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Cryo-EM structure of complement C5 in complex with nanobodies UNbC5-1 and UNbC5-2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ...
Authors:	De la O Becerra, K.I, Gros, P.
Deposit date:	2023-02-20
Release date:	2023-09-27
Last modified:	2024-11-06
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies. J.Biol.Chem., 299, 2023

Cryo-EM structure of complement C4b in complex with nanobody B5
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4 alpha chain, ...
Authors:	Oosterheert, W, De la O Becerra, K.I, Gros, P.
Deposit date:	2020-11-27
Release date:	2022-03-02
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (3.43 Å)
Cite:	Multifaceted Activities of Seven Nanobodies against Complement C4b. J Immunol., 208, 2022

Cryo-EM structure of complement C4b in complex with nanobody E3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-C4b nanobody E3, Complement C4 alpha chain, ...
Authors:	Oosterheert, W, De la O Becerra, K.I, van den Bos, R.M, Gros, P.
Deposit date:	2020-11-27
Release date:	2022-03-02
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (3.39 Å)
Cite:	Multifaceted Activities of Seven Nanobodies against Complement C4b. J Immunol., 208, 2022

Cryo-EM structure of complement C4b in complex with nanobody B12
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-C4b nanobody B12, ...
Authors:	Oosterheert, W, De la O Becerra, K.I, Gros, P.
Deposit date:	2020-11-27
Release date:	2022-03-02
Last modified:	2024-11-20
Method:	ELECTRON MICROSCOPY (3.76 Å)
Cite:	Multifaceted Activities of Seven Nanobodies against Complement C4b. J Immunol., 208, 2022