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1A9N
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BU of 1a9n by Molmil
CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA
Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A'
Authors:Price, S.R, Evans, P.R, Nagai, K.
Deposit date:1998-04-08
Release date:1998-09-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA.
Nature, 394, 1998
1BB9
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BU of 1bb9 by Molmil
CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2
Descriptor: AMPHIPHYSIN 2
Authors:Owen, D.J, Mcmahon, H.T, Evans, P.R.
Deposit date:1998-04-29
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.
EMBO J., 17, 1998
1B9K
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BU of 1b9k by Molmil
ALPHA-ADAPTIN APPENDAGE DOMAIN, FROM CLATHRIN ADAPTOR AP2
Descriptor: PROTEIN (ALPHA-ADAPTIN APPENDAGE DOMAIN)
Authors:Owen, D.J, Evans, P.R.
Deposit date:1999-02-11
Release date:1999-07-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.
Cell(Cambridge,Mass.), 97, 1999
1BXX
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BU of 1bxx by Molmil
MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH TGN38 INTERNALIZATION PEPTIDE DYQRLN
Descriptor: PROTEIN (AP50), PROTEIN (TGN38 PEPTIDE)
Authors:Owen, D.J, Evans, P.R.
Deposit date:1998-10-08
Release date:1998-11-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
1BW8
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BU of 1bw8 by Molmil
MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM
Descriptor: PROTEIN (INTERNALIZATION SIGNAL FROM EGFR), PROTEIN (MU2 ADAPTIN SUBUNIT)
Authors:Owen, D.J, Evans, P.R.
Deposit date:1998-09-30
Release date:1998-11-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A structural explanation for the recognition of tyrosine-based endocytotic signals.
Science, 282, 1998
2YNO
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BU of 2yno by Molmil
yeast betaprime COP 1-304H6
Descriptor: COATOMER SUBUNIT BETA', POLY ALA
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012
2YNP
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BU of 2ynp by Molmil
yeast betaprime COP 1-604 with KTKTN motif
Descriptor: COATOMER SUBUNIT BETA', KTKTN MOTIF
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.962 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012
2YNN
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BU of 2ynn by Molmil
yeast betaprime COP 1-304 with KTKTN motif
Descriptor: COATOMER SUBUNIT BETA', KTKTN MOTIF, SULFATE ION
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012
1HFA
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BU of 1hfa by Molmil
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein, PI(4,5)P2 complex
Descriptor: CLATHRIN ASSEMBLY PROTEIN SHORT FORM, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:2000-11-30
Release date:2001-02-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Science, 291, 2001
1H0A
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BU of 1h0a by Molmil
Epsin ENTH bound to Ins(1,4,5)P3
Descriptor: 1,4-DIETHYLENE DIOXIDE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, EPSIN
Authors:Ford, M.G.J, McMahon, H.T, Evans, P.R.
Deposit date:2002-06-12
Release date:2002-10-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Curvature of Clathrin-Coated Pits Driven by Epsin
Nature, 419, 2002
1HF8
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BU of 1hf8 by Molmil
CALM-N N-terminal domain of clathrin assembly lymphoid myeloid leukaemia protein
Descriptor: CLATHRIN ASSEMBLY PROTEIN SHORT FORM
Authors:Ford, M.G.J, Evans, P.R, McMahon, H.T.
Deposit date:2000-11-30
Release date:2001-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Simultaneous Binding of Ptdins(4,5)P2 and Clathrin by Ap180 in the Nucleation of Clathrin Lattices on Membranes
Science, 291, 2001
1HKQ
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BU of 1hkq by Molmil
PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain.
Descriptor: BENZOIC ACID, MERCURY (II) ION, PHOSPHATE ION, ...
Authors:Giraldo, R, Fernandez-Tornero, C, Evans, P.R, Diaz-Orejas, R, Romero, A.
Deposit date:2003-03-11
Release date:2003-05-29
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain
Nat.Struct.Biol., 10, 2003
5C7Z
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BU of 5c7z by Molmil
AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
Descriptor: AP-2 complex subunit mu, Integrin alpha-4
Authors:Owen, D.J, Evans, P.R, Wilson, T.A.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
6QH7
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BU of 6qh7 by Molmil
AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
Authors:Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
2C5J
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BU of 2c5j by Molmil
N-terminal domain of tlg1, domain-swapped dimer
Descriptor: T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1
Authors:Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B.
Deposit date:2005-10-27
Release date:2006-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of the Interaction between the Snare Tlg1 and Vps51.
Traffic, 7, 2006
2C5K
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BU of 2c5k by Molmil
N-terminal domain of tlg1 complexed with N-terminus of vps51
Descriptor: SULFATE ION, T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1, VACUOLAR PROTEIN SORTING PROTEIN 51
Authors:Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B.
Deposit date:2005-10-27
Release date:2006-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Analysis of the Interaction between the Snare Tlg1 and Vps51.
Traffic, 7, 2006
2BP5
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BU of 2bp5 by Molmil
MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Descriptor: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4
Authors:Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D.
Deposit date:2005-04-18
Release date:2005-07-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
2C5I
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BU of 2c5i by Molmil
N-terminal domain of tlg1 complexed with N-terminus of vps51 in distorted conformation
Descriptor: SULFATE ION, T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1, VACUOLAR PROTEIN SORTING PROTEIN 51
Authors:Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B.
Deposit date:2005-10-27
Release date:2006-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Analysis of the Interaction between the Snare Tlg1 and Vps51.
Traffic, 7, 2006
2C08
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BU of 2c08 by Molmil
Rat endophilin A1 BAR domain
Descriptor: SH3-CONTAINING GRB2-LIKE PROTEIN 2
Authors:Gallop, J.L, Kent, H.M, Mcmahon, H.T, Evans, P.R.
Deposit date:2005-08-26
Release date:2006-06-14
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of Endophilin N-Bar Domain-Mediated Membrane Curvature.
Embo J., 25, 2006
1URN
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BU of 1urn by Molmil
U1A MUTANT/RNA COMPLEX + GLYCEROL
Descriptor: CHLORIDE ION, GLYCEROL, PROTEIN (U1A), ...
Authors:Oubridge, C, Ito, N, Evans, P.R, Teo, C.-H, Nagai, K.
Deposit date:1995-01-04
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin.
Nature, 372, 1994
1UTC
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BU of 1utc by Molmil
Clathrin terminal domain complexed with TLPWDLWTT
Descriptor: AMPHIPHYSIN, CLATHRIN HEAVY CHAIN
Authors:Miele, A.E, Evans, P.R, Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
7OIT
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BU of 7oit by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OG1
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BU of 7og1 by Molmil
AP2 clathrin adaptor core in complex with cargo peptide and FCHO2
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-05
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OHO
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BU of 7oho by Molmil
Crystal structure of AP2 FCHO2 chimera
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ...
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-11
Release date:2022-06-01
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
7OIQ
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BU of 7oiq by Molmil
Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form)
Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2
Authors:Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J.
Deposit date:2021-05-12
Release date:2022-06-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022

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