7KUI
 
 | | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. CIC region of a cluster identified by 3-dimensional variability analysis in cryoSPARC. | | Descriptor: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | | Authors: | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | | Deposit date: | 2020-11-25 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Commun Biol, 4, 2021
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7KU7
 | | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. Cluster identified by 3-dimensional variability analysis in cryoSPARC. | | Descriptor: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | | Authors: | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | | Deposit date: | 2020-11-24 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Commun Biol, 4, 2021
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7KVF
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6UW6
 | | Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc | | Descriptor: | Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | Authors: | Deng, Z, Yuan, P. | | Deposit date: | 2019-11-04 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
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6UW9
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6UW4
 | | Cryo-EM structure of human TRPV3 determined in lipid nanodisc | | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | Authors: | Deng, Z, Yuan, P. | | Deposit date: | 2019-11-04 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
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6V6D
 | | Cryo-EM structure of human pannexin 1 | | Descriptor: | Pannexin-1 | | Authors: | Deng, Z, He, Z, Yuan, P. | | Deposit date: | 2019-12-05 | | Release date: | 2020-04-01 | | Last modified: | 2020-04-22 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Cryo-EM structures of the ATP release channel pannexin 1.
Nat.Struct.Mol.Biol., 27, 2020
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6UW8
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6UZY
 | | Cryo-EM structure of Xenopus tropicalis pannexin 1 | | Descriptor: | HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | Authors: | Deng, Z, He, Z, Yuan, P. | | Deposit date: | 2019-11-15 | | Release date: | 2020-04-01 | | Last modified: | 2020-04-22 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Cryo-EM structures of the ATP release channel pannexin 1.
Nat.Struct.Mol.Biol., 27, 2020
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6VXN
 | | Cryo-EM structure of Arabidopsis thaliana MSL1 A320V | | Descriptor: | DODECANE, Mechanosensitive ion channel protein 1, mitochondrial | | Authors: | Deng, Z, Zhang, J, Yuan, P. | | Deposit date: | 2020-02-22 | | Release date: | 2020-08-05 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance.
Nat Commun, 11, 2020
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6VXM
 | | Cryo-EM structure of Arabidopsis thaliana MSL1 | | Descriptor: | EICOSANE, Mechanosensitive ion channel protein 1, mitochondrial | | Authors: | Deng, Z, Zhang, J, Yuan, P. | | Deposit date: | 2020-02-22 | | Release date: | 2020-08-05 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance.
Nat Commun, 11, 2020
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6VXP
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8F7C
 | | Cryo-EM structure of human pannexin 2 | | Descriptor: | Pannexin-2, Soluble cytochrome b562 fusion | | Authors: | He, Z, Yuan, P. | | Deposit date: | 2022-11-18 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.92 Å) | | Cite: | Structural and functional analysis of human pannexin 2 channel.
Nat Commun, 14, 2023
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8F32
 | | ELIC with Propylamine in SMA nanodiscs with 2:1:1 POPC:POPE:POPG | | Descriptor: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | Authors: | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | Deposit date: | 2022-11-09 | | Release date: | 2023-11-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
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8F35
 | | Apo ELIC in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG | | Descriptor: | Erwinia chrysanthemi ligand-gated ion channel | | Authors: | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | Deposit date: | 2022-11-09 | | Release date: | 2023-11-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
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8F33
 | | ELIC with Propylamine in saposin nanodiscs with 2:1:1 POPC:POPE:POPG | | Descriptor: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | Authors: | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | Deposit date: | 2022-11-09 | | Release date: | 2023-11-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
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8F34
 | | ELIC with Propylamine in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG | | Descriptor: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | | Authors: | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | | Deposit date: | 2022-11-09 | | Release date: | 2023-11-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
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8FPT
 | | STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | | Descriptor: | Alpha-synuclein | | Authors: | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | | Deposit date: | 2023-01-05 | | Release date: | 2023-02-22 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Biorxiv, 2023
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