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5E9J
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BU of 5e9j by Molmil
Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, mRNA cap guanine-N7 methyltransferase,mRNA cap guanine-N7 methyltransferase
Authors:Petit, P, Cowling, V.H.
Deposit date:2015-10-15
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Nucleic Acids Res., 44, 2016
5E9W
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BU of 5e9w by Molmil
Crystal structure of mRNA cap guanine-N7 methyltransferase obtained by limited proteolysis
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, mRNA cap guanine-N7 methyltransferase
Authors:Petit, P, Cowling, V.H.
Deposit date:2015-10-15
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.283 Å)
Cite:Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Nucleic Acids Res., 44, 2016
5E8J
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BU of 5e8j by Molmil
Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with RAM
Descriptor: GLYCEROL, RNMT-activating mini protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Petit, P, Cowling, V.
Deposit date:2015-10-14
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Nucleic Acids Res., 44, 2016
8Q69
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BU of 8q69 by Molmil
Crystal structure of HsRNMT complexed with inhibitor DDD1060606
Descriptor: 1-[(3~{S})-3-(2~{H}-pyrazolo[3,4-b]pyridin-3-yl)piperidin-1-yl]-2-thiophen-3-yl-ethanone, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Petit, A.P, Fyfe, P.K.
Deposit date:2023-08-11
Release date:2024-08-21
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach.
Biochem.J., 482, 2025
8Q8G
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BU of 8q8g by Molmil
Crystal structure of HsRNMT complexed with inhibitor DDD1870799
Descriptor: 2-(4-fluorophenyl)-1-[(3~{S})-3-(6-oxidanyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)piperidin-1-yl]ethanone, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Petit, A.P, Fyfe, P.K.
Deposit date:2023-08-18
Release date:2024-08-28
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach.
Biochem.J., 482, 2025
8Q9W
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BU of 8q9w by Molmil
Crystal structure of HsRNMT complexed with sinefungin and GMP-PnP
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SINEFUNGIN, SULFATE ION, ...
Authors:Petit, A.P, Fyfe, P.K.
Deposit date:2023-08-21
Release date:2024-09-11
Last modified:2025-03-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach.
Biochem.J., 482, 2025

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PDB entries from 2025-07-09

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