligase [ADP-forming] subunit beta
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO4
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BU of 6no4 by Molmil
ADP bound to L227bF mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Succinate--CoA ligase [ADP-forming] subunit beta
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO5
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BU of 6no5 by Molmil
ADP bound to K46bE&K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AMMONIUM ION, MAGNESIUM ION, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.069 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO2
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BU of 6no2 by Molmil
ADP bound to K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.159 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NO0
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BU of 6no0 by Molmil
ADP bound to ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huang, J, Fraser, M.E.
Deposit date:2019-01-15
Release date:2019-07-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis.
Acta Crystallogr D Struct Biol, 75, 2019
6NZY
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BU of 6nzy by Molmil
Structural Determination of the Carboxy-terminal portion of ATP-citrate lyase
Descriptor: ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, GLYCEROL, ...
Authors:Nguyen, V.H, Fraser, M.E.
Deposit date:2019-02-14
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of the active site residues in ATP-citrate lyase's carboxy-terminal portion.
Protein Sci., 28, 2019
5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
Descriptor: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TET
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BU of 5tet by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate
Descriptor: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDZ
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BU of 5tdz by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-20
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017

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