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8THO
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BU of 8tho by Molmil
Solution structure of the zinc finger repeat domain of BCL11A (ZnF456)
Descriptor: B-cell lymphoma/leukemia 11A, ZINC ION
Authors:Viennet, T, Yin, M, Orkin, S.H, Arthanari, H.
Deposit date:2023-07-17
Release date:2024-07-24
Method:SOLUTION NMR
Cite:Structural and dynamic investigation of DNA-binding by BCL11A reveals a specific role for ZnF6
To Be Published
6WO1
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BU of 6wo1 by Molmil
Hybrid acetohydroxyacid synthase complex structure with Cryptococcus neoformans AHAS catalytic subunit and Saccharomyces cerevisiae AHAS regulatory subunit
Descriptor: 2-methylpyrimidin-4-amine, Acetohydroxyacid synthase catalytic subunit, Acetohydroxyacid synthase regulatory subunit, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2020-04-23
Release date:2020-07-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
6U9D
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BU of 6u9d by Molmil
Saccharomyces cerevisiae acetohydroxyacid synthase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Acetolactate synthase catalytic subunit, mitochondrial, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2019-09-08
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Structures of fungal and plant acetohydroxyacid synthases.
Nature, 586, 2020
5WJ1
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BU of 5wj1 by Molmil
Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
Descriptor: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, Acetolactate synthase, ...
Authors:Garcia, M.D, Lonhienne, T, Guddat, L.W.
Deposit date:2017-07-21
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural insights into the mechanism of inhibition of AHAS by herbicides.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BD3
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BU of 6bd3 by Molmil
Saccharomyces cerevisiae acetohydroxyacid synthase
Descriptor: 2-ACETYL-THIAMINE DIPHOSPHATE, ACETATE ION, Acetolactate synthase catalytic subunit, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2017-10-21
Release date:2017-11-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism
Chemistryselect, 2017
6BD9
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BU of 6bd9 by Molmil
Saccharomyces cerevisiae acetohydroxyacid synthase
Descriptor: Acetolactate synthase catalytic subunit, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2017-10-22
Release date:2017-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.982 Å)
Cite:High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism
Chemistryselect, 2017
5FEM
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BU of 5fem by Molmil
Saccharomyces cerevisiae Acetohydroxyacid Synthase in complex with bensulfuron methyl
Descriptor: Acetolactate synthase catalytic subunit, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2015-12-17
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase.
Angew.Chem.Int.Ed.Engl., 55, 2016
6RBD
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BU of 6rbd by Molmil
State 1 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles
Descriptor: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C.
Deposit date:2019-04-10
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.
Nat Commun, 10, 2019
6RBE
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BU of 6rbe by Molmil
State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C.
Deposit date:2019-04-10
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.
Nat Commun, 10, 2019
8EPZ
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BU of 8epz by Molmil
Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mn
Descriptor: BICARBONATE ION, CARBON DIOXIDE, Dihydroxyacid dehydratase, ...
Authors:Bayaraa, T, Lonhienne, T, Guddat, L.W.
Deposit date:2022-10-07
Release date:2023-02-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mg
To Be Published
8EJ0
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BU of 8ej0 by Molmil
Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mg
Descriptor: BICARBONATE ION, CARBON DIOXIDE, Dihydroxyacid dehydratase, ...
Authors:Bayaraa, T, Lonhienne, T, Guddat, L.W.
Deposit date:2022-09-16
Release date:2023-08-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of Fe-S cluster-dependent dehydratase from Paralcaligenes ureilyticus in complex with Mg
To Be Published
8VIS
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BU of 8vis by Molmil
Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Fraser, B.J, Dong, A, Ilyassov, O, Kenney, T, Li, Y.Y, Seitova, A, Li, Y, Hejazi, Z, Edwards, A, Benard, F, Arrowsmith, C.
Deposit date:2024-01-05
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide
To Be Published
5IMS
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BU of 5ims by Molmil
Saccharomyces cerevisiae acetohydroxyacid synthase
Descriptor: ACETATE ION, Acetolactate synthase catalytic subunit, mitochondrial, ...
Authors:Guddat, L.W, Lonhienne, T.
