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1N7S
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High Resolution Structure of a Truncated Neuronal SNARE Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, SNAP-25A, ...
著者Ernst, J.A, Brunger, A.T.
登録日2002-11-16
公開日2002-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High Resolution Structure, Stability, and Synaptotagmin Binding of a Truncated Neuronal SNARE Complex
J.Biol.Chem., 278, 2003
1DQV
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BU of 1dqv by Molmil
CRYSTAL STRUCTURE OF SYNAPTOTAGMIN III C2A/C2B
分子名称: MAGNESIUM ION, SULFATE ION, SYNAPTOTAGMIN III
著者Sutton, R.B, Ernst, J.A, Brunger, A.T.
登録日2000-01-05
公開日2000-01-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction.
J.Cell Biol., 147, 1999
1IHV
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BU of 1ihv by Molmil
SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: HIV-1 INTEGRASE
著者Clore, G.M, Lodi, P.J, Ernst, J.A, Gronenborn, A.M.
登録日1995-05-12
公開日1996-10-14
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry, 34, 1995
1IHW
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BU of 1ihw by Molmil
SOLUTION STRUCTURE OF THE DNA BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, 40 STRUCTURES
分子名称: HIV-1 INTEGRASE
著者Clore, G.M, Lodi, P.J, Ernst, J.A, Gronenborn, A.M.
登録日1995-05-12
公開日1996-07-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry, 34, 1995
3HN8
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BU of 3hn8 by Molmil
Crystal structure of synaptotagmin
分子名称: CALCIUM ION, Synaptotagmin-3, ZINC ION
著者Strop, P, Vrljic, M, Ernst, J, Brunger, A.T.
登録日2009-05-30
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.
Nat.Struct.Mol.Biol., 17, 2010
5VZY
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BU of 5vzy by Molmil
Crystal structure of crenezumab Fab in complex with Abeta
分子名称: Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain
著者Ultsch, M, Wang, W.
登録日2017-05-29
公開日2017-08-09
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
5VZX
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Crystal structure of crenezumab Fab
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Crenezumab Fab heavy chain, ...
著者Ultsch, M, Wang, W.
登録日2017-05-29
公開日2017-08-09
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
6N9T
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Structure of a peptide-based photo-affinity cross-linker with Herceptin Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin G1 FC, ...
著者Sadowsky, J, Ultsch, M, Vance, N, Wang, W.
登録日2018-12-04
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.576 Å)
主引用文献Development, Optimization, and Structural Characterization of an Efficient Peptide-Based Photoaffinity Cross-Linking Reaction for Generation of Homogeneous Conjugates from Wild-Type Antibodies.
Bioconjug. Chem., 30, 2019
5UQV
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USP7 in complex with GNE6640 (4-(2-amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl)phenol)
分子名称: 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl]phenol, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2017-02-08
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature, 550, 2017
5UQX
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USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide)
分子名称: 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl[3,3'-bipyridine]-6-carboxamide, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2017-02-08
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature, 550, 2017
5J7T
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Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation
分子名称: Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-04-06
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2001 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
5JTJ
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USP7CD-CTP in complex with Ubiquitin
分子名称: CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
5JTV
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USP7CD-UBL45 in complex with Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.312 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
1JQD
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Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine
分子名称: HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X.
登録日2001-08-06
公開日2002-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1JQE
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Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine
分子名称: Histamine N-Methyltransferase, QUINACRINE, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X.
登録日2001-08-06
公開日2002-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001

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件を2024-05-01に公開中

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