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6ZWK
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BU of 6zwk by Molmil
Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody)
Descriptor: CHLORIDE ION, Histone H2AX, SODIUM ION, ...
Authors:McEwen, A.G, Moeglin, E, Desplancq, D, Weiss, E, Poterszman, A.
Deposit date:2020-07-28
Release date:2021-07-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress.
Cancers (Basel), 13, 2021
6FCM
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BU of 6fcm by Molmil
Crystal structure of human PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
6FCN
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BU of 6fcn by Molmil
Crystal structure of human PCNA soaked with p47phox(106-127) peptide
Descriptor: Proliferating cell nuclear antigen
Authors:Housset, D, Frachet, P.
Deposit date:2017-12-20
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
8OMV
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BU of 8omv by Molmil
Crystal structure of the constitutively active S117E/S181E mutant of human IKK2
Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta
Authors:McEwen, A.G, Li, C, Moro, S, Poussin-Courmontagne, P, Zanier, K.
Deposit date:2023-03-31
Release date:2024-04-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (4.16 Å)
Cite:Molecular mechanism of IKK catalytic dimer docking to NF-kappa B substrates.
Nat Commun, 15, 2024
2FK4
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BU of 2fk4 by Molmil
Solution structure of the C-terminal zinc binding domain of the HPV16 E6 oncoprotein
Descriptor: Protein E6, ZINC ION
Authors:Nomine, Y, Charbonnier, S.
Deposit date:2006-01-04
Release date:2006-01-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis
Mol.Cell, 21, 2006
4NIK
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BU of 4nik by Molmil
Structure of human Gankyrin in complex to the single chain antibody F5
Descriptor: 26S proteasome non-ATPase regulatory subunit 10, Single-chain Fv fragment antibody
Authors:Sato, Y, Weiss, E, Rochel, N.
Deposit date:2013-11-06
Release date:2014-09-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes
J.Mol.Biol., 426, 2014

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