3VPS
 
 | | Structure of a novel NAD dependent-NDP-hexosamine 5,6-dehydratase, TunA, involved in tunicamycin biosynthesis | | Descriptor: | NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | | Authors: | Wyszynski, F.J, Lee, S.S, Yabe, T, Wang, H, Gomez-Escribano, J.P, Bibb, M.J, Lee, S.J, Davies, G.J, Davis, B.G. | | Deposit date: | 2012-03-12 | | Release date: | 2012-04-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Biosynthesis of nucleoside antibiotic tunicamycin proceeds via unique exo-glycal intermediates
To be published
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8RLB
 | | RECQL5:sfGFP hetero dimer assembled by Di-Gluebody - sfGFP local refinement | | Descriptor: | Gluebody G5-006, Gluebody GbEnhancer, Green fluorescent protein | | Authors: | Yi, G, Ye, M, Mamalis, D, Fairhead, M, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RL8
 | | SPNS2 in complex with homo Di-Gluebody GbD12 - SPNS2 local refinement | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Sphingosine-1-phosphate transporter SPNS2 | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RLD
 | | SPNS2:sfGFP hetero dimer assembled by Di-Gluebody - SPNS2 local refinement | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Sphingosine-1-phosphate transporter SPNS2 | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RLC
 | | SPNS2:sfGFP hetero dimer assembled by Di-Gluebody | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gluebody GbC4, Gluebody GbEnhancer, ... | | Authors: | Yi, G, Ye, M, Mamalis, D, Li, H, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RL7
 | | SPNS2 in complex with homo Di-Gluebody GbD12 | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gluebody GbD12, Sphingosine-1-phosphate transporter SPNS2 | | Authors: | Yi, G, Ye, M, Mamalis, D, Li, H, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.76 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RL9
 | | RECQL5:sfGFP hetero dimer assembled by Di-Gluebody | | Descriptor: | ATP-dependent DNA helicase Q5, Gluebody G5-006, Gluebody GbEnhancer, ... | | Authors: | Yi, G, Ye, M, Mamalis, D, Fairhead, M, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RL6
 | | DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 - RECQL5 local refinement | | Descriptor: | ATP-dependent DNA helicase Q5, ZINC ION | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RL5
 | | DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 | | Descriptor: | ATP-dependent DNA helicase Q5, Gluebody G5-006, ZINC ION | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RLE
 | | SPNS2:sfGFP hetero dimer assembled by Di-Gluebody - sfGFP local refinement | | Descriptor: | Gluebody GbC4, Gluebody GbEnhancer, Green fluorescent protein | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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8RLA
 | | RECQL5:sfGFP hetero dimer assembled by Di-Gluebody - RECQL5 local refinement | | Descriptor: | ATP-dependent DNA helicase Q5, Gluebody G5-006, ZINC ION | | Authors: | Yi, G, Ye, M, Mamalis, D, Sauer, D.B, von Delft, F, Davis, B.G, Gilbert, R.J.C. | | Deposit date: | 2024-01-02 | | Release date: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures
To Be Published
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5ARB
 | | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | | Descriptor: | 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | | Deposit date: | 2015-09-24 | | Release date: | 2016-09-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
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5AQE
 | | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | | Descriptor: | (4-VINYLPHENYL)METHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | | Deposit date: | 2015-09-22 | | Release date: | 2015-10-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Bisubstrate Localisation by a Tailored Serine Protease Allows Creation of a Heck-Ase
To be Published
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5ARC
 | | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | | Descriptor: | 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, GLYCEROL, ... | | Authors: | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | | Deposit date: | 2015-09-24 | | Release date: | 2016-09-14 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
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5ARD
 | | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | | Descriptor: | 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, GLYCEROL, ... | | Authors: | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | | Deposit date: | 2015-09-24 | | Release date: | 2016-09-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
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6EQL
 | | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP | | Descriptor: | 1,2-ETHANEDIOL, Glycogenin-1, MANGANESE (II) ION, ... | | Authors: | Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W. | | Deposit date: | 2017-10-13 | | Release date: | 2017-12-20 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
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6EQJ
 | | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form | | Descriptor: | 1,2-ETHANEDIOL, Glycogenin-1 | | Authors: | Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W. | | Deposit date: | 2017-10-13 | | Release date: | 2017-12-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
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3OAZ
 | | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | | Descriptor: | CHLORIDE ION, Fab 2G12, heavy chain, ... | | Authors: | Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. | | Deposit date: | 2010-08-06 | | Release date: | 2011-01-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3OAY
 | | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | | Descriptor: | Fab 2G12, heavy chain, light chain, ... | | Authors: | Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. | | Deposit date: | 2010-08-05 | | Release date: | 2011-01-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3OB0
 | | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | | Descriptor: | 7-deoxy-L-glycero-alpha-D-manno-heptopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, Fab 2G12, heavy chain, ... | | Authors: | Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. | | Deposit date: | 2010-08-06 | | Release date: | 2011-01-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2BO4
 | | Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase | | Descriptor: | CITRATE ANION, MANNOSYLGLYCERATE SYNTHASE | | Authors: | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2005-04-07 | | Release date: | 2005-06-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
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2BO6
 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | (2R)-2,3-DIHYDROXYPROPANOIC ACID, MANGANESE (II) ION, MANNOSYLGLYCERATE SYNTHASE | | Authors: | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
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2BO8
 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | CHLORIDE ION, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ... | | Authors: | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
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2BO7
 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | Descriptor: | COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, MANNOSYLGLYCERATE SYNTHASE | | Authors: | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | | Deposit date: | 2005-04-08 | | Release date: | 2005-06-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
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2C1Z
 | | Structure and activity of a flavonoid 3-O glucosyltransferase reveals the basis for plant natural product modification | | Descriptor: | 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, UDP-GLUCOSE FLAVONOID 3-O GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | | Authors: | Offen, W, Martinez-Fleites, C, Kiat-Lim, E, Yang, M, Davis, B.G, Tarling, C.A, Ford, C.M, Bowles, D.J, Davies, G.J. | | Deposit date: | 2005-09-22 | | Release date: | 2006-01-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification.
Embo J., 25, 2006
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