Deposit date:2016-03-06
Release date:2017-02-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.984 Å)
Cite:A hidden redox cycle controls catalysis in acetohydroxyacid synthase
To Be Published
5K6Q
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BU of 5k6q by Molmil
Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase catalytic subunit
Descriptor: 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
Authors:Garcia, M.D, Wang, J.-G, Lonhienne, T, Guddat, L.W.
Deposit date:2016-05-25
Release date:2017-05-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.952 Å)
Cite:Crystal structure of plant acetohydroxyacid synthase, the target for several commercial herbicides.
FEBS J., 284, 2017
8SXD
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BU of 8sxd by Molmil
Campylobacter jejuni keto-acid reductoisomerase in complex with intermediate and NADP+
Descriptor: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
Authors:Lin, X, Lonhienne, T, Guddat, L.W.
Deposit date:2023-05-21
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8SWM
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BU of 8swm by Molmil
Crystal structure of Campylobacter jejuni ketol-acid reductoisomerase in complex with 2-acetolactate
Descriptor: (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase (NADP(+)), ...
Authors:Lin, X, Lonhienne, T, Guddat, L.W.
Deposit date:2023-05-19
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPP
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BU of 8upp by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADPH and Hoe704
Descriptor: (2R)-(dimethylphosphoryl)(hydroxy)acetic acid, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
Authors:Lin, X, Lv, Y, Lonhienne, T, Guddat, L.W.
Deposit date:2023-10-23
Release date:2024-04-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPN
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BU of 8upn by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with NADP+ and HMKB
Descriptor: 3-hydroxy-3-methyl-2-oxobutanoic acid, CHLORIDE ION, Ketol-acid reductoisomerase, ...
Authors:Lin, X, Lonhienne, T, Guddat, L.W.
Deposit date:2023-10-23
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
8UPQ
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BU of 8upq by Molmil
Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate.
Descriptor: (2R)-2,3-dihydroxy-3-methylbutanoic acid, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION
Authors:Lin, X, Lonhienne, T, Guddat, L.W.
Deposit date:2023-10-23
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase
Acs Catalysis, 2024
3GUU
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BU of 3guu by Molmil
X-ray structure of Candida Antarctica lipase A
Descriptor: GLYCEROL, Lipase A, PENTAETHYLENE GLYCOL, ...
Authors:Brandt, A.-M, Li, X.-G, Nymalm-Rejstrom, Y, Airenne, T, Kanerva, L.T, Salminen, T.A.
Deposit date:2009-03-30
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of Lipase A from Candida antarctica
To be Published
4ZM1
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BU of 4zm1 by Molmil
Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - wild type
Descriptor: CITRIC ACID, Chain length determinant protein, MAGNESIUM ION
Authors:Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R.
Deposit date:2015-05-02
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri.
Plos One, 10, 2015
4ZM5
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BU of 4zm5 by Molmil
Shigella flexneri lipopolysaccharide O-antigen chain-length regulator WzzBSF - A107P mutant
Descriptor: CHLORIDE ION, Chain length determinant protein, MAGNESIUM ION
Authors:Ericsson, D.J, Chang, C.-W, Lonhienne, T, Casey, L, Benning, F, Kobe, B, Tran, E.N.H, Morona, R.
Deposit date:2015-05-02
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri.
Plos One, 10, 2015
4AD4
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BU of 4ad4 by Molmil
Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-isofagomine and alpha-1,2- mannobiose
Descriptor: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCOSYL HYDROLASE FAMILY 71, alpha-D-glucopyranose, ...
Authors:Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AD2
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BU of 4ad2 by Molmil
Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-isofagomine
Descriptor: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCOSYL HYDROLASE FAMILY 71, alpha-D-glucopyranose
Authors:Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ACY
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BU of 4acy by Molmil
Selenomethionine derivative of the GH99 endo-alpha-mannosidase from Bacteroides thetaiotaomicron
Descriptor: ENDO-ALPHA-MANNOSIDASE, FORMIC ACID, GLYCEROL
Authors:Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J.
Deposit date:2011-12-21
Release date:2012-02-01
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012

 

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