4TGL
 
 | | CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE | | 分子名称: | DIETHYL PHOSPHONATE, TRIACYL-GLYCEROL ACYLHYDROLASE | | 著者 | Derewenda, U, Brzozowski, A.M, Lawson, D, Derewenda, Z.S. | | 登録日 | 1991-07-29 | | 公開日 | 1993-07-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase.
Biochemistry, 31, 1992
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6INS
 | | X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE | | 分子名称: | INSULIN, ZINC ION | | 著者 | Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. | | 登録日 | 1992-11-25 | | 公開日 | 1994-01-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
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4GUE
 | | Structure of N-terminal kinase domain of RSK2 with flavonoid glycoside quercitrin | | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, Ribosomal protein S6 kinase alpha-3, ... | | 著者 | Derewenda, U, Utepbergenov, D, Szukalska, G, Derewenda, Z.S. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013
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2V71
 | | Coiled-coil region of NudEL | | 分子名称: | NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 | | 著者 | Derewenda, U, Cooper, D.R, Kim, M.H, Derewenda, Z.S. | | 登録日 | 2007-07-25 | | 公開日 | 2007-11-27 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
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3FHK
 | | Crystal structure of APC1446, B.subtilis YphP disulfide isomerase | | 分子名称: | SULFATE ION, UPF0403 protein yphP | | 著者 | Derewenda, U, Boczek, T, Cooper, D.R, Yu, M, Hung, L, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | 登録日 | 2008-12-09 | | 公開日 | 2009-09-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif .
Biochemistry, 48, 2009
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1TIB
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1TIC
 | | CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR | | 分子名称: | LIPASE | | 著者 | Derewenda, U, Swenson, L, Green, R, Joerger, R, Haas, M.J, Derewenda, Z.S. | | 登録日 | 1993-12-06 | | 公開日 | 1995-01-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar.
J.Lipid Res., 35, 1994
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1R6F
 | | The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague | | 分子名称: | Virulence-associated V antigen | | 著者 | Derewenda, U, Mateja, A, Devedjiev, Y, Routzahn, K.M, Evdokimov, A.G, Derewenda, Z.S, Waugh, D.S. | | 登録日 | 2003-10-15 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague
Structure, 12, 2004
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1TIA
 | | AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES | | 分子名称: | LIPASE | | 著者 | Derewenda, U, Swenson, L, Yamaguchi, S, Wei, Y, Derewenda, Z.S. | | 登録日 | 1993-12-06 | | 公開日 | 1995-01-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An unusual buried polar cluster in a family of fungal lipases.
Nat.Struct.Biol., 1, 1994
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1XAS
 | | CRYSTAL STRUCTURE, AT 2.6 ANGSTROMS RESOLUTION, OF THE STREPTOMYCES LIVIDANS XYLANASE A, A MEMBER OF THE F FAMILY OF BETA-1,4-D-GLYCANSES | | 分子名称: | 1,4-BETA-D-XYLAN XYLANOHYDROLASE | | 著者 | Derewenda, U, Derewenda, Z.S. | | 登録日 | 1994-05-31 | | 公開日 | 1995-05-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases.
J.Biol.Chem., 269, 1994
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1XCG
 | | Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF | | 分子名称: | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA | | 著者 | Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S. | | 登録日 | 2004-09-01 | | 公開日 | 2004-12-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
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1KTJ
 | | X-ray Structure Of Der P 2, The Major House Dust Mite Allergen | | 分子名称: | ALLERGEN DER P 2 | | 著者 | Derewenda, U, Li, J, Derewenda, Z, Dauter, Z, Mueller, G.A, Rule, G.S, Benjamin, D.C. | | 登録日 | 2002-01-16 | | 公開日 | 2002-05-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
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5IRC
 | | p190A GAP domain complex with RhoA | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Derewenda, U, Derewenda, Z. | | 登録日 | 2016-03-12 | | 公開日 | 2016-08-17 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
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4QAZ
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4QB0
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3QOR
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1BWQ
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 著者 | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | 登録日 | 1998-09-27 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
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1BWP
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 著者 | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | 登録日 | 1998-09-27 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
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1BWR
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 分子名称: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 著者 | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | 登録日 | 1998-09-27 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
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1CC0
 | | CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... | | 著者 | Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | | 登録日 | 1999-03-03 | | 公開日 | 2000-01-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
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6B6Z
 | | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | | 分子名称: | Apo Fab Heavy Chain, Apo Fab Light Chain, ZINC ION | | 著者 | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | | 登録日 | 2017-10-03 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | | 主引用文献 | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
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5TGL
 | | A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX | | 分子名称: | LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER | | 著者 | Brzozowski, A.M, Derewenda, U, Derewenda, Z.S, Dodson, G.G, Lawson, D, Turkenburg, J.P, Bjorkling, F, Huge-Jensen, B, Patkar, S.R, Thim, L. | | 登録日 | 1991-10-30 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351, 1991
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5E2X
 | | The crystal structure of the C-terminal domain of Ebola (Tai Forest) nucleoprotein | | 分子名称: | NONAETHYLENE GLYCOL, NP | | 著者 | Baker, L.E, Handing, K.B, Derewenda, U, Utepbergenov, D, Derewenda, Z.S. | | 登録日 | 2015-10-01 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
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5DSD
 | | The crystal structure of the C-terminal domain of Ebola (Bundibugyo) nucleoprotein | | 分子名称: | CHLORIDE ION, GLYCEROL, Nucleoprotein | | 著者 | Baker, L, Handing, K.B, Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2015-09-17 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Acta Crystallogr D Struct Biol, 72, 2016
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5VIM
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