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Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor
Descriptor:	5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ...
Authors:	Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M.
Deposit date:	2014-11-04
Release date:	2015-04-08
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.63 Å)
Cite:	LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J.Biol.Chem., 290, 2015

Parallel 17-mer DNA G-quadruplex
Descriptor:	DNA (5'-D(GPGPGPTPGPGPGPAPAPGPGPGPTPGPGPGP*A)-3')
Authors:	Srb, P, Curtis, C, Veverka, V.
Deposit date:	2020-05-04
Release date:	2021-01-20
Last modified:	2024-06-19
Method:	SOLUTION NMR
Cite:	Overlapping but distinct: a new model for G-quadruplex biochemical specificity. Nucleic Acids Res., 49, 2021

Influenza Neuraminidase in complex with a stereomutated analogue of Oseltamivir carboxylate
Descriptor:	(3R,4S,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:	Kerry, P.S.
Deposit date:	2013-08-06
Release date:	2014-02-12
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate. Org.Biomol.Chem., 12, 2014