5OIK
| Structure of an RNA polymerase II-DSIF transcription elongation complex | Descriptor: | DNA (43-MER), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Bernecky, C, Plitzko, J.M, Cramer, P. | Deposit date: | 2017-07-18 | Release date: | 2017-09-13 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
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5OLA
| Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM | Descriptor: | DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ... | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | Deposit date: | 2017-07-27 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.904 Å) | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
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6R80
| Structure of AFF4 C-terminal homology domain | Descriptor: | AF4/FMR2 family member 4 | Authors: | Chen, Y, Cramer, P. | Deposit date: | 2019-03-30 | Release date: | 2019-06-12 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. J.Biol.Chem., 294, 2019
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5OL8
| Structure of human mitochondrial transcription elongation factor (TEFM) C-terminal domain | Descriptor: | GLYCEROL, Transcription elongation factor, mitochondrial | Authors: | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | Deposit date: | 2017-07-27 | Release date: | 2017-10-18 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of Transcription Anti-termination in Human Mitochondria. Cell, 171, 2017
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5OHO
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5OQM
| STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. | Deposit date: | 2017-08-13 | Release date: | 2018-05-09 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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6RIE
| Structure of Vaccinia Virus DNA-dependent RNA polymerase co-transcriptional capping complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
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5OT2
| RNA polymerase II elongation complex in the presence of 3d-Napht-A | Descriptor: | 2-ethyl-7-methoxy-naphthalene, DNA non-template strand, DNA template strand, ... | Authors: | Malvezzi, S, Farnung, L, Aloisi, C, Angelov, T, Cramer, P, Sturla, S.J. | Deposit date: | 2017-08-19 | Release date: | 2017-11-01 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Mechanism of RNA polymerase II stalling by DNA alkylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6RID
| Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
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5OQJ
| STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | Descriptor: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | Deposit date: | 2017-08-11 | Release date: | 2018-04-25 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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6RYU
| Nucleosome-CHD4 complex structure (two CHD4 copies) | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | Authors: | Farnung, L, Ochmann, M, Cramer, P. | Deposit date: | 2019-06-12 | Release date: | 2020-07-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
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6RYR
| Nucleosome-CHD4 complex structure (single CHD4 copy) | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | Authors: | Farnung, L, Ochmann, M, Cramer, P. | Deposit date: | 2019-06-11 | Release date: | 2020-07-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
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6RO4
| Structure of the core TFIIH-XPA-DNA complex | Descriptor: | DNA repair protein complementing XP-A cells, DNA1, DNA2, ... | Authors: | Kokic, G, Chernev, A, Tegunov, D, Dienemann, C, Urlaub, H, Cramer, P. | Deposit date: | 2019-05-10 | Release date: | 2019-07-03 | Last modified: | 2019-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of TFIIH activation for nucleotide excision repair. Nat Commun, 10, 2019
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6RFL
| Structure of the complete Vaccinia DNA-dependent RNA polymerase complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Grimm, C, Hillen, S.H, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A.A, Cramer, P, Fischer, U. | Deposit date: | 2019-04-15 | Release date: | 2019-12-11 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes. Cell, 179, 2019
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6S01
| Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | Deposit date: | 2019-06-13 | Release date: | 2019-12-18 | Last modified: | 2020-01-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
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6RIC
| Structure of the core Vaccinia Virus DNA-dependent RNA polymerase complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Grimm, C, Hillen, H.S, Bedenk, K, Bartuli, J, Neyer, S, Zhang, Q, Huettenhofer, A, Erlacher, M, Dienemann, C, Schlosser, A, Urlaub, H, Boettcher, B, Szalay, A, Cramer, P, Fischer, U. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
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6T7A
| Structure of human Sox11 transcription factor in complex with a nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | Deposit date: | 2019-10-21 | Release date: | 2020-04-29 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
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6TED
| Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | Authors: | Vos, S.M, Farnung, L, Cramer, P. | Deposit date: | 2019-11-11 | Release date: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
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6T7B
| Structure of human Sox2 transcription factor in complex with a nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | Deposit date: | 2019-10-21 | Release date: | 2020-04-29 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
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6T9K
| SAGA Core module | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T79
| Structure of a human nucleosome at 3.2 A resolution | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | Deposit date: | 2019-10-21 | Release date: | 2020-04-29 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
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6T7D
| Structure of human Sox11 transcription factor in complex with a nucleosome | Descriptor: | DNA (151-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | Deposit date: | 2019-10-21 | Release date: | 2020-04-29 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
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6T9J
| SAGA Tra1 module | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9I
| cryo-EM structure of transcription coactivator SAGA | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T7C
| Structure of two copies of human Sox11 transcription factor in complex with a nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | Deposit date: | 2019-10-21 | Release date: | 2020-04-29 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
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