ADP bound to K46bE&K114bD mutant ATP-grasp fold of Blastocystis hominis succinyl-CoA synthetase

Summary for 6NO5

DescriptorSuccinate--CoA ligase [ADP-forming] subunit beta, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsdouble mutation, complex, ligase
Biological sourceBlastocystis sp. subtype 1 (strain ATCC 50177 / NandII)
Total number of polymer chains4
Total molecular weight112265.77
Huang, J.,Fraser, M.E. (deposition date: 2019-01-15, release date: 2019-07-17)
Primary citation
Huang, J.,Nguyen, V.H.,Hamblin, K.A.,Maytum, R.,van der Glezen, M.,Fraser, M.E.
ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis
Acta Crystallogr.,Sect.D, 75:647-659, 2019
DOI: 10.1107/S2059798319007976
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22220 1.0% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution