5FAV
 
 | | E491Q mutant of choline TMA-lyase | | 分子名称: | Choline trimethylamine-lyase, MALONATE ION, SODIUM ION | | 著者 | Funk, M.A, Drennan, C.L. | | 登録日 | 2015-12-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
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5FAY
 | | Y208F mutant of choline TMA-lyase | | 分子名称: | CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ... | | 著者 | Funk, M.A, Drennan, C.L. | | 登録日 | 2015-12-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
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6DCH
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5FAW
 | | T502A mutant of choline TMA-lyase | | 分子名称: | CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ... | | 著者 | Funk, M.A, Drennan, C.L. | | 登録日 | 2015-12-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
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5FAU
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6DS2
 | | Crystal structure of Ni(II)-bound human calprotectin | | 分子名称: | NICKEL (II) ION, Protein S100-A8, Protein S100-A9, ... | | 著者 | Nolan, E.M, Drennan, C.L, Nakashige, T.G. | | 登録日 | 2018-06-13 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site.
Biochemistry, 57, 2018
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6DC2
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6DJT
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2R0G
 | | Chromopyrrolic acid-soaked RebC with bound 7-carboxy-K252c | | 分子名称: | 7-carboxy-5-hydroxy-12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole, FLAVIN-ADENINE DINUCLEOTIDE, RebC | | 著者 | Ryan, K.S, Drennan, C.L. | | 登録日 | 2007-08-19 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QM8
 | | MeaB, A Bacterial Homolog of MMAA, in the Nucleotide Free Form | | 分子名称: | GTPase/ATPase, PHOSPHATE ION | | 著者 | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | | 登録日 | 2007-07-14 | | 公開日 | 2007-08-28 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria.
J.Biol.Chem., 282, 2007
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1X9Q
 | | 4m5.3 anti-fluorescein single chain antibody fragment (scFv) | | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 4m5.3 anti-fluorescein single chain antibody fragment, ACETATE ION | | 著者 | Midelfort, K.S, Hernandez, H.H, Lippow, S.M, Tidor, B, Drennan, C.L, Wittrup, K.D. | | 登録日 | 2004-08-24 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody
J.Mol.Biol., 343, 2004
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2R0P
 | | K252c-soaked RebC | | 分子名称: | 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Ryan, K.S, Drennan, C.L. | | 登録日 | 2007-08-20 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QM7
 | | MeaB, A Bacterial Homolog of MMAA, Bound to GDP | | 分子名称: | GTPase/ATPase, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | | 著者 | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | | 登録日 | 2007-07-14 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria.
J.Biol.Chem., 282, 2007
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6EFN
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2R0C
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1XRS
 | | Crystal structure of Lysine 5,6-Aminomutase in complex with PLP, cobalamin, and 5'-deoxyadenosine | | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... | | 著者 | Berkovitch, F, Behshad, E, Tang, K.H, Enns, E.A, Frey, P.A, Drennan, C.L. | | 登録日 | 2004-10-15 | | 公開日 | 2004-11-09 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1ZZB
 | | Crystal Structure of CoII HppE in Complex with Substrate | | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, COBALT (II) ION, Hydroxypropylphosphonic Acid Epoxidase | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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1ZZ8
 | | Crystal Structure of FeII HppE in Complex with Substrate Form 2 | | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, FE (II) ION, Hydroxypropylphosphonic Acid Epoxidase | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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1ZZC
 | | Crystal Structure of CoII HppE in Complex with Tris Buffer | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, hydroxypropylphosphonic acid epoxidase | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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1ZZ6
 | | Crystal Structure of Apo-HppE | | 分子名称: | Hydroxypropylphosphonic Acid Epoxidase | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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1ZZ9
 | | Crystal Structure of FeII HppE | | 分子名称: | FE (II) ION, Hydroxypropylphosphonic Acid Epoxidase, SULFATE ION | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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1ZZ7
 | | Crystal Structure of FeII HppE in Complex with Substrate form 1 | | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, FE (II) ION, Hydroxyprophylphosphonic Acid Epoxidase | | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | | 登録日 | 2005-06-13 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Nature, 437, 2005
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4DJD
 | | Crystal structure of folate-free corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr) | | 分子名称: | 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, COBALAMIN, ... | | 著者 | Kung, Y, Doukov, T.I, Blasiak, L.C, Drennan, C.L. | | 登録日 | 2012-02-01 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
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4DJF
 | | Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant | | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ... | | 著者 | Kung, Y, Drennan, C.L. | | 登録日 | 2012-02-01 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
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4DJE
 | | Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate | | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ... | | 著者 | Kung, Y, Drennan, C.L. | | 登録日 | 2012-02-01 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.504 Å) | | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
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