6DS2

Crystal structure of Ni(II)-bound human calprotectin

Summary for 6DS2

Entry DOI	10.2210/pdb6ds2/pdb
Descriptor	Protein S100-A8, Protein S100-A9, SODIUM ION, ... (5 entities in total)
Functional Keywords	s100, nickel, sodium, ef-hand, metal binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	96923.73
Authors	Nolan, E.M.,Drennan, C.L.,Nakashige, T.G. (deposition date: 2018-06-13, release date: 2018-07-04, Last modification date: 2023-10-11)
Primary citation	Nakashige, T.G.,Bowman, S.E.J.,Zygiel, E.M.,Drennan, C.L.,Nolan, E.M. Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site. Biochemistry, 57:4155-4164, 2018 Cited by PubMed: 29890074 DOI: 10.1021/acs.biochem.8b00415 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation