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1SLQ
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Crystal structure of the trimeric state of the rhesus rotavirus VP4 membrane interaction domain, VP5CT
分子名称: VP4
著者Dormitzer, P.R, Nason, E.B, Prasad, B.V.V, Harrison, S.C.
登録日2004-03-06
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural rearrangements in the membrane penetration protein of a non-enveloped virus.
Nature, 430, 2004
1KQR
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BU of 1kqr by Molmil
Crystal Structure of the Rhesus Rotavirus VP4 Sialic Acid Binding Domain in Complex with 2-O-methyl-alpha-D-N-acetyl neuraminic acid
分子名称: 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, GLYCEROL, SULFATE ION, ...
著者Dormitzer, P.R, Sun, Z.-Y.J, Wagner, G, Harrison, S.C.
登録日2002-01-07
公開日2002-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site
Embo J., 21, 2002
1KRI
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BU of 1kri by Molmil
NMR Solution Structures of the Rhesus Rotavirus VP4 Sialic Acid Binding Domain without Ligand
分子名称: VP4
著者Dormitzer, P.R, Sun, Z.-Y.J, Wagner, G, Harrison, S.C.
登録日2002-01-09
公開日2002-03-27
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site
Embo J., 21, 2002
4V7Q
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BU of 4v7q by Molmil
Atomic model of an infectious rotavirus particle
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Core scaffold protein, ...
著者Settembre, E.C, Chen, J.Z, Dormitzer, P.R, Grigorieff, N, Harrison, S.C.
登録日2010-05-13
公開日2014-07-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic model of an infectious rotavirus particle.
Embo J., 30, 2011
3FMG
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BU of 3fmg by Molmil
Structure of rotavirus outer capsid protein VP7 trimer in complex with a neutralizing Fab
分子名称: CALCIUM ION, Fab of neutralizing antibody 4F8, heavy chain, ...
著者Aoki, S.T, Settembre, E.C, Trask, S.D, Greenberg, H.B, Harrison, S.C, Dormitzer, P.R.
登録日2008-12-22
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.
Science, 324, 2009
2AEN
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BU of 2aen by Molmil
Crystal structure of the rotavirus strain DS-1 VP8* core
分子名称: ETHANOL, GLYCEROL, Outer capsid protein VP4, ...
著者Monnier, N, Higo-Moriguchi, K, Sun, Z.-Y.J, Prasad, B.V.V, Taniguchi, K, Dormitzer, P.R.
登録日2005-07-22
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain
J.Virol., 80, 2006
2B4I
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BU of 2b4i by Molmil
Crystal Structure of the Rhesus Rotavirus VP5 Antigen Domain Trimer
分子名称: Outer capsid protein VP4
著者Yoder, J.D, Dormitzer, P.R.
登録日2005-09-24
公開日2006-04-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alternative intermolecular contacts underlie the rotavirus VP5(*) two- to three-fold rearrangement
Embo J., 25, 2006
2B4H
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BU of 2b4h by Molmil
Crystal Structure of the Rhesus Rotavirus VP5 Antigen Domain Dimer
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Outer capsid protein VP4
著者Yoder, J.D, Dormitzer, P.R.
登録日2005-09-24
公開日2006-04-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Alternative intermolecular contacts underlie the rotavirus VP5(*) two- to three-fold rearrangement
Embo J., 25, 2006
7KDP
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BU of 7kdp by Molmil
HCMV prefusion gB in complex with fusion inhibitor WAY-174865
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ...
著者Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X.
登録日2020-10-09
公開日2021-03-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Sci Adv, 7, 2021
7KDD
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BU of 7kdd by Molmil
HCMV postfusion gB in complex with SM5-1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ...
著者Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X.
登録日2020-10-08
公開日2021-03-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Sci Adv, 7, 2021
3RKI
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BU of 3rki by Molmil
Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A.
登録日2011-04-18
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.
Proc.Natl.Acad.Sci.USA, 108, 2011
5UGY
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BU of 5ugy by Molmil
Influenza hemagglutinin in complex with a neutralizing antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH65 heavy chain, ...
著者Whittle, J.R.R, Jenni, S, Harrison, S.C.
登録日2017-01-10
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
7UJA
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BU of 7uja by Molmil
Cryo-EM structure of Human respiratory syncytial virus F variant (construct pXCS847A)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab heavy chain, AM14 Fab light chain, ...
著者Lees, J.A, Ammirati, M, Han, S.
登録日2022-03-30
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine.
Sci Transl Med, 15, 2023
7UJ3
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BU of 7uj3 by Molmil
Crystal structure of Human respiratory syncytial virus F variant (construct pXCS847A)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RSV variant (construct pXCS847A) F1, RSV variant (construct pXCS847A) F2, ...
著者Han, S, Ammirati, M.
登録日2022-03-30
公開日2023-04-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine.
Sci Transl Med, 15, 2023
5IBU
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6652 Fab (unbound)
分子名称: 6652 Heavy Chain, 6652 Light Chain
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBT
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BU of 5ibt by Molmil
UCA Fab (unbound) from 6515 Lineage
分子名称: GLYCEROL, UCA Heavy Chain, UCA Light Chain
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBL
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BU of 5ibl by Molmil
Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6639 Heavy Chain, 6639 Light Chain, ...
著者Raymond, D.D, Harrison, S.C.
登録日2016-02-22
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
3GZT
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BU of 3gzt by Molmil
VP7 recoated rotavirus DLP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Outer capsid glycoprotein VP7
著者Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N.
登録日2009-04-07
公開日2009-07-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM
Proc.Natl.Acad.Sci.USA, 106, 2009
3GZU
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BU of 3gzu by Molmil
VP7 recoated rotavirus DLP
分子名称: Inner capsid protein VP2, Intermediate capsid protein VP6, ZINC ION
著者Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N.
登録日2009-04-07
公開日2009-07-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 106, 2009
7L7K
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BU of 7l7k by Molmil
Cryo-EM structure of protein encoded by vaccine candidate BNT162b2
分子名称: Spike glycoprotein
著者Lees, J.A, Han, S.
登録日2020-12-28
公開日2021-02-24
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献BNT162b vaccines protect rhesus macaques from SARS-CoV-2.
Nature, 592, 2021
7L7F
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BU of 7l7f by Molmil
Cryo-EM structure of human ACE2 receptor bound to protein encoded by vaccine candidate BNT162b1
分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein, Envelope glycoprotein fusion
著者Lees, J.A, Han, S.
登録日2020-12-28
公開日2021-02-24
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献BNT162b vaccines protect rhesus macaques from SARS-CoV-2.
Nature, 592, 2021
4HKB
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CH67 Fab (unbound) from the CH65-67 Lineage
分子名称: CH67 heavy chain, CH67 light chain
著者Schmidt, A.G, Harrison, S.C.
登録日2012-10-15
公開日2012-11-21
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK3
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BU of 4hk3 by Molmil
I2 Fab (unbound) from CH65-CH67 Lineage
分子名称: I2 heavy chain, I2 light chain
著者Schmidt, A.G, Harrison, S.C.
登録日2012-10-14
公開日2012-11-21
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKX
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Influenza hemagglutinin in complex with CH67 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ...
著者Schmidt, A.G, Harrison, S.C.
登録日2012-10-15
公開日2012-11-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK0
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UCA Fab (unbound) from CH65-CH67 Lineage
分子名称: UCA heavy chain, UCA light chain
著者Schmidt, A.G, Harrison, S.C.
登録日2012-10-14
公開日2012-11-21
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013

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