1MVK
| X-ray structure of the tetrameric mutant of the B1 domain of streptococcal protein G | Descriptor: | Immunoglobulin G binding protein G, SULFATE ION | Authors: | Frank, M.K, Dyda, F, Dobrodumov, A, Gronenborn, A.M. | Deposit date: | 2002-09-25 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Core mutations switch monomeric protein GB1 into an intertwined tetramer. Nat.Struct.Biol., 9, 2002
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1F1Z
| TNSA, a catalytic component of the TN7 transposition system | Descriptor: | CHLORIDE ION, MAGNESIUM ION, TNSA ENDONUCLEASE | Authors: | Hickman, A.B, Li, Y, Mathew, S.V, May, E.W, Craig, N.L, Dyda, F. | Deposit date: | 2000-05-21 | Release date: | 2000-06-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Unexpected structural diversity in DNA recombination: the restriction endonuclease connection. Mol.Cell, 5, 2000
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1IB1
| CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX | Descriptor: | 14-3-3 ZETA ISOFORM, COA-S-ACETYL TRYPTAMINE, SEROTONIN N-ACETYLTRANSFERASE | Authors: | Obsil, T, Ghirlando, R, Klein, D.C, Ganguly, S, Dyda, F. | Deposit date: | 2001-03-26 | Release date: | 2001-05-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation. Cell(Cambridge,Mass.), 105, 2001
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1RZ9
| Crystal Structure of AAV Rep complexed with the Rep-binding sequence | Descriptor: | 26-MER, Rep protein | Authors: | Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F. | Deposit date: | 2003-12-24 | Release date: | 2004-02-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces. Mol.Cell, 13, 2004
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1T0F
| Crystal Structure of the TnsA/TnsC(504-555) complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MALONIC ACID, ... | Authors: | Ronning, D.R, Li, Y, Perez, Z.N, Ross, P.D, Hickman, A.B, Craig, N.L, Dyda, F. | Deposit date: | 2004-04-08 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA. Embo J., 23, 2004
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6X68
| Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP) | Descriptor: | CALCIUM ION, Transposase, ZINC ION, ... | Authors: | Chen, Q, Hickman, A.B, Dyda, F. | Deposit date: | 2020-05-27 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Structural basis of seamless excision and specific targeting by piggyBac transposase Nat Commun, 11, 2020
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6XG8
| ISCth4 transposase, pre-cleaved complex, PCC | Descriptor: | DNA (26-MER), Mutator family transposase | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-17 | Release date: | 2020-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
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6XGW
| ISCth4 transposase, pre-reaction complex, PRC | Descriptor: | DNA (32-MER), Mutator family transposase | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
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6X67
| Cryo-EM structure of piggyBac transposase strand transfer complex (STC) | Descriptor: | CALCIUM ION, DNA (37-MER), DNA (47-MER), ... | Authors: | Chen, Q, Hickman, A.B, Dyda, F. | Deposit date: | 2020-05-27 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural basis of seamless excision and specific targeting by piggyBac transposase Nat Commun, 11, 2020
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6XGX
| ISCth4 transposase, strand transfer complex 1, STC1 | Descriptor: | DNA (21-MER), DNA (25-MER), DNA (47-MER), ... | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
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1AER
| DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD | Descriptor: | 2-(1,5-DIDEOXYRIBOSE)-4-AMIDO-THIAZOLE, ADENOSINE MONOPHOSPHATE, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... | Authors: | Li, M, Dyda, F, Benhar, I, Pastan, I, Davies, D.R. | Deposit date: | 1995-12-11 | Release date: | 1996-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation Proc.Natl.Acad.Sci.USA, 93, 1996
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1BIS
| HIV-1 INTEGRASE CORE DOMAIN | Descriptor: | HIV-1 INTEGRASE | Authors: | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | Deposit date: | 1998-06-19 | Release date: | 1998-08-19 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
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1BIU
| HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++ | Descriptor: | HIV-1 INTEGRASE, MAGNESIUM ION | Authors: | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | Deposit date: | 1998-06-19 | Release date: | 1998-08-19 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
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1BIZ
| HIV-1 INTEGRASE CORE DOMAIN | Descriptor: | CACODYLATE ION, HIV-1 INTEGRASE | Authors: | Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R. | Deposit date: | 1998-06-21 | Release date: | 1998-08-19 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95, 1998
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2BW3
| Three-dimensional structure of the Hermes DNA transposase | Descriptor: | TRANSPOSASE | Authors: | Hickman, A.B, Perez, Z.N, Zhou, L, Musingarimi, P, Ghirlando, R, Hinshaw, J.E, Craig, N.L, Dyda, F. | Deposit date: | 2005-07-11 | Release date: | 2005-07-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Architecture of a Eukaryotic DNA Transposase Nat.Struct.Mol.Biol., 12, 2005
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2BZF
| Structural basis for DNA bridging by barrier-to-autointegration factor (BAF) | Descriptor: | 5'-D(*CP*CP*TP*CP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*GP*AP*GP*GP)-3', BARRIER-TO-AUTOINTEGRATION FACTOR | Authors: | Bradley, C.M, Ronning, D.R, Ghirlando, R, Craigie, R, Dyda, F. | Deposit date: | 2005-08-16 | Release date: | 2005-09-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Structural Basis for DNA Bridging by Barrier-to-Autointegration Factor. Nat.Struct.Mol.Biol., 12, 2005
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1YQV
| The crystal structure of the antibody Fab HyHEL5 complex with lysozyme at 1.7A resolution | Descriptor: | Hen Egg White Lysozyme, HyHEL-5 Antibody Heavy Chain, HyHEL-5 Antibody Light Chain | Authors: | Cohen, G.H, Silverton, E.W, Padlan, E.A, Dyda, F, Wibbenmeyer, J.A, Wilson, R.C, Davies, D.R. | Deposit date: | 2005-02-02 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry. Acta Crystallogr.,Sect.D, 61, 2005
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2A6O
| Crystal Structure of the ISHp608 Transposase in Complex with Stem-loop DNA | Descriptor: | 5'-D(*CP*CP*CP*CP*TP*AP*GP*CP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*GP*A)-3', ISHp608 Transposase | Authors: | Ronning, D.R, Guynet, C, Ton-Hoang, B, Perez, Z.N, Ghirlando, R, Chandler, M, Dyda, F. | Deposit date: | 2005-07-03 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Active site sharing and subterminal hairpin recognition in a new class of DNA transposases. Mol.Cell, 20, 2005
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2A6M
| Crystal Structure of the ISHp608 Transposase | Descriptor: | ISHp608 transposase | Authors: | Ronning, D.R, Guynet, C, Ton-Hoang, B, Perez, Z.N, Ghirlando, R, Chandler, M, Dyda, F. | Deposit date: | 2005-07-03 | Release date: | 2005-10-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Active site sharing and subterminal hairpin recognition in a new class of DNA transposases. Mol.Cell, 20, 2005
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2X2F
| Dynamin 1 GTPase dimer, short axis form | Descriptor: | DYNAMIN-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Chappie, J.S, Acharya, S, Leonard, M, Schmid, S.L, Dyda, F. | Deposit date: | 2010-01-13 | Release date: | 2010-04-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity. Nature, 465, 2010
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2XM3
| Deinococcus radiodurans ISDra2 Transposase Left end DNA complex | Descriptor: | 5'-D(*TP*TP*AP*GP*T)-3', ACETATE ION, DRA2 TRANSPOSASE BINDING ELEMENT, ... | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-07-22 | Release date: | 2010-10-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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2XO6
| DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE Y132F MUTANT COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE | Descriptor: | 5'-D(*TP*TP*GP*AP*TP*G)-3', ACETATE ION, CADMIUM ION, ... | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-08-09 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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2XQC
| DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN | Descriptor: | 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ... | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-09-01 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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2XMA
| DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE RIGHT END DNA COMPLEX | Descriptor: | DRA2 TRANSPOSASE RIGHT END RECOGNITION SITE, MAGNESIUM ION, TRANSPOSASE | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-07-26 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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2VJV
| Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site | Descriptor: | 5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3', 5'-D(*DT*DA*DT*DT*DA*DCP)-3', MAGNESIUM ION, ... | Authors: | Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F. | Deposit date: | 2007-12-13 | Release date: | 2008-02-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection. Cell(Cambridge,Mass.), 132, 2008
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