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1SL7
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BU of 1sl7 by Molmil
Crystal structure of calcium-loaded apo-obelin from Obelia longissima
分子名称: CALCIUM ION, Obelin
著者Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.J, Lee, J, Rose, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-03-05
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Protein Sci., 14, 2005
1S36
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BU of 1s36 by Molmil
Crystal structure of a Ca2+-discharged photoprotein: Implications for the mechanisms of the calcium trigger and the bioluminescence
分子名称: CHLORIDE ION, GLYCEROL, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, ...
著者Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.-J, Lee, J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-01-12
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of a Ca2+-discharged photoprotein: implications for mechanisms of the calcium trigger and bioluminescence
J.Biol.Chem., 279, 2004
1SL9
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BU of 1sl9 by Molmil
Obelin from Obelia longissima
分子名称: C2-HYDROPEROXY-COELENTERAZINE, Obelin
著者Deng, L, Markova, S, Vysotski, E, Liu, Z.-J, Lee, J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-03-05
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Obelin from Obelia longissima
To be Published
1SL8
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BU of 1sl8 by Molmil
Calcium-loaded apo-aequorin from Aequorea victoria
分子名称: Aequorin 1, CALCIUM ION
著者Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.J, Lee, J, Rose, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-03-05
公開日2004-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin.
Protein Sci., 14, 2005
1JF0
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BU of 1jf0 by Molmil
The Crystal Structure of Obelin from Obelia geniculata at 1.82 A Resolution
分子名称: C2-HYDROPEROXY-COELENTERAZINE, Obelin
著者Deng, L, Vysotski, E, Liu, Z.-J, Markova, S, Lee, J, Rose, J, Wang, B.-C.
登録日2001-06-19
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Crystal Structure of Obelin from Obelia geniculata at 1.82 Angstrom Resolution
To be Published
2IAL
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BU of 2ial by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAM
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BU of 2iam by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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BU of 2ian by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
4Q0X
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BU of 4q0x by Molmil
Crystal structure of non-neutralizing antibody in complex with Epitope II of HCV E2
分子名称: Envelope glycoprotein E2, mAb 12 heavy chain, mAb 12 light chain
著者Deng, L, Zhang, P.
登録日2014-04-02
公開日2014-07-09
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
3M19
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BU of 3m19 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R5.1
分子名称: Variable lymphocyte receptor A diversity region
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2010-03-04
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M18
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BU of 3m18 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme
分子名称: Lysozyme C, PHOSPHATE ION, Variable lymphocyte receptor A diversity region
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2010-03-04
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
1PRY
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BU of 1pry by Molmil
Structure Determination of Fibrillarin Homologue From Hyperthermophilic Archaeon Pyrococcus furiosus (Pfu-65527)
分子名称: Fibrillarin-like pre-rRNA processing protein
著者Deng, L, Starostina, N.G, Liu, Z.-J, Rose, J.P, Terns, R.M, Terns, M.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-06-20
公開日2004-03-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure determination of fibrillarin from the hyperthermophilic archaeon Pyrococcus furiosus
Biochem.Biophys.Res.Commun., 315, 2004
1YWO
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BU of 1ywo by Molmil
Phospholipase Cgamma1 SH3 in complex with a SLP-76 motif
分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, Lymphocyte cytosolic protein 2
著者Deng, L, Velikovsky, C.A, Swaminathan, C.P, Cho, S, Mariuzza, R.A.
登録日2005-02-18
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
1YWP
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BU of 1ywp by Molmil
Phospholipase Cgamma1 SH3
分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
著者Deng, L, Velikovsky, C.A, Swaminathan, C.P, Cho, S, Mariuzza, R.A.
登録日2005-02-18
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
3C8J
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BU of 3c8j by Molmil
The crystal structure of natural killer cell receptor Ly49C
分子名称: Natural killer cell receptor Ly49C
著者Deng, L, Mariuzza, R.A.
登録日2008-02-12
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
3C8K
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BU of 3c8k by Molmil
The crystal structure of Ly49C bound to H-2Kb
分子名称: H-2 class I histocompatibility antigen, K-B alpha chain, Natural killer cell receptor Ly-49C, ...
著者Deng, L, Mariuzza, R.A.
登録日2008-02-12
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
4HZL
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BU of 4hzl by Molmil
Neutralizing antibody mAb#8 in complex with the Epitope II of HCV E2 envelope protein
分子名称: E2 envelop protein, Fab heavy chain, Fab light chain
著者Deng, L, Zhang, P.
登録日2012-11-15
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4E41
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BU of 4e41 by Molmil
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A.
登録日2012-03-11
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
4E42
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BU of 4e42 by Molmil
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
分子名称: CHLORIDE ION, NITRATE ION, SODIUM ION, ...
著者Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A.
登録日2012-03-11
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
7LKI
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BU of 7lki by Molmil
The crystal structure of Epitope III of HCV envelop protein E2 in complex with antibody 1H8
分子名称: Epitope III peptide GLY-ALA-PRO-THR-TYR-SER-TRP-GLY, antibody 1H8 heavy chain, antibody 1H8 light chain
著者Deng, L, Zhang, P.
登録日2021-02-02
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A conserved epitope III on hepatitis C virus E2 protein has alternate conformations facilitating cell binding or virus neutralization.
Proc.Natl.Acad.Sci.USA, 118, 2021
3RAS
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BU of 3ras by Molmil
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-(N-HYDROXYACETAMIDO)-1-(3,4-DICHLOROPHENYL)PROPYLPHOSPHONIC ACID, MANGANESE (II) ION, ...
著者Diao, J, Deng, L, Prasad, B.V.V, Song, Y.
登録日2011-03-28
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.
J.Med.Chem., 54, 2011
2PTT
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BU of 2ptt by Molmil
Structure of NK cell receptor 2B4 (CD244) bound to its ligand CD48
分子名称: CD48 antigen, Natural killer cell receptor 2B4, SULFATE ION
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2007-05-08
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTU
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BU of 2ptu by Molmil
Structure of NK cell receptor 2B4 (CD244)
分子名称: Natural killer cell receptor 2B4
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2007-05-08
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTV
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BU of 2ptv by Molmil
Structure of NK cell receptor ligand CD48
分子名称: CD48 antigen
著者Deng, L, Velikovsky, C.A, Mariuzza, R.A.
登録日2007-05-08
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
3ANM
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BU of 3anm by Molmil
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with 5-phenylpyridin-2-ylmethylphosphonic acid
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(5-phenylpyridin-2-yl)methyl]phosphonic acid
著者Endo, K, Kato, M, Deng, L, Song, Y, Yajima, S.
登録日2010-09-03
公開日2011-02-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes
ACS Med Chem Lett, 2, 2011

 

